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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A Cloud based Application for the Joint Analysis of Multiple Big Data Types

    SBC: MathNimbus Inc            Topic: 400

    Project Summary Technology advances now enable the cost effective acquisition of Kandgt distinct data types from a common set of N bio samples where i the kth data type is represented by a data matrix with columns containing Pk measurements in N samples for k K and ii at least one of the data types is big i e Pk is much bigger than N for some k The rapid accumulation of such mult ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. ADVANCED NITRIDE-BASED MATERIALS AND STRUCTURES FOR HIGH-PERFORMANCE ELECTRONICS

    SBC: MAGELLUS CORP.            Topic: N/A

    "This proposal discusses materials and related device research in the area of wide-bandgap compound semiconductors in the III-N system. The major tasks involve the growth of AlGaN/GaN heterojunction device structures and the development of improvedmaterials. These devices are important for a wide variety of high-performance electronic systems, including high-power and high-frequency microwave an ...

    STTR Phase I 2002 Department of DefenseMissile Defense Agency
  3. Advanced Rocket Trajectory Propagation Techniques

    SBC: NANOHMICS INC            Topic: MDA17T002

    High-fidelity trajectory propagators are fundamental to the simulation and analysis of launch vehicles, missiles, and satellites. Applications in fields ranging from missile threat analysis to flightpath optimization seek fast and accurate solutions to large numbers of trajectories in federated simulation environments. Due to their robustness, well-known properties, and straightforward implementat ...

    STTR Phase I 2018 Department of DefenseMissile Defense Agency
  4. Advance Early Detection of Lupus Nephritis with ClearGold

    SBC: CLEARNANO INC            Topic: 400

    SummarySystemic lupus erythematosusSLEor lupus is an autoimmune disease that impacts more thanmillion people worldwideincludingmillion AmericansNearlyof these patients will develop lupus nephritiswhich can cause kidney failureAs a resultits financial burden to individual patient can reach $yearmuch higher than many other diseases because of kidney transplantationAlthough early treatment of lupus n ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. A Generalized Data Driven Prognostic Algorithm Based On A Kalman Filter Mixture-Of-Experts Framework

    SBC: E-Spectrum Technologies, Inc.            Topic: N/A

    This research is centered on the investigation of a modular methodology for application of adaptive Kalman filtering using a mixture-of-experts network to a data driven prognostic system for the Airborne Laser (ABL). In this framework, each expert nodewill be a Kalman filter modeled with failure modalities based on physical ABL system parameters. This framework provides the robust on-line progno ...

    STTR Phase I 2003 Department of DefenseMissile Defense Agency
  6. A high-efficiency, low-cost, single-use purification technology for therapeutic antibody manufacturing

    SBC: Bondwell Technologies Inc.            Topic: 400

    Therapeutic antibodies have had a profound impact on treatment of many types of cancer and autoimmune diseasesAs a resultfive of the top ten best selling drugs ofwere therapeutic antibodiesMore than seventy therapeutic antibodies have been approvedand over six hundred antibody based products are in clinical developmentHoweverantibodies are extremely expensive to produceand large amounts of antibod ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. AIMSMART: Adaptive, Interactive MDA Semantic Model-based Articulation

    SBC: CYCORP, INC.            Topic: MDA11T003

    We will develop automatic ontology-aligning software, leveraging the enormous existing Cyc AI system to drive the formulation and ranking (pro/con argumentation) of hypotheses about term-term relationships, especially where the relationship is not simple 1-to-1 correspondence. Multiple Cyc micro-theories (contexts) will be created, to hold incommensurate alternative mappings, and logical conseque ...

    STTR Phase II 2013 Department of DefenseMissile Defense Agency
  8. AIMSMART: Adaptive, Interactive MDA Semantic Model-based Articulation of Required Technology for M&S

    SBC: CYCORP, INC.            Topic: MDA11T003

    The process of an MDA stakeholder specifying a needed modeling and simulation system has many problems: they may be ambiguous, overly specific, overly general, contradictory, etc. Symbolic knowledge-based representation and reasoning systems have matured to the point where they can ameliorate this. E.g., an extension of Cyc can help a Marines ISR-E requirements officer prepare a JCIDS CDD needs ...

    STTR Phase I 2012 Department of DefenseMissile Defense Agency
  9. A Low-Cost, Laboratory-Scale Method to Identify Regions of Microstructural Changes in Response to Dynamic Loading Conditions

    SBC: McConnell Jones Lanier & Murphy LLP            Topic: MDA16T003

    This proposal outlines a plan to develop an innovative and effective laboratory based method to support first-principles modeling of structural material responses under a range of energetic loadings, including explosions and high velocity impact. The range of strain rates posed by these dynamic loadings is similar to that experienced in metals in advance of a cutting tool. This provides a low-co ...

    STTR Phase I 2017 Department of DefenseMissile Defense Agency
  10. Aminooxyacetic Acid Prodrugs for Colon Cancer Therapy

    SBC: CBS THERAPEUTICS, INC.            Topic: 102

    ABSTRACT Recent studies of the applicants support the role of the endogenous gaseous biological mediator hydrogen sulfide H S in colorectal cancer In specific the selective upregulation of cystathionine synthase CBS and the subsequent production of H S in colonic cancer cells serves as a pro survival factor by stimulating tumor cell bioenergetics ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
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