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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Whole Tooth Tissue Engineering

    SBC: Dentigenix            Topic: N/A

    DESCRIPTION: The long-term objective of this project is to engineer biological tooth substitutes that can be used to replace missing, diseased or injured human teeth. The approach, based on recent successful tissue engineering efforts, is to seed single cell suspensions derived from immature tooth buds onto biodegradable polymer scaffolds, and to implant the seeded scaffolds in the omentum of rat ...

    STTR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  2. Web Based Therapist Training on Complicated Grief Therapy

    SBC: KOBAK, KENNETH A            Topic: 104

    Complicated Grief (CG) is a prevalent and debilitating disorder associated with significant distress and impairment. It differs from major depression in its treatment and symptomatology. CG is listed in DSM5 as a subtype of Trauma and Greif Disorder. The World Health Organization will include CG as a stand-alone disorder in ICD11, and it is expected that the DSM 5.1 subcommittee will follow suit. ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Wearable Shear Wave Tensiometry for Tracking Tendon Load during Dynamic Movement

    SBC: Design Concepts, Incorporated            Topic: NIAMS

    Project Summary The long term goal of this project is to develop a wirelesswearable system to estimate the tension in tendons of the legs during dynamic movementsTendon tension provides an estimate of muscle forcewhich is important information for understanding biomechanical behavior in all types of movementthough it has previously been difficult to measureRecent advances have shown that skin moun ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Wearable shear-wave tensiometry for tracking tendon load during dynamic movement

    SBC: Design Concepts, Incorporated            Topic: NIAMS

    Project Summary The goal of this project is to commercialize a wireless, wearable system to estimate the tension in superficial tendons throughout the limbs during dynamic movements. Tendon tension provides an estimate of muscle force, which is important information for understanding biomechanical behavior in all types of movement. Understanding muscle-tendon function inside the body is especially ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  5. UTERINE TUMOR TREATMENT USING HIGH INTENSITY ULTRASOUND

    SBC: SONIC CONCEPTS, INC.            Topic: N/A

    DESCRIPTION (provided by the applicant): High Intensity Focused Ultrasound (HIFU) offers a non-invasive, non-surgical, bloodless, outpatient treatment for uterine fibroid tumors. These tumors develop in over half of all women, and account for approximately 30 percent of all hysterectomies. This proposal will develop an integrated transvaginal HIFU probe and imaging transducer for fibroid treatment ...

    STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  6. UTERINE TUMOR TREATMENT USING HIGH INTENSITY ULTRASOUND

    SBC: SONIC CONCEPTS, INC.            Topic: N/A

    DESCRIPTION (provided by the applicant): High Intensity Focused Ultrasound (HIFU) offers a non-invasive, non-surgical, bloodless, outpatient treatment for uterine fibroid tumors. These tumors develop in over half of all women, and account for approximately 30 percent of all hysterectomies. This proposal will develop an integrated transvaginal HIFU probe and imaging transducer for fibroid treatment ...

    STTR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  7. Use of Microarray Test Data for Toxicogenomic Prediction

    SBC: YAHSGS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This project bridges the understanding between physical and chemical principles and genomic/proteomic response by integrating three independent parallel toxicity prediction tools. Each uses computational neural networks (CNNs) and wavelets to rapidly and accurately make pharmaceutical/chemical toxicity predictions. A CNN-based Quantitative Structure-Activity ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  8. Universal Exercise Kits for Manual Wheelchair Users

    SBC: Exerstrider Products, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Many people with lower extremity physical disabilities are denied access to participating in health-enhancing cardiovascular exercise because of a lack of accessible equipment. This Phase I project will design and validate lightweight, easily installed aftermarket accessory kits which convert the most popular cardiovascular exercise equipment (stationary exerc ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Ultra-Sensitive Diagnosis of AIDS-Related Tuberculosis

    SBC: AttoDx, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant This grant will develop a novel strategy to enhance the analytical sensitivity of polymerase chain reaction PCR based detection of bacteria in samples We will commercialize the strategy in the form of a pre PCR andquot turbo chargerandquot to be marketed in conjunction with PCR based molecular diagnostic systems The current STTR project will apply this str ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Translational development of specialized NK cells for cancer immunotherapy

    SBC: Indapta Therapeutic            Topic: 102

    Project Summary Abstract The annual incidence of head and neck cancers worldwide is more thancases with arounddeaths each yearand it is estimated that inthere will benew cases of non Hodgkin lymphoma with an estimateddeaths this yearIn this proposalwe describe a strategy to use a novel subset of natural killer cellsg NK cellsallogeneically for cancer therapyWe hypothesize that expansion and adopti ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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