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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Phase 1 Trial to Assess Safety and Immune Effects of Xenon Gas in Healthy Human Subjects
SBC: General Biophysics LLC Topic: NIAPHASE II APPLICATION(STTR Program PAS-22-197) “Phase 1 Trial to Assess Safety and Immune Effects of Xenon Gas in Healthy Human Subjects” ABSTRACTAlzheimer’s disease (AD) is one of the most prevalent neurodegenerative disorders. Emerging evidence shows that homeostatic dysregulation of the brain immune system, especially that orchestrated by microglia, plays a significant role in the onset an ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Molecular brush-conjugated antisense oligonucleotide as a pan-KRAS depletion agent
SBC: PACDNA LLC Topic: NCIProject Summary/Abstract Mutant forms of KRAS are a key driver in human tumors but remain partially refractory to therapeuticintervention. After over three decades of research, only a single inhibitor (sotorasib) targeting a singlemutation (KRASG12C) have reached market. The difficulty for developing small molecule KRAS inhibitorshas heightened the importance of alternative methods targeting the o ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Making Connections Thru Music: A Group Music Therapy-Based Intervention for Persons with Dementia
SBC: HOPEFUL AGING LLC Topic: RPROJECT SUMMARY/ABSTRACTHealthcare systems around the world, including within the United States, have long-established shortages of trained caregivers (WHO, 2016; Jones, Liu, Murfield, and Moyle, 2020). The American Health Care Association (2019) states that “the health care system has experienced a shortage of trained caregivers for critical roles for some time.” This scarcity directly impact ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Real-time Multimodal Diffuse Reflectance and Polarization Imaging Based Nerve Identification in Surgical Field of View
SBC: YAYA SCIENTIFIC LLC Topic: NIBIBPROJECT SUMMARY We propose to develop a novel non-contact, label-free multimodality imager that provides real-time intraoperative identification of nerves within the surgical field-of-view to facilitate the prevention of unintended nerve damage (termed iatrogenic nerve injury) during surgical procedures, as they are a major source of postsurgical complications, e.g., chronic pain. In the United St ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Developing novel technologies to monitor nociception and opioid administration during surgery and general anesthesia in order to minimize post-operative opioid requirements
SBC: PASCALL Systems, Incorporated Topic: NIDAPROJECT SUMMARY In light of the opioid crises, minimizing postoperative pain and postoperative opioid requirements to reduce chronic opioid dependency among surgical patients have become major concerns for surgeons and anesthesiologists. Effective intraoperative nociception control can mitigate these concerns. Unfortunately, existing nociceptive monitoring tools use indicators that are inherently ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Fast and Radiation Hard Scintillators for High Dose Detection
SBC: RADIATION MONITORING DEVICES, INC. Topic: DTRA20B001The event of nuclear explosion generates harsh radiation conditions, evaluation of which is critical in protecting the military and civilian personnel from serious harm. Due to these harsh conditions only very simple methods of radiation assessment are employed, such as measurement of equivalent dose. Improvements to current instrumentation are sought that would provide energy resolved dose in ...
STTR Phase II 2023 Department of DefenseDefense Threat Reduction Agency -
Lipid Receptor GPR31 as a Target for Anti-Thrombotic and Stroke Therapy
SBC: OASIS PHARMACEUTICALS, LLC Topic: NHLBIDespite prevalent use of anti-platelet and anti-lipid therapies, stroke remains the third major cause of death and is the leading cause of adult disability in the US with an estimated cost in the range of $34 billion annually. Approximately 20% of the annual 795,000 stroke patients die within one year and 15-30% are permanently disabled. Antiplatelet therapy is mainly used for primary prevention o ...
STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health -
Development of Novel Melanocortin-4 Receptor Peptide Agonists for the Treatment ofMC4R Haploinsufficiency
SBC: COURAGE THERAPEUTICS INC Topic: 102The melanocortin peptide therapeutic setmelanotide, (ImcivreeTM), is highly effective in the treatment of the rare obesity syndromes, POMC and leptin receptor deficiency. However, the drug is ineffective for the most common syndromic obesity, melanocortin-4 receptor (MC4R) deficiency (MC4R haploinsufficiency), found at a prevalence greater than 1/1000 individuals. Further, the drug is ineffective ...
STTR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health -
Using Rendever to improve the quality of life of older adults with cognitive impairments in senior living communities and their family members who live at a distance.
SBC: RENDEVER, INC. Topic: NIAABSTRACTThe United States is experiencing a public health crisis on a massive scale due to the number of people with dementia, lack of cures, and challenges associated with caregiving for this population.1,2 until cures for the dementias are discovered, new technologies and interventions are imperative that can reduce the stress and emotional burden of Alzheimer’s disease (AD) and Alzheimer’s ...
STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health -
Rugged Ultrafast Radiation Hard Scintillators for Nuclear Battlefield
SBC: CAPESYM INC Topic: DTRA20B001This program seeks to develop ultrafast, radiation hard, and rugged scintillators for nuclear battlefields based on high melting-point temperatures oxide crystal. Doping, co-doping, and alloying schemes will be explored to reach the target of < 5ns decay time, light yield >1000 ph/MeV, moderate energy resolution
STTR Phase II 2022 Department of DefenseDefense Threat Reduction Agency