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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Development of an Autism Spectrum Disorder Screening Test based upon Metabolic Profiling of Fresh Blood Samples

    SBC: CIRCA BIOSCIENCE, LLC            Topic: 102

    Autism spectrum disorderASDis a neurodevelopmental disorder characterized by significant deficits in reciprocal social interactionsimpaired communication and restrictedrepetitive behaviorswith a prevalence ofinchildren in the USEarly intervention programs have been shown to be effective for improving IQlanguageand social skills for toddlers as young asmonths of ageDiagnosis of ASD is currently bas ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Dressing Assistant: Home Technology to Sustain Independent Dressing in Dementia

    SBC: Inventors' Workshops, Inc.            Topic: NIA

    AbstractPersons living with dementiaPWDoften require assistance with routine activities and daily tasksWorkloads placed on caregivers often results in high levels of physical and emotional stressand depressionand higher overall morbidity and mortality ratesFocus group of caregivers for individuals with mild to moderate dementiaidentified dressing the PWD as the most pressing and stressful daily co ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Enhanced Software Tools for Detecting Anatomical Differences in Image Data Sets

    SBC: Ligo Analytics            Topic: 105

    Project Summary Morphometric analysis is a primary algorithmic tool to discover disease and drug related effects on brain anatomy. Neurological degeneration and disease manifest in subtle and varied changes in brain anatomy that can be non-local in nature and effect amounts of white and gray matter as well as relative positioning and shapes of local brain anatomy. State-of-the-art morphometry meth ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Nucleobase aminosugars with reduced ototoxicity

    SBC: NUBAD, LLC            Topic: Y

    PROJECT SUMMARYAminoglycosides are one of the cheapest and well known antibiotics in clinical use for overyearsbut one of the major limitations in their use is their ototoxicityWe are developing fast and low cost methods to develop aminoglycosides with antiribosomal activities and reduced toxicityIn this projectwe will identify novel aminoglycoside antibacterialsthat show reduced ototoxicityComple ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. A software tool for objective identification of concussion-related vision disorders using a novel eye-tracking device

    SBC: Oculogica Inc            Topic: 102

    ABSTRACT This project will create the first objective measurement toolthe VisBoxfor the vision subtype of concussionVSCThis will enable physicians to identify VSC without an eye care professionalfor referral to a vision specialist for personalized vision therapy recommendationsThe persistence of concussion symptoms beyond several weeks is often a life altering situation for affected individualsand ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Emodin as a complementary dietary therapy to reduce toxicity of 5 fluorouracil

    SBC: AcePre, LLC            Topic: NCCIH

    PROJECT SUMMARYfluorouracilFUhas been the first choice chemotherapy drug for colorectal cancerCRCfor many yearshoweverits clinical utility remains hindered by hematopoietic and gastrointestinal toxicities resulting from its non selectivitySide effects include fatigueloss of appetiteand diarrhea among othersall of which can lead to reduced quality of lifeThe economic burden associated with chemothe ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Development of KLS-13019 for Chemotherapy Induced Peripheral Neuropathy and Drug Dependence

    SBC: KannaLife Sciences Inc.            Topic: NIDA

    Chemotherapy induced peripheral neuropathyCIPNcan be a chronicseverely debilitating consequence of cancer therapy for which there are no effective management strategiesMoreoverupwards ofof CIPN patients reported using prescription opioids for pain management despite the fact that there is only weak evidence that long term continuation of opioids provides clinically significant pain relief in these ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. MtLDL detection to diagnose childhood tuberculosis

    SBC: CHRONUS PHARMACEUTICALS, INC.            Topic: NIAID

    Project SummaryChildhood TB is estimated to contributeof the disease burden in high burden settingswith approximately a million cases per year inworldwideExisting gold standard diagnostic culture tools fail to confirm TB in most childrenwho typically have low bacterial counts and cannot produce sputumMore sensitive and child friendly diagnostic tools are urgently needed to diagnose TB in childrenC ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Targeting the sphingolipid pathway for the R&D of new antifungals

    SBC: MicroRid Technologies, Inc            Topic: NIAID

    ABSTRACT The goal of this project is to discover and develop a new therapeutic smore potent than current antifungals for the treatment of invasive fungal infectionsAmong invasive fungal infectionscryptococcosiscandidiasisand aspergillosis are the most life threateningThe incidence of these infections has risen more thanfold over the lastyearswith a mortality rate ofyearWe recently discovered a fun ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. A Novel Treatment for Acetominophen-Induced Liver Injury

    SBC: Mitotherapeutix LLC            Topic: 300

    Abstract The Specific Aim of this Phase I STTR proposal is to test the feasibility of blocking MCJalso called DnaJCto overcome acute acetaminophen liver toxicityAcetaminophen or APAPfrom acetyl paraaminophenolis a common drug used to address pain and feverIn the US aloneaboutpatients per year are admitted to intensive care units with APAP induced liver injury and close toof these patients undergo ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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