Award Data

In this STTR, OASIS Inc, with partners the Massachusetts Institute of Technology (MIT) and the Applied Physics Laboratory University of Washington (APL-UW) proposes to develop an innovative, interactive submarine acoustic counter detect TDA for use by the Submarine Mission Planners, within the AN/BYG-1. Communicating the environmental and tactical uncertainty is of primary importance when present ...

Missile defense takes place in an uncertain and dynamic environment, so multi-sensor fusion must be employed to aggregate and merge disparate data from the battlefield. However, the fusion process is hindered by the vast amount of uncertainty in operational contexts, such as imprecise measurements and varying environmental conditions. Various algorithms and fusion processes have been developed to ...

DESCRIPTION provided by applicant Cancer is the second leading cause of death after heart disease in the US Chemotherapy is a mainstay of treatment after surgical removal of tumors but the balance of clinical benefit versus disabling or life threatening side effects is often uncertain Genotyping of cancers to identify mutated oncogenes has enabled an era of targeted therapy Drugs targeting ...

The objective of this project is to evolve the RF device ontology developed in Phase I, design and implement a run time prototype system, develop a test environment and perform an evaluation of the approach developed in Phase I. Based upon the findings and success of Phase I, we propose to continue the work on the Dev2WALDO ontology, augment it with necessary concepts, design and develop a prototy ...

DESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) and the Surgical Navigation and Robotics Laboratory (SNR) at Brigham and Women's Hospital (BWH) propose to develop and test a Smart Template to guide transperineal targeted prostate biopsiesand subsequent therapy under magnetic resonance imaging (MRI). The project aims to solve the problem of poor diagnostic yield in prostate b ...

DESCRIPTION (provided by applicant): This project proposes to build an integrated software-based system for enhancing the accuracy of tumor change detection. The intent of the system, called AutoRegister, which is to be deployed on a clinical magnetic resonance imaging (MRI) scanner platform, is to automate the alignment of a patient's brain scan with that of a prior scan, such that subseque ...

DESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...

ABSTRACT: Close integration of photonic devices with silicon complementary metal-oxide semiconductor (CMOS) electronics can yield significant performance improvements in many applications. The recent development of novel integrated structures in silicon including waveguides, resonators, and photodetectors will enable dramatic reductions in size, weight, and power for components implementing compl ...

Physical Sciences Inc. and Colorado State University will develop an innovative sensor that enables low-cost infrared hyperspectral imaging though the use of novel sampling algorithms which provide real-world chemical plume detection capability with compressed data and a hardware configuration which enables high frame rate capture of full 2D spatial and 1D spectral data. Compressive sensing techn ...

This STTR Phase I proposal proposes to design and develop reactive filter media using nanofiber technology to capture corrosion inducing particulate matter present in coastal region air. The fibrous filter media will be functionalized using ion exchange chemistry which is known to react with salt ions. The media will be characterized for its filtration performance, resistance to airflow, and dus ...