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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. A cloud based software platform to enhance reproducibility collaboration and translation of stem cell research

    SBC: Cellara, LLC            Topic: 400

    Project Summary Stem cell research has shown great potential to help treat or even cure a wide array of health conditions including cardiovascular and neurological disease cancer and diabetes This field is now beginning to move rapidly from the re search stage to clinical translation and commercial applications However it has been widely recognized that stem cell scientists have difficulty ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. A Continuous Flow Liquid Cell Holder for the Transmission Electron Microscope

    SBC: Hummingbird Precision Machine Co.            Topic: A08T029

    Electron microscopy of specimen in liquid has recently been demonstrated by Niels de Jong at Oak Ridge National Laboratory (ORNL). A sample was enclosed in a liquid compartment with electron transparent windows and imaged using a scanning transmission electron microscope (STEM). Expanding on this expertise it is proposed to develop the technology of a liquid holder for both TEM and STEM that prov ...

    STTR Phase I 2008 Department of DefenseArmy
  3. A Novel Strategy to Identify Substances that Improve Mitochnodrial Fitness

    SBC: CYTEGEN CORP            Topic: NIA

    Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A Device to Inhibit Heterotopic Ossification

    SBC: IN SITU THERAPEUTIC SOLUTIONS INC            Topic: NIAMS

    PROJECT SUMMARY ABSTRACT Heterotopic ossificationHOis defined by bone formation in soft tissue and is a frequent debilitating complication of surgical procedures required by musculoskeletal and neurological injuriesUnfortunatelyit is not possible to accurately predict which patients will develop symptomatic HOwhich is characterized by pain and impaired functionThe current prophylactic standard of ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. A novel asthma drug candidate targeting the GABAergic system in lung inflammation

    SBC: PANTHERICS INCORPORATED            Topic: NHLBI

    The proposed research will advance preclinical characterization and validation of a novel drug for asthmaA growing body of research has uncovered functional gamma amino butyric acid type A receptorGABAARsignaling in non neuronal cellsOur research has demonstrated that ligands activating GABAAR subtypes located on airway smooth muscle and immune cells reduce airway hyper responsivenessAHRand inflam ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Automated Support for the da Vinci Surgical System

    SBC: MIMIC TECHNOLOGIES INC            Topic: A10AT029

    Over 1,400 da Vinci systems are in use worldwide and the install base grows by more than 350 robots each year. While adoption has been rapid, there exists a wide variance in performance of surgical procedures, which has had a negative impact on care quality, cost and patient safety. This is due in part to inefficient training practices and limited mechanisms for objectively assessing surgical p ...

    STTR Phase I 2010 Department of DefenseArmy
  7. Automated Support of Robotic Surgical Training, Operations, and Outcomes

    SBC: Spi Surgical, INC            Topic: A10AT029

    Background: Surgical error reduction requires addressing rapid adoption of new surgical technology. We propose development of a networked surgical assessment platform able to collect performance and outcomes data from multiple surgical platforms and sites for dynamic metrics analysis. Goal: Provide surgical signature ("Surgome") of each surgeon by delivering automated performance feedback to ...

    STTR Phase I 2011 Department of DefenseArmy
  8. Axonal Transport HTS Platform for Neurodegeneration Drug Discovery

    SBC: Bellbrook Labs, LLC            Topic: 106

    DESCRIPTION provided by applicant Neurodegenerative diseases that affect motor neurons such as PD ALS and HD represent an enormous unmet medical need that is growing with the aging population Existing treatments have little or no effect on the course of disease and patients have to cope with the loss of brain and body function for the rest of their lives Defects in the transport of organell ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Biological treatment of bacterial keratitis

    SBC: AMEBAGONE, INC.            Topic: N

    DESCRIPTION provided by applicant Staphylococcus is the most common cause of infections worldwide The pathogen persists asymptomatically on human skin from which it may spread to ocular tissues and cause corneal infection When this happens corneal bacterial keratitis can occur and if not treated effectively it may lead to blindness Multi Drug Resistant MDR variants of S aureus Sa are ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. CATALYTIC MEMBRANE REACTOR FOR THE PRODUCTION OF HYDROGEN FROM BUTANOL

    SBC: INNOVATEK, INC.            Topic: A10AT009

    A compact and efficient fuel processor that provides clean hydrogen from a high energy density liquid fuel such as butanol will allow fuel cell technology to be realized in military and commercial markets for portable applications. InnovaTek, and its proposal partner Indiana - Purdue University, will build on their combined experience in catalytic reforming to develop catalysts that are optimize ...

    STTR Phase I 2010 Department of DefenseArmy

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