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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Microfluidic Viral Infection Assay

    SBC: Bellbrook Labs, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): In less than one year the 1918 Spanish flu pandemic claimed over 20 million lives worldwide, killing 675,000 Americans, more than 10 times the number of deaths to US servicemen in World War I. A similar strain of the vi rus that caused the 1918 pandemic could today kill 2 million Americans and force 10 million to be hospitalized. Although anti-viral drugs are k ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. VALIDATION AND QUANTIFICATION OF FFPE ANTIGEN RETRIEVAL BY PROTEOME ANALYSIS

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Because of the long history of the use of formalin as the standard fixative for tissue processing in histopathology, there are a large number of archival formalin-fixed and paraffin-embedded (FFPE) tissue banks worldwid e. These FFPE tissue collections, with attached clinical and outcome information, present invaluable resources for conducting retrospective pro ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  3. OVARIAN CANCER PROTEOME VIA TISSUE MICRODISSECTION AND GEMINI TECHNOLOGIES

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Biologically and clinically relevant proteomics data can only be generated if organ or tissue samples investigated consist of homogeneous cell populations, in which no unwanted cells of different types and/or developmen t stages obscure the results. Thus, several tissue microdissection technologies have been developed to provide a rapid and straightforward meth ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a low-cost hardware accelerator for 3D image registration.

    SBC: IGI TECHNOLOGIES, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Our overall goal is to develop a novel computing solution for automatic and accurate registration (spatial alignment) of three-dimensional (3D) medical images of any modality and any anatomy (rigid or deformable) in 1 m inute. Such capability currently does not exist. Existing image registration solutions have limited accuracy and/or limited applicability, prev ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  5. Comprehensive Genotyping for Susceptibility to Metabolic Muscle Disease

    SBC: JK AUTOIMMUNITY, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop a large-scale genotyping tool for metabolic muscle disease that can be applied to certain high risk groups in order to prevent life-threatening symptoms that are fast becoming a public health problem. The triggering of life-threatening metabolic muscle diseases by environmental factors such as drugs, viral infections, e ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  6. Multiplex Electroluminescent Assay for Detection of Hepatocellular Carcinoma

    SBC: MESO SCALE DIAGNOSTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of the proposed work is development of sensitive diagnostic serological assay panels for detection of hepatocellular carcinoma (HCC). Currently, the only biomarker used in HCC diagnosis is the measurement of al pha feto protein (AFP) in patient serum, which exhibits poor sensitivity and specificity. There is a need for alternative biomarkers to more ef ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Substance Abuse Diagnostic Clinical Interview Simulation

    SBC: SIMMERSION LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Traditional methods for training clinicians and students in mental health disciplines in substance abuse assessment have been restricted to role-playing, mock interviews, textbook lessons, and video instruction. All of these tools have limitations for imparting real world experiences. Specifically, traditional methods of instruction do not include realistic in ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  8. PRO-Surveyor: Device for Capturing Patient Reported Outcome Data in Children

    SBC: SPECTROCON, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Abstract Patient-reported outcomes (PROs) are a component of health-related quality of life that measure aspects of a patient's health that come directly from the patient, typically via the use of valid and reliable que stionnaires. Methods of administration are traditionally paper forms or computerized/internet methods. Each of these current methods has signif ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Cell-Based, Chronic Wound Gene Therapy for Older Adults

    SBC: Stratatech Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): To date no biological treatment options specifically targeting the proteolytic nature of chronic wounds have been developed and marketed. Chronic skin wounds constitute an important medical problem for the growing age d population. 18% of diabetic patients over the age of 65 suffer from chronic, non-healing foot ulcers, and it is estimated that over 50,000 lo ...

    STTR Phase II 2008 Department of Health and Human ServicesNational Institutes of Health
  10. a novel cardiovascular stent for the intrinsic reduction of restenosis and thromb

    SBC: VASCULAR PROFLIX, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): One-third of adults in the U.S. and throughout the world suffer from some form of cardiovascular disease (CVD). The use of bare-metal coronary stents (BMS) for the treatment of CVD increased by 147% from 1996 to 2000, s uch that 65-80% of treatments now involve stent implantation. Unfortunately restenosis limits the success of BMS in approximately 30-51% of pat ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
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