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SUMMARY Sepsis is a clinical syndrome that complicates severe infectionSepsis remains the leading cause of morbidity and mortality in critically ill patientsThere are no specific FDA approved medicines for the treatment of sepsisCurrent concepts of the pathophysiology of sepsis suggest that organ failure and mortality in sepsis are caused by inappropriate regulation of the immune systemThis manife ...

"Building upon Fraunhofer Center's recently developed process of producing reactive nanoparticles (e.g., metals, carbides and nitrides) at high rates in a pristine environment, and Nanopowder Enterprises Inc.'s technology of dispersing nanoparticlesuniformly as a second phase in a polymer matrix, we propose to develop a generic technology for fabricating polymer nanocomposites, wherein the dispers ...

Quality assurance QA is a critical component of radiation oncology that ensures both effective treatment delivery and patient safety Over the last decade dQA is now particularly important asramatic innovations in treatment delivery technologiesy have led to increasingly sophisticated and complex treatments that are difficult to adequately verify with conventional dosimetric verification system ...

Accurate Automation Corporation will develop a carbon nanotube based microstrip plasma limiter suitable for inclusion on RF printed circuit boards used on the front-end of an X-Band phased-array receiver. This device will capitalize on the ability to use carbon nanotubes to reduce the size and cost of an RF limiter while dramatically increasing the performance. Specific attention will be focused o ...

This STTR Phase I proposal proposes to design and develop reactive filter media using nanofiber technology to capture corrosion inducing particulate matter present in coastal region air. The fibrous filter media will be functionalized using ion exchange chemistry which is known to react with salt ions. The media will be characterized for its filtration performance, resistance to airflow, and dus ...

Develop a titanium, welded metal bellows extendable sunshade to deploy over seeker system optics in kinetic kill vehicles and other military missile systems that employ optical tracking. One object of the sunshade is to offer an alternative technology tohelp improve the durability of optical coatings by minimizing thermal gradients on the coatings as would be generated by free airflow across the ...

A space-saving, economical, collapsible alternative to rigid sunshades-and particularly a replacement for beryllium sunshades-for the protection of optical coatings and heat seeking sensors on kinetic kill vehicles and similar equipment. The bellows sunshade is a self-deploying, non-toxic, titanium, all metallic, non-outgassing cylindrical shield that can expand up to twelve times its stowed leng ...

A space-saving, economical, collapsible alternative to rigid sunshades-and particularly a replacement for beryllium sunshades-for the protection of optical coatings and heat seeking sensors on kinetic kill vehicles and similar equipment. The bellows sunshade is a self-deploying, non-toxic, titanium, all metallic, non-outgassing cylindrical shield that can expand up to twelve times its stowed leng ...

In response to SBIR topic MDA09-T006, USCI proposes to develop the first medium-level integrated circuit for radiation-tolerant applications. The advanced integrated circuit will be demonstrated based on a novel yet simple design SiC transistor that has the potential to provide a factor of 10X improvement in performance comparison to state-of-the-art. The SiC transistor can be fabricated by a subs ...

Project Summary AbstractThe objective of this proposal is to perform proof of concept experiments for a new thin walledsteerable sheath that can pass through a standard colonoscope port and dexterously maneuver surgical instruments at its tipClinical significance comes from the fact that overpatients per year in the USA have unnecessaryinvasive surgery to remove a section of their colonClinical li ...