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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A cloud based software platform to enhance reproducibility collaboration and translation of stem cell research

    SBC: Cellara, LLC            Topic: 400

    Project Summary Stem cell research has shown great potential to help treat or even cure a wide array of health conditions including cardiovascular and neurological disease cancer and diabetes This field is now beginning to move rapidly from the re search stage to clinical translation and commercial applications However it has been widely recognized that stem cell scientists have difficulty ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. A Nanotechnology-Based Hydrogen Generator for a Compact Fuel Cell Power System

    SBC: MAINSTREAM ENGINEERING CORPORATION            Topic: A08T009

    Advances in microelectronics technology have digitized the modern battlefield by enabling night vision, global positioning, laser range-finding/targeting, digital communications, and advanced sensing. As these powerful new battlefield technologies emerge and mature, the need for compact, efficient, silent, and safe power generation will continue to increase. While fuel cells have kept pace with th ...

    STTR Phase I 2008 Department of DefenseArmy
  3. A Novel Strategy to Identify Substances that Improve Mitochnodrial Fitness

    SBC: CYTEGEN CORP            Topic: NIA

    Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A Randomized Blinded Placebo Controlled Clinical Trial to Evaluate Longeveron Mesenchymal Stem Cell LMSC Therapy for Treating The Metabolic Syndrome

    SBC: Longeveron LLC            Topic: NIA

    The metabolic syndrome MetS is a cluster of factors that increases the risks for cardiovascular disease type diabetes mellitus and mortality and currently affects andgt of US adults MetS is associated with endothelial dysfunction decreased circulating endothelial progenitor cells EPCs and a pro inflammatory state We have made the exciting discovery that therapy with allogeneic me ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Additive Manufacturing of Multifunctional Nanocomposites

    SBC: Sciperio, Inc.            Topic: A13AT010

    Sciperio with team members Georgia Institute of Technology and Centecorp have teamed up to develop an Additive Manufacturing Composite using nano and micro fillers. The team will develop multi-scale models that are supported by experimental characterization for advanced 3D Printable materials. Inelastic response of high strength hierarchical structures composed of engineered materials and specif ...

    STTR Phase I 2013 Department of DefenseArmy
  6. AHTP-comet: development of an automated, high throughput comet assay system

    SBC: Engineering Resources Group, Inc            Topic: NIEHS

    PROJECT SUMMARY Genomic instabilityinduced by DNA damageand partly mitigated by DNA repair and antioxidantsplays a critical role in the pathogenesis of many major human diseasessuch as neurodegenerationcancer and cardiovascular diseasetogether with agingThere is a critical need for automated assays that can perform these assessmentsand bring them into greater routine usewhich will help advance our ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A novel asthma drug candidate targeting the GABAergic system in lung inflammation

    SBC: PANTHERICS INCORPORATED            Topic: NHLBI

    The proposed research will advance preclinical characterization and validation of a novel drug for asthmaA growing body of research has uncovered functional gamma amino butyric acid type A receptorGABAARsignaling in non neuronal cellsOur research has demonstrated that ligands activating GABAAR subtypes located on airway smooth muscle and immune cells reduce airway hyper responsivenessAHRand inflam ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. A Randomized, Blinded, Placebo-Controlled Clinical Trial to Evaluate Longeveron Mesenchymal Stem Cell (LMSC) Therapy for Treating The Metabolic Syndrome

    SBC: Longeveron LLC            Topic: NIA

    The metabolic syndromeMetSis a cluster of factors that increases the risks for cardiovascular diseasetypediabetes mellitusand mortalityand currently affects andgtof US adultsMetS is associated with endothelial dysfunctiondecreased circulating endothelial progenitor cellsEPCsand a pro inflammatory stateWe have made the exciting discovery that therapy with allogeneic mesenchymal stem cellsMSCsrestor ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Assessment of Team Competencies

    SBC: FLORIDA MAXIMA CORP            Topic: N/A

    The military's traditional reliance on teams to perform vital missions has become even more pronounced as the military transforms itself into a lighter, more mobile, and more deployable force. Although the military does an exceptional job of imparting thetechnical skills that are required for mission performance, considerably less progress has been made in understanding other factors that make a

    STTR Phase II 2001 Department of DefenseArmy
  10. Assessment of Team Competencies

    SBC: FLORIDA MAXIMA CORP            Topic: N/A

    The military's traditional reliance on teams to perform vital missions has become even more pronounced as the military transforms itself into a lighter, more mobile, and more deployable force. Although the military does an exceptional job of imparting thetechnical skills that are required for mission performance, considerably less progress has been made in understanding other factors that make a

    STTR Phase I 2001 Department of DefenseArmy

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