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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Bioscience Research Integration Software Platform

    SBC: BIOFORTIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The need to investigate and understand all elements of biological information pertinent to disease is more clearly evident now than ever before. However, the avalanche of non-integrated data produced by today's technologies prevents scientists from effectively reducing these data to meaningful discoveries. As a result, the vast bulk of data collected through ...

    STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  2. A Chaperonin/Osmolyte Protein Folding Screen- STTR Phase I

    SBC: EDGE BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): One of the largest bottlenecks in high-throughput protein structure determination (structural genomics) and in subsequent drug targeting (pharmocogenomics) is the acquisition of soluble correctly folded functional protein products. Unfortunately, a large amount of the protein expression systems that are commonly used yield insoluble or soluble misfolded protein ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  3. Long-term Ambulatory Gait Monitor for Parkinson's Disease

    SBC: IM SYSTEMS            Topic: N/A

    DESCRIPTION (provided by applicant): One of the primary and disabling clinical manifestations of Parkinson's disease (PD) is locomotor dysfunction, such as small, variable stride length and freezing of gait. Treatment of PD to a large extent focuses on replacing depleted dopamine at the striatum to maintain mobility for as long as possible. Clinical assessment relies on brief observation and frequ ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  4. Fieldtrip: Using Internet-Based Multi-Media to Engage Teens on Education Issues

    SBC: INFOCULTURE            Topic: N/A

    DESCRIPTION (provided by applicant): It is anticipated that only a third of today's high school students will go onto college despite consistent data that support the benefit of post-secondary education for individuals. Concurrently, daily Internet use among adolescents is nearing the fifty-percent mark, with broadband Internet steadily growing toward ubiquity. This project aims to leverage the ma ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. Lentiviral Redirected T Cells for B Cancer Immunotherapy

    SBC: LENTIGEN CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Our long term goal is to develop cellular based immunotherapy for the treatment of malignancy. One approach to enhancing the effects of cellular immunotherapy is via gene therapy. We are currently focused on enhancing the antitumor effects of adoptive T cell therapy using lentiviral vector-mediated genetic modification of cells to express a universal T cell rec ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  6. Samaritan Compounds Suppress Viral Replication and Prevent Neuronal Damage

    SBC: SAMARITAN PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Currently up to 50% of HIV infected individuals including those taking antiretroviral therapy have mild neurocognitive disorder. Furthermore, the population living with HIV infection continues to grow and there are now over one million people living with HIV in the US and 42 million around the world. This indicates that persistent HIV associated cognitive impai ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  7. Training Simulation to Teach Alcohol Screening and Brief Intervention

    SBC: SIMMERSION LLC            Topic: N/A

    Not avaiable.

    STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  8. Bio-Effects of Ultra-High MRI Gradient Slew Rates

    SBC: WEINBERG MEDICAL PHYSICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The spatial resolution and acquisition times for magnetic resonance imaging and spectroscopy could be improved through the application of more powerful and rapid magnetic gradients, thereby potentially leading to improv ed cardiac imaging and delineation and detection of cancers. Unfortunately, gradient field strength is limited by concerns about potential neur ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  9. Development of VPL Vaccine for RSV

    SBC: SIGMOVIR BIOSYSTEMS, INC.            Topic: NIAID

    Project Summary Human respiratory syncytial virus (RSV) is recognized as the single most important viral cause of acute respiratory disease in infants and young children worldwide. Elderly populations and immunocompromised individuals are also at significant risk for serious RSV disease. Despite this very substantial disease burden imposed by RSV worldwide, there are no vaccines available. Severa ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Non-ATP competitive inhibitors of cyclin dependent kinases as cancer therapeutics

    SBC: PPI PHARMACEUTICALS, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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