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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A biochemical companion diagnostic platform to measure kinase inhibitor pharmacodynamics in leukemia

    SBC: MICROFLUIDIC INNOVATIONS, LLC            Topic: 102

    DESCRIPTION provided by applicant Kinase inhibitors created a new paradigm in chemotherapy and are a major focus of new oncology drug development The Bcr Abl inhibitor imatinib was a breakthrough drug for chronic myelogenous leukemia with overwhelming early results however at least of patients are either intolerant resistant or experience recurrence within years and individual respo ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. A new generation of targeted therapeutics for the treatment of cancer

    SBC: NERX BIOSCIENCES, INC.            Topic: NCI

    DESCRIPTION provided by applicant Development of novel lung cancer therapeutics targeting the DNA damage response Abstract Lung tissue is constantly exposed to a wide variety of inhaled chemical agents While the majority of these maybe innocuous those that damage DNA have severe consequences Thus the DNA damage response DDR and DNA repair in these tissues is extremely important The vast ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. A Novel Probiotic Platform to Treat Necrotizing Enterocolitis

    SBC: Monon Bioventures LLC            Topic: 300

    PROJECT SUMMARY Probiotics hold enormous potential for promoting human health and treating disease One major hurdle to many probiotic products is their lack of persistence in the gut Monon Bioventures MBV and their research partners at the Research Institute at Nationwide Childrenandapos s Hospital RINCH are developing a novel enhanced tunable technology called ProNextTM that allows for a ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. A simple assay system for rapid detection of circulating tumor cells

    SBC: TELOVISION, LLC            Topic: NCI

    DESCRIPTION provided by applicant Metastasis or dissemination of primary tumor cells is the major cause of mortality in cancer patients Circulating tumor cells CTCs in the bloodstream are key players in the establishment of metastatic tumors Recent studies demonstrated that the number of CTCs present in patient blood directly correlate with cancer progression recurrence and survival rate ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Biodegradability and Biocompatibility of a Shape Memory Polymer Wrap to Improve Saphenous Vein Graft Patency in Peripheral and Coronary Artery Bypass Grafting Surgeries

    SBC: VenoStent, Inc.            Topic: NHLBI

    PROJECT SUMMARY/ABSTRACT Peripheral artery disease (PAD) affects nearly 12 million people in the United States. One of the most common surgical therapies is peripheral artery bypass grafting (PABG). Some patients are eligible for less invasive treatment options like angioplasty, but patients with calcified lesions are not. In patients that do receive PABG, approximately 20% fail within the first y ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  6. CNT Based Microstrip Plasma Limiter

    SBC: ACCURATE AUTOMATION CORPORATION            Topic: MDA10T001

    Accurate Automation Corporation will develop a carbon nanotube based microstrip plasma limiter suitable for inclusion on RF printed circuit boards used on the front-end of an X-Band phased-array receiver. This device will capitalize on the ability to use carbon nanotubes to reduce the size and cost of an RF limiter while dramatically increasing the performance. Specific attention will be focused o ...

    STTR Phase I 2011 Department of DefenseMissile Defense Agency
  7. Corrosion Protection of High-Value Test&Evaluation Assets

    SBC: eSpin Technologies, Inc.            Topic: MDA13T010

    This STTR Phase I proposal proposes to design and develop reactive filter media using nanofiber technology to capture corrosion inducing particulate matter present in coastal region air. The fibrous filter media will be functionalized using ion exchange chemistry which is known to react with salt ions. The media will be characterized for its filtration performance, resistance to airflow, and dus ...

    STTR Phase I 2014 Department of DefenseMissile Defense Agency
  8. Develop and/or Improve Optical Coating Processes for Military Mirrors

    SBC: FLEXIAL CORP.            Topic: N/A

    Develop a titanium, welded metal bellows extendable sunshade to deploy over seeker system optics in kinetic kill vehicles and other military missile systems that employ optical tracking. One object of the sunshade is to offer an alternative technology tohelp improve the durability of optical coatings by minimizing thermal gradients on the coatings as would be generated by free airflow across the ...

    STTR Phase I 2003 Department of DefenseMissile Defense Agency
  9. Develop and/or Improve Optical Coating Processes for Military Mirrors

    SBC: FLEXIAL CORP.            Topic: N/A

    A space-saving, economical, collapsible alternative to rigid sunshades-and particularly a replacement for beryllium sunshades-for the protection of optical coatings and heat seeking sensors on kinetic kill vehicles and similar equipment. The bellows sunshade is a self-deploying, non-toxic, titanium, all metallic, non-outgassing cylindrical shield that can expand up to twelve times its stowed leng ...

    STTR Phase I 2004 Department of DefenseMissile Defense Agency
  10. Develop and/or Improve Optical Coating Processes for Military Mirrors

    SBC: FLEXIAL CORP.            Topic: MDA03T003

    A space-saving, economical, collapsible alternative to rigid sunshades-and particularly a replacement for beryllium sunshades-for the protection of optical coatings and heat seeking sensors on kinetic kill vehicles and similar equipment. The bellows sunshade is a self-deploying, non-toxic, titanium, all metallic, non-outgassing cylindrical shield that can expand up to twelve times its stowed leng ...

    STTR Phase II 2004 Department of DefenseMissile Defense Agency
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