Award Data

Employment is essential for helping individuals with intellectual disabilities achieve independence, financial security, and self-sufficiency to be active members in the community as well as foster a higher quality of life more generally. However, only 25% of individuals with intellectual disabilities are employed two years after high school. Utilizing 3C’s proprietary dynamic e-learning platfor ...

ABSTRACT: Autonomous vehicles lack a standardized mechanism for seamless cross-platform sharing of testing frameworks and evaluations of basic tasks. The ability to execute common tests on various hardware platforms is essential in order to be able to e

The project team is developing a prototype of Lightning Squad: Powered-Up Reading with Teams, a multimedia tutoring tool that will be used by paraprofessionals working with up to six 1st to 3rd grade students who need extra support in reading. The tutoring program will build on the Success for All whole school reading program through the incorporation of video segments and gaming content. The prod ...

DESCRIPTION provided by applicant Sanfilippo disease mucopolysaccharidosis type III MPS III is a devastating neurodegenerative lysosomal storage disorder of childhood for which there is no cure or effective treatment available The fundamental cause of MPS III is an inherited mutation in one of the enzymes required to catabolize heparan sulfate HS a glycosaminoglycan which plays importa ...

DESCRIPTION provided by applicant The ultimate objective of this program is to develop a novel therapeutic approach that will save lives of patients with stroke Acute stroke is the third leading cause of death in the United States and the primary medical cause of acquired adult disability Each year Americans experience new or recurrent stroke It accounts for out of every death ...

DESCRIPTION provided by applicant Approximately one third of all U S adults and children are obese and at risk for a wide range of related chronic health conditions such as cardiovascular disease hypertension diabetes stroke osteoarthritis sleep apnea and certain types of cancer The Center for Disease Control and Prevention CDC and other expert resources recognize that although indivi ...

DESCRIPTION provided by applicant Hematopoietic stem cell transplantation is a form of stem cell therapy used to treat cancers such as lymphoma and leukemia and other blood related diseases However there currently are several drawbacks in the use of bone marrow hematopoietic cell transplantation Most importantly the donor pool is limited by the need for at least partial HLA matching and t ...

DESCRIPTION provided by applicant Current seasonal Influenza vaccines are proving to be ineffective especially in at risk populations For example this yearandapos s inactivated flu vaccine had only a efficacy rate against H N infections in the elderly and the current live attenuated Influenza vaccine LAIV is aged restricted for those above years of age Therefore there is glaring un ...

DESCRIPTION provided by applicant Genetic or pharmacologic inhibition of ceramide mediated cell death within the vascular endothelium of the gastrointestinal tract GI protects mice from death from the Radiation GI Syndrome RGS Prophylactic administration of anti ceramide antibody attenuates endothelial apoptosis resulting in significant protection of intestinal stem cells and animal survi ...

DESCRIPTION provided by applicant Babesia microti the primary etiologic agent of human babesiosis is a tick borne eukaryotic apicomplexan pathogen that is an increasing threat to the US public health Although B microti is primarily a tick borne pathogen it can be transmitted by transfusion of infected blood Despite the well recognized threat there is no FDA licensed test to screen donor ...