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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Novel Protection Device for Shock Wave Lithotripter

    SBC: Genognomon, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The shock wave lithotripsy (SWL) was first introduced successfully in clinical treatment in the earlier 1980s by Dornier Medical System in Germany. Now it has become the modality for urolithiasis diseases. However, SWL also causes acute renal injury, such as hemorrhage, hematoma, edema and enlargement of kidney. Although most patients recover well following ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Device for overground gait/balance training post-stroke

    SBC: Kinea Design, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Chicago PT is developing rehabilitation robotics to help clinicians provide more intensive functional retraining of overground walking, post-stroke. Chicago PT's concept is to build devices that work with the clinician rather than replacing the clinician, in order to retain the clinician's skilled manual connection with the patient in all its important aspects: ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Catalytic DNA Biosensor for Toxic Metal Ions

    SBC: ANDALYZE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A general method of developing catalytic DNA biosensors for on-site, real-time, and cost-effective detection and quantification of multiple heavy metal ions, such as mercury, cadmium and lead, simultaneously will be explored. Exposure to these metal ions can bring severe health effects to human beings, such as damages to brain and kidneys, and cancers. They can ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Bioreactor for Engineered Bioartificial Tissues (BATS)

    SBC: Flexcell International Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Few commercial bioreactors are available for the culture of three dimensional (3D) tissues. Flexcell's strategy is to provide a commercial bioreactor allowing ease of operation to produce molded 3D tissue constructs in cell- populated matrix gels of variable geometries with controlled nutrient perfusion and mechanical stimulation. This design is based on a vali ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Miniature digital telemetric bioelectric recording

    SBC: BIO-SIGNAL GROUP CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): We will improve the radio component of an inexpensive, miniature battery-operated digital telemetric system (DT) for new applications in neuroscience. DT exploits commercially available digital audio integrated circuits and protocols to record, digitize, and transmit bioelectric signals without wires. Phase 1 is based on a prototype designed to record the activ ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Assay kit for microsomal triglyceride transfer protein

    SBC: Chylos, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Microsomal triglyceride transfer protein (MTP) is essential for apoB-lipoprotein assembly. MTP is typically studied using a multi-step radiolabel assay. Recently, we have developed a simple fluorescence assay for MTP. However, this assay needs special equipment and expertise in lipid biochemistry. Our aim is to simplify the assay and commercialize it in the for ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. A 3-D Robot Design to Overcome Arm Dysfunction in Stroke

    SBC: LAM DESIGN MANAGEMENT, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Disturbances in movement coordination are the least well understood but often the most debilitating with respect to functional recovery following stroke. These deficits in coordination are expressed in the form of abnormal muscle synergies and result in limited and stereotypic movement patterns that are functionally disabling. The result of these constraints i ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. A novel biotherapeutic expression platform in bacteria

    SBC: Viral Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall objective of the proposal is to develop a novel protein expression platform by capitalizing on the remarkable properties of the recently discovered twin-arginine translocation (Tat) pathway of bacteria. With over 300 therapeutic proteins currently in various stages of clinical trials, the road to a healthier future will require new methods for prod ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. ESA, a Novel Anti-inflammation Agent

    SBC: EVA PHARMACEUTICAL, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): We have discovered that Esculentoside A (EsA) has potent anti-inflammatory effects including specific COX2 inhibition. Our preliminary studies and the associated patent apply to the use of EsA for the prevention of radiation-related inflammation (IR). We found that EsA was more effective than Celebrex at preventing and reducing acute radiation dermatitis and l ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Real Time Risk of Mortality in Critically III Children

    SBC: Multivariate Algrithms, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The most important function of a pediatric intensive care unit (PICU) is to provide advanced computerized monitoring capabilities to clinicians to evaluate the clinical status of patients and to track their response to a wide range of interventions. We hypothesize that integrating and analyzing multiple, clinically important variables as: a. real time conti ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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