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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Microbial Surrogate Assay for Environmental PAH Exposure

    SBC: ARPHION LTD.            Topic: NIEHS

    DESCRIPTION (provided by applicant): Arphion is a company established to develop noninvasive products that will be used to diagnose, prevent, and treat head and neck and other cancers. 41,000 people are diagnosed with head and neck cancer (HNC) every yearin the United States, with 8,000 deaths. Tens of millions of people in the US are at increased risk for HNC due to exposure to the polycyclic ary ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Optimization of small molecule triazine antituberculars for in vivo efficacy

    SBC: COLLABORATIONS PHARMACEUTICALS, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Tuberculosis TB is due to infection with the pathogen Mycobacterium tuberculosis Mtb This disease represents a global health pandemic as based on WHO statistics it claims the lives of approximately million people per year while infecting nearly million New drugs are urgently needed with novel mechanisms of action that treat this disease while also ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Topically-delivered Targeted Gene Suppression of Immune Activation in Psoriasis

    SBC: Exicure, Inc.            Topic: NIAMS

    DESCRIPTION (provided by applicant): AuraSense Therapeutics (AST), along with Northwestern University, is applying a recently developed technology using oligonucleotide-functionalized nanoparticles (called spherical nucleic acids or SNAs) to control protein expression. These easily synthesized nanoparticles can have either DNA or RNA shells, and are less than 50 nm in hydrodynamic diameter. SNA co ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Developing a method to increase HIV testing among YMSM

    SBC: RESILIENT GAMES STUDIO, LLC            Topic: NICHD

    DESCRIPTION provided by applicant Adolescents are particularly vulnerable to HIV and account for one quarter of all new infections each year Most new infections among adolescents occur among young men who have sex with men YMSM Transmission of HIV can be virtually eliminated by treatment but testing rates are low and a significant proportion of YMSM are unaware of their HIV status P ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Mobile Augmented Screening Tool to Increase Adolescent HIV Testing and Linkage to Care

    SBC: Digital Health Empowerment, Inc            Topic: NICHD

    DESCRIPTION provided by applicant Adolescents face combined problems of increased HIV risk infrequent testing inconsistent linkage to care and a lack of prevention related knowledge We propose to address this by developing a Mobile Augmented Screening MAS tool that will increase youth HIV testing through the use of a tablet based intervention in clinica settings and then use text message ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Monochromatic 222 nm UV light: Development of a safe, cost-effective technology for the efficient reduction of bacterial and viral infection and transmission

    SBC: EDEN PARK ILLUMINATION, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Drug resistant bacteria such as MRSA and airborne transmitted microbes such as influenza and TB together present major health issues both in the developed and the developing world with major health care and economic consequences Recent research from Columbia University Medical Center demonstrated that single wavelength far UVC photons can kill bacteria a ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Memory Lane: A neuro-exergame to mitigate cognitive decline in later life

    SBC: 1ST PLAYABLE PRODUCTIONS LLC            Topic: NIA

    DESCRIPTION provided by applicant st Playable Productions and Union College propose to develop a commercializable product combining physical exercise and cognitive activities through interactive gaming on a stationary bicycle to help prevent cognitive decline and dementia in older adults The Interactive Physical and Cognitive Exercise System iPACES developed by Union Collegeandapos s Health ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. A Bullet Proof vascular graft to prevent dialysis access cannulation injury

    SBC: Innavasc Medical, Inc.            Topic: 400

    Project Summary Abstract Synthetic arteriovenous grafts AVGs can provide life sustaining vascular access for dialysis patients but are subject to multiple modes of failure and complications related to chronic needle cannulation poor graft identification delayed access and bleeding These graft needle cannulation associated complications translate to millions of dollars in health care expense ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Mobile Intervention Kit to Increase HIV/HCV Testing and Overdose Prevention Training

    SBC: Digital Health Empowerment, Inc            Topic: NIDA

    DESCRIPTION provided by applicant Because many people who inject drugs PWID do not receive adequate information about HIV or HCV testing and prevention or overdose prevention and response training we propose to develop a Mobile Intervention Kit to deliver technology based interventions from a library of theory guided video content The first iteration will address overdose prevention and r ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. DRUG DISCOVERY PLATFORM FOR PROTEIN ARGININE METHYLTRANSFERASE INHIBITORS

    SBC: CH3 BIOSYSTEMS, LLC            Topic: 300

    Project Summary Abstract The long term objective of this project is the generation of a universal drug discovery platform based on protein arginine methylation mechanisms involved in human disease The importance of protein arginine methylation in the context of human disease has become clear in the last few years with the realization that protein arginine methyltransferases and the target prot ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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