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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Building Teacher Mastery via an Internet Training System

    SBC: TANGLEWOOD RESEARCH INC            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of this Phase II STTR is to complete the development of a web-based training system, the All Stars Online Community. This system is designed to improve teachers' delivery of All Stars, an adolescent substance use prevention program. The goal of training is to help teachers advance in their teaching skills and understanding of underlying preventi ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Data acquisition system for noninvasive cancer detection

    SBC: Biophotonics Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of the proposal is to develop an automated data acquisition system for non-invasive quantitative cancer detection, screening, and monitoring, based on highly sensitive low volume real time PCR technique and capillary electrophoresis, apply this system for quantitative analysis of the telomerase activity and gene expression in single cancer c ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Therapy for Asthma Targeting beta-Adrenoceptors

    SBC: INVERSEON, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Asthma is a chronic inflammatory disease that effects approximately 17 million Americans. Despite the availability of inhaled beta-adrenoceptor (betaAR) agonists and corticosteroids, 1.8 million emergency room visits a year occur due to severe asthma attacks demonstrating a significant unmet medical need. The Company intends to develop and commercialize INV102, ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Combo beta-blockers & beta2-agonists for asthma therapy

    SBC: INVERSEON, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Approximately 5% of Americans have asthma, an inflammatory airway disease whose hallmark is airway hyper-reactivity (AHR). During AHR, bronchial smooth muscles rapidly constrict resulting in airway obstruction. Most patients self-administer inhaled beta2-adrenoceptor (beta2AR) agonists such as salmeterol for relief of this life-threatening event. Unfortunately, ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Image-Guided Minimally Invasive Robotic Surgery

    SBC: INTUITIVE SURGICAL            Topic: N/A

    DESCRIPTION (provided by applicant): Image-guided surgery allows surgeons to specifically target diseased tissue while sparing healthy tissue, reducing morbidity and improving patient outcomes. Minimally invasive surgical techniques deliver specific intervention without the morbidity associated with large open incisions. Image-guidance technology has the potential to provide significant benefit ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  6. In vivo Clinical Coherence Confocal Microscope

    SBC: LUCID, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Phase I Reflectance confocal microscopy images the cellular and structural morphology of tissue in-vivo or ex-vivo without the need for histological processing. Existing reflectance confocal microscopes use single wavelength laser to generate gray scale intensity images. The goals of this proposal are to build and characterize a coherence reflectance c ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. Thinner Silicon Detectors and Novel Interconnections for Robust High Energy Physics Detectors

    SBC: DIGITAL OPTICS CORP.            Topic: 8

    76214-Next generation experiments in High Energy Physics require the use of thinned detectors with high density interconnects; however, present manufacturing techniques for wafer thinning produce very low yields. Standard processing techniques have proven to be unacceptable for the production of high pixel count detector assemblies. Therefore, this project will develop technology for plasma-etch ...

    STTR Phase I 2004 Department of Energy
  8. Heterologous Production of Eleutherobin Precursors

    SBC: AMYRIS BIOTECHNOLOGIES            Topic: N/A

    DESCRIPTION (provided by applicant): Terpenoids are a diverse class of natural compounds with equally diverse and potent bioactivities. Because the practical use of terpenoids hinges on the ability to extract or synthesize these compounds, only the most abundant or easily synthesized compounds have been commercially developed. The long-term goal of this Small Business Technology Transfer Phase I p ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. Gene Enhanced Tissue Engineering for Bone Regeneration

    SBC: TISSUEGENESIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The development of novel and improved technologies for bone regeneration is desirable in many clinical applications, especially in dental and craniofacial reconstruction and fracture repair. Optimal bone regeneration requires the interaction of three components at the site of injury. These include: the presence of appropriate cell type(s) with bone regenerative ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. New Topical Therapies for Psoriasis

    SBC: BETHESDA PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Psoriasis is a common, inflammatory disease of the skin characterized by hyperproliferation of keratinocytes. A variety of antipsoriatic therapies are available, however, due to problems with side effects and variability in clinical response, intense clinical and commercial interest remains in the development of new treatments. In the current studies, we will ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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