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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Preclinical evaluation of SERCA2 allosteric activators for pancreatic β-cell protection in diabetes.
SBC: NEURODON, LLC Topic: NIDDKThe overall goal of this collaborative project between Neurodon and Indiana University School of Medicine is the development of compounds that will offer disease-modifying treatments for type 1 (T1D) and type 2 diabetes (T2D) mellitus, a sorely unmet need. In this initial STTR project, we will use our expertise in medicinal chemistry, cell biology, and diabetes pathophysiology to functionally test ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Real-time Multimodal Diffuse Reflectance and Polarization Imaging Based Nerve Identification in Surgical Field of View
SBC: YAYA SCIENTIFIC LLC Topic: NIBIBPROJECT SUMMARY We propose to develop a novel non-contact, label-free multimodality imager that provides real-time intraoperative identification of nerves within the surgical field-of-view to facilitate the prevention of unintended nerve damage (termed iatrogenic nerve injury) during surgical procedures, as they are a major source of postsurgical complications, e.g., chronic pain. In the United St ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Optimizing Small Molecule Mechanomimetics to Treat Age-related Osteoporosis.
SBC: OAK RIDGE THERAPEUTIC DISCOVERY LLC Topic: NIAAbstract There is an unmet need to develop treatments for senile osteoporosis, a disorder characterized by an age-related reciprocal decrease in osteogenesis and increase in bone marrow fat. Senile osteoporosis resembles disuse osteopenia, suggesting its pathogenesis involves impaired bone mechanosensing. We discovered that the polycystin heterotrimeric complex (1PC1+3PC2) functions as a mechanose ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Novel Therapy for Hyperphosphatemic Familial Tumoral Calcinosis (hfTC) and Generalized Hyperphosphatemia
SBC: FGF Therapeutics INC. Topic: NIAMSAbstract Hyperphosphatemic familial tumoral calcinosis (hfTC) is a disease in which patients cannot produce the bioactive form of the hormone Fibroblast growth factor-23 (FGF23), which is secreted by osteocytes to rid the body of phosphate by acting on the kidney. hfTC is characterized by markedly elevated serum phosphate (Pi) which causes large intramuscular calcifications to develop. The calcifi ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Developing a selective TRPC3 ion channel inhibitor for epilepsy treatment
SBC: SEAK Therapeutics, LLC Topic: 106Project SummaryEpilepsy is one of the most common brain disorders. Current drugs have limited efficacy. Identifying new targeted drugs that can be used as safer, more effective therapies is in urgent unmet need. Selective inhibition of the transient receptor potential canonical 3 (TRPC3) emerges as a novel strategy to impede epilepsy. However, the currently best selective TRPC3 inhibitor, Pyr3, ha ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
TayCo Airborne Ankle Brace
SBC: TAYCO BRACE, INC. Topic: AFX23DTCSO1Ankle injuries are the second most common musculoskeletal injury in the military with service members being 5x more likely to sustain an ankle injury than the general population making it a leading cause of lost training and combat operation time. Airborn
STTR Phase I 2023 Department of DefenseAir Force -
Lightweight Multifunctional EMI-shielding Coatings Enabled by Domestic, Sustainable, & Low-Cost Carbon Nanotubes
SBC: SKYNANO LLC Topic: AFX23DTCSO1Electromagnetic Interface (EMI) Shielding is critical for maintenance of critical infrastructure and to prevent from external signals from disrupting electronics devices. State of the art EMI shielding includes heavy metal-based materials, which add mass
STTR Phase I 2023 Department of DefenseAir Force -
Domestic source of semiconducting carbon nanotubes for advanced chemical sensors
SBC: AMERICAN NANOTECHNOLOGIES INC Topic: AFX23DTCSO1Semiconducting carbon nanotubes (s-CNTs) have been used to build thin, flexible sensors relevant to the DoD mission. These include both physical sensors, such as stress/strain and temperature sensors, and chemical sensors, such as biomarker or toxic compo
STTR Phase I 2023 Department of DefenseAir Force -
Machine Learning-aided Multiscale Modeling of Fatigue Damage in Composite Structures
SBC: ANALYSWIFT, LLC Topic: X22DOTCSO1AFRL recently completed a project on determining the technical feasibility of new damage tolerance design approaches for composite aircraft structures. However, the average error for blind static strength predictions was 20%, while that for blind fatigue strength predictions was 40%. To realize Air Force’s vision of service life prediction, we need to predict the remaining fatigue life of compos ...
STTR Phase I 2023 Department of DefenseAir Force -
A New Rapid Conversion Technology for High Volume, Low Cost Carbon Fiber
SBC: ReMaxCo Technologies, LLC Topic: AF21ATCSO2Carbon fiber is now used extensively in military vehicles, structures and equipment, and its use will only expand due to its combination of light weight and high strength. However, the challenge of widespread adoption both in the military and in the comme
STTR Phase I 2022 Department of DefenseAir Force