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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A cloud based software platform to enhance reproducibility collaboration and translation of stem cell research

    SBC: Cellara, LLC            Topic: 400

    Project Summary Stem cell research has shown great potential to help treat or even cure a wide array of health conditions including cardiovascular and neurological disease cancer and diabetes This field is now beginning to move rapidly from the re search stage to clinical translation and commercial applications However it has been widely recognized that stem cell scientists have difficulty ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. A Novel Approach to Purifying iPSC Derived Cell Cultures

    SBC: HocusLocus Inc.            Topic: 200

    DESCRIPTION provided by applicant We are pioneering an RNA based switch technology called structurally interacting RNAs sxRNA which utilizes post transcriptional gene regulation as a reporter for miRNA detection Normally RNA binding proteins RBP associate with a andapos stem loop structure to facilitate translation of an upstream coding region by as much as an order of magnitude It is ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. A NOVEL OXYGEN SEPARATION AND STORAGE APPARATUS FOR UNDERWATER AND HIGH ALTITUDE FUEL CELL APPLICATIONS

    SBC: Enogetek, Inc.            Topic: A08T011

    U.S. Military operations have come to depend more and more on unmanned vehicles (unmanned undersea vehicles UUVs and unmanned air vehicles UAVs) to carry out numerous missions. However, the transit distance for many of these missions is often well limited by the energy storage capacity of their power systems. Fuel cell, particularly SOFC that can be fed directly with reformate, looks promising. Co ...

    STTR Phase I 2008 Department of DefenseArmy
  4. A NOVEL OXYGEN SEPARATION AND STORAGE APPARATUS FOR UNDERWATER AND HIGH ALTITUDE FUEL CELL APPLICATIONS

    SBC: Enogetek, Inc.            Topic: A08T011

    U.S. Military operations have come to depend more and more on unmanned vehicles (unmanned undersea vehicles UUVs and unmanned air vehicles UAVs) to carry out numerous missions. However, the transit distance for many of these missions is often well limited by the energy storage capacity of their power systems. Fuel cell, particularly SOFC that can be fed directly with reformate, looks promising. Co ...

    STTR Phase II 2011 Department of DefenseArmy
  5. A novel product for tendinopathy treatment

    SBC: NEW YORK R&D CENTER FOR TRANSLATIONAL MEDICINE AND THERAPEUTICS, INC.            Topic: NIA

    Project Summary This study aims to prove the concept and feasibility that TendonCure extracellular vesicles that contain signaling molecules i e exosomes secreted by mesenchymal stem cells i e tendon stem progenitor cells TSPCs or adipose derived stem cells ADSCs from individual patients donors cultured on a novel scaffold exert therapeutic efficacy on tendinopathy when injected into ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. A Novel Strategy to Identify Substances that Improve Mitochnodrial Fitness

    SBC: CYTEGEN CORP            Topic: NIA

    Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. AlInGaN-based Dual Ultraviolet/Infrared Detectors

    SBC: Sensor Electronic Technology, Inc.            Topic: N/A

    We propose to develop dual infra-red UV solar-blind AlInGaN-based photodetectors by combining our novel Strain/Energy Band Engineering (SEBE) technology, selective area growth technique, and device passivation for the leakage current reduction with theMultiple Quantum Well design for using intersubband transitions for the infrared detection and band-to-band transitions for the UV detection.Dual an ...

    STTR Phase I 2001 Department of DefenseArmy
  8. An Integrated Hardware-Software Platform for Real-Time Modeling and Simulation of TMACNs

    SBC: Advanced Acoustic Concepts, Inc.            Topic: A06T008

    The Army’s Future Combat System will rely on a data communications backbone based on the tactical mobile ad-hoc communications network (TMACN). The unique nature of TMACNs – their mobility, adaptability, and potentially substantial sizes – makes performance prediction a difficult task, and one that is best carried out through simulation. The team of Advanced Acoustic Concepts and RTI Interna ...

    STTR Phase I 2006 Department of DefenseArmy
  9. A novel asthma drug candidate targeting the GABAergic system in lung inflammation

    SBC: PANTHERICS INCORPORATED            Topic: NHLBI

    The proposed research will advance preclinical characterization and validation of a novel drug for asthmaA growing body of research has uncovered functional gamma amino butyric acid type A receptorGABAARsignaling in non neuronal cellsOur research has demonstrated that ligands activating GABAAR subtypes located on airway smooth muscle and immune cells reduce airway hyper responsivenessAHRand inflam ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. A Novel remedy for periodontal bone loss

    SBC: Periomics Care LLC            Topic: NIDCR

    Abstract Periodontitis is a common chronic inflammatory disease characterized by destruction of the supporting structures of the teeththe periodontal ligament and alveolar boneThe total prevalence of periodontitis in adults agedyears and older wasrepresenting aboutmillion adults agedyears and olderandin adults agedyears and older in the U SEpidemiological data confirm that diabetes is a major risk ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health

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