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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Non-ATP competitive inhibitors of cyclin dependent kinases as cancer therapeutics
SBC: PPI PHARMACEUTICALS, LLC Topic: NCIDESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Hepatitis C Virus RNA-Targeted Therapeutics
SBC: VIOGEN BIOSCIENCES, LLC Topic: NIAIDDESCRIPTION (provided by applicant): Hepatitis C virus (HCV) infection is a significant human health issue, accounting for 50% of liver transplants in the US, with approximately 170 million persons infected worldwide. The current standard of care therapy of PEGylated-interferon and ribavirin is effective in only about 50% of patients, with severe side effects and contraindications limiting patient ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A Millimeter-wave Tunable Cavity for Ultra-sensitive Solids and Liquids DNP-NMR at Low Budget
SBC: DOTY SCIENTIFIC, INC. Topic: NIA? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Selective activation of the vagus nerve as an improved therapy for heart failure
SBC: BLACKROCK MICROSYSTEMS, INC Topic: NHLBIDESCRIPTION (provided by applicant): The goal of the proposed project is to alleviate the enormous public health burden of heart failure. Heart failure leads to significant morbidity and mortality, affects almost five million Americans, and results in morethan 35 billion dollars in annual healthcare costs. Current pharmacological and surgical treatments are only moderately effective and can have s ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of Peptide Antibiotic Nucleic Acids
SBC: NUBAD LLC Topic: NIAIDDESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Clinical Text Automatic De-Identification to Support Large Scale Data Reuse and Sharing
SBC: Clinacuity, Inc Topic: 400DESCRIPTION provided by applicant The adoption of Electronic Health Record EHR systems is growing at a fast pace in the U S and this growth results in very large quantities of patient clinical data becoming available in electronic format with tremendous potentials but also equally growing concern for patient confidentiality breaches Secondary use of clinical data is essential to fulfill ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
PlusOne: Prototyping and Validation of a Wireless In-Home Breathing Monitor for Prevention of Overdose Deaths
SBC: Xandem Technology LLC Topic: NIDADESCRIPTION provided by applicant This proposal investigates the use of a novel passive personal monitoring system to stem the tide in the epidemic of deaths due to unintentional opioid drug overdoses In the U S in opioid drug overdoses including prescription pain relievers and heroin caused deaths a number that has increased dramatically over the past two decades A person w ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Novel mechanism for the treatment of epilepsy: New Vitamin K analogs target energetics and have low toxicity due to excellent specificity and low dose requirements compared to current therapies
SBC: NEUROENE THERAPEUTICS INC Topic: 106DESCRIPTION provided by applicant Epilepsy is the th most common neurological disorder with in people developing epilepsy the occurrence of more than one unprovoked seizure at some point in their lifetime Unfortunately of all patients have intractable medication resistant epilepsy Thus new anti epileptic drugs AEDs that target alternative mechanisms of action are needed ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Novel Dental Adhesives to Prevent Recurrent Caries
SBC: CuRE Innovations, LLC Topic: NIDCRDESCRIPTION provided by applicant Bacterial related marginal decay is the top reason for failure and retreatment of resin based composite restorations RBCs Retreatment of these restorations costs both the patients and insurance companies billions of dollars per year The weak point of the system is the zone known as the hybrid layer where the adhesive bonds the RBC to the dentin There are ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Empowering real time web based genomic big data analysis at commercial scale
SBC: FRAMESHIFT LABS INC Topic: 172DESCRIPTION provided by applicant The academic iobio project delivers web based applications that visualize and provide real time interactive analysis with multiple different data types generated as part of next generation sequencing projects These applications are open source and provided for free This proposal aims to develop critical computational infrastructure to enable the iobio project ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health