List

Project Summary Stem cell research has shown great potential to help treat or even cure a wide array of health conditions including cardiovascular and neurological disease cancer and diabetes This field is now beginning to move rapidly from the re search stage to clinical translation and commercial applications However it has been widely recognized that stem cell scientists have difficulty ...

Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...

DESCRIPTION provided by applicant Neurodegenerative diseases that affect motor neurons such as PD ALS and HD represent an enormous unmet medical need that is growing with the aging population Existing treatments have little or no effect on the course of disease and patients have to cope with the loss of brain and body function for the rest of their lives Defects in the transport of organell ...

DESCRIPTION provided by applicant Staphylococcus is the most common cause of infections worldwide The pathogen persists asymptomatically on human skin from which it may spread to ocular tissues and cause corneal infection When this happens corneal bacterial keratitis can occur and if not treated effectively it may lead to blindness Multi Drug Resistant MDR variants of S aureus Sa are ...

Accurate Automation Corporation will develop a carbon nanotube based microstrip plasma limiter suitable for inclusion on RF printed circuit boards used on the front-end of an X-Band phased-array receiver. This device will capitalize on the ability to use carbon nanotubes to reduce the size and cost of an RF limiter while dramatically increasing the performance. Specific attention will be focused o ...

This STTR Phase I proposal proposes to design and develop reactive filter media using nanofiber technology to capture corrosion inducing particulate matter present in coastal region air. The fibrous filter media will be functionalized using ion exchange chemistry which is known to react with salt ions. The media will be characterized for its filtration performance, resistance to airflow, and dus ...

Develop a titanium, welded metal bellows extendable sunshade to deploy over seeker system optics in kinetic kill vehicles and other military missile systems that employ optical tracking. One object of the sunshade is to offer an alternative technology tohelp improve the durability of optical coatings by minimizing thermal gradients on the coatings as would be generated by free airflow across the ...

A space-saving, economical, collapsible alternative to rigid sunshades-and particularly a replacement for beryllium sunshades-for the protection of optical coatings and heat seeking sensors on kinetic kill vehicles and similar equipment. The bellows sunshade is a self-deploying, non-toxic, titanium, all metallic, non-outgassing cylindrical shield that can expand up to twelve times its stowed leng ...

A space-saving, economical, collapsible alternative to rigid sunshades-and particularly a replacement for beryllium sunshades-for the protection of optical coatings and heat seeking sensors on kinetic kill vehicles and similar equipment. The bellows sunshade is a self-deploying, non-toxic, titanium, all metallic, non-outgassing cylindrical shield that can expand up to twelve times its stowed leng ...

DESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...