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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. A Device to Inhibit Heterotopic Ossification

    SBC: IN SITU THERAPEUTIC SOLUTIONS INC            Topic: NIAMS

    PROJECT SUMMARY ABSTRACT Heterotopic ossificationHOis defined by bone formation in soft tissue and is a frequent debilitating complication of surgical procedures required by musculoskeletal and neurological injuriesUnfortunatelyit is not possible to accurately predict which patients will develop symptomatic HOwhich is characterized by pain and impaired functionThe current prophylactic standard of ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A novel asthma drug candidate targeting the GABAergic system in lung inflammation

    SBC: PANTHERICS INCORPORATED            Topic: NHLBI

    The proposed research will advance preclinical characterization and validation of a novel drug for asthmaA growing body of research has uncovered functional gamma amino butyric acid type A receptorGABAARsignaling in non neuronal cellsOur research has demonstrated that ligands activating GABAAR subtypes located on airway smooth muscle and immune cells reduce airway hyper responsivenessAHRand inflam ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. ASCEND, Accelerating Solutions for Commercialization and Entrepreneurial Development in the Mountain West IDeA States

    SBC: VIRTICI LLC            Topic: NIGMS

    Project Summary The objective of this proposal is to create a Mountain West region technology Accelerator Hub to conduct research on developingimplementingand testing a comprehensive collateral and consulting offering for promoting biomedical entrepreneurshiptechnology transfermanagementsmall business financeand additional business skills needed to commercialize basic research to enhance human hea ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Automated Health Assessment through Mobile Sensing and Machine Learning of Daily Activities

    SBC: Adaptelligence LLC            Topic: NIBIB

    PROJECT SUMMARY ABSTRACTAdvances in health care have been dramatic since the beginning of the millenniumAs a resultpeople are living longer with age related diseasesand the number of older individuals unable to live independently is rising rapidlyMobile computing offers an unprecedented opportunity to unobtrusively monitor behavior and use the large amount of collected data to automate analysis of ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Custom-Fit Personal Sound Amplification Smartphone Application

    SBC: ASCENDING HEARING TECHNOLOGIES, LLC            Topic: NIDCD

    PROJECT SUMMARYPersonal sound amplification productsPSAPshave recently become available to the publicPSAPs serve a potentially important role in providing audibility of sounds for adults who have difficulty hearing in some daily living situationsbut may not be candidates for traditionalhigh amplification hearing aidsFewer thanof adults with hearing loss reporting use of hearing aidsciting high cos ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Enabling dexterous surgery at the tip of a flexible endoscope: A low-cost, disposable, steerable sheath.

    SBC: EndoTheia, Inc.            Topic: NIBIB

    Project Summary AbstractThe objective of this proposal is to perform proof of concept experiments for a new thin walledsteerable sheath that can pass through a standard colonoscope port and dexterously maneuver surgical instruments at its tipClinical significance comes from the fact that overpatients per year in the USA have unnecessaryinvasive surgery to remove a section of their colonClinical li ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Fully Human Antibodies for the Prevention of Respiratory Syncytial Virus

    SBC: IDBiologics, Inc.            Topic: NIAID

    The goal of this STTR is to provide a preclinically validated monoclonal antibody or antibody combination for the prevention of respiratory syncytial virusRSVin high risk patients including infants and the elderlyWorldwideof children are infected with RSV before the age ofresulting in an estimatedmillion lower respiratory tract infectionsIn the United States adults overhavemillion RSV infections c ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Fully Human Antibody Combinations for the Prevention of Seasonal Influenza Infection

    SBC: IDBiologics, Inc.            Topic: NIAID

    Our overarching goal is to develop a monoclonal antibody based product for the prevention of seasonal influenza in high risk patientsIt is estimated there aredeaths annually related to seasonal influenza worldwideIn the United Statestheinfluenza season was classified a high severity season withdeathsandhospitalizations attributed to influenzaserving as a reminder of the continued severity of influ ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Mobile-phone integrated rapid diagnostic tests to improve antibiotic stewardship

    SBC: PragmaDx, Inc.            Topic: NIAID

    PROJECT SUMMARYAn estimatedbillion antibiotic prescriptions were filled in the US fromDespite a national antibiotic education campaignapproximatelyof antibiotic prescriptions are unnecessaryAs a result of the over prescription of antibioticsthere is a current and pressing public health need for improved antibiotic stewardshipCompounding this problem are new modalities of healthcare like telemedici ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. PIXUL-FFPE:High throughput platform for chromatin and DNA sample preparation from formalin fixed paraffin embedded (FFPE) tissue samples.

    SBC: Matchstick Technologies Inc.            Topic: 172

    Formalin fixed paraffin embeddedFFPEtissue archives represent the largest clinically annotated human specimen repositoryThe estimated millions of available FFPE tissue samples provide vast resource for the discovery of disease epigenetic pathwaysbiomarkers and drug targetsAnd yetthese samples are highly underutilized because current methods for extracting molecular information from FFPE samples ar ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health

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