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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Reliable diagnostic differentiation between acute and chronic myocardial infarcts would be of great benefit for cardiac surgeons and interventional cardiologists. Such differentiation could be used to make decisions about which vessels and in what order would be reopened or bypassed. MRI is an intrinsically noninvasive diagnostic tool and the Delayed Enhancemen ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Adenovirus vectored vaccines for Alzheimer's disease

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alzheimer disease (AD) is the most common neurodegenerative disease in the elderly. To date, no satisfactory treatment is available for AD. One of the pathological hallmarks of AD is deposits of amyloid protein (Aa) in neuritic plaques and cerebral vessels. Increasing lines of evidence support the notion that Aa and its precursor (APP) play pathogenetic roles i ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. Advanced, High-Performance, Low-Noise Propeller Designs for Small UxS

    SBC: CFD RESEARCH CORPORATION            Topic: N20AT006

    Improved propeller designs for Small Unmanned Aerial Systems are needed to improve performance and reduce acoustic emissions. Traditional propeller design methods don’t take advantage of advances in coupled fluid, structure and acoustics computational design methods nor advances in high strength, high modulus materials to extend performance of propellers and reduce noise emissions. In the propos ...

    STTR Phase I 2020 Department of DefenseNavy
  6. A Hierarchical and Extendable, Component-Based Simulation Tool for Aircraft Thermal Management Systems

    SBC: CFD RESEARCH CORPORATION            Topic: N19BT025

    The requirements for thermal management on tactical aircraft systems have reached a level at which integrated system design must be considered early in the aircraft design process. An integrated propulsion, power and thermal modeling and simulation design approach is necessary for reduced size, weight and power requirements. At the same time, there is an urgent need for capabilities that enable an ...

    STTR Phase I 2019 Department of DefenseNavy
  7. AI-Driven, Secure Navy Mission Planning via Deep Reinforcement Learning and Attribute-Based Multi-Level Security

    SBC: EH GROUP INC            Topic: N19BT029

    Current mission planning systems allow strike planners and operations centers to perform time-sensitive strike planning, execution monitoring, and validate mission effects using XML-based tools that visualize time critical attack plan and track plan status vs. execution. In this proposed STTR Phase I design for the Next Generation Navy Mission Planning (NGNMPS) system, we will identify expanded op ...

    STTR Phase I 2019 Department of DefenseNavy
  8. Alpha-1 Antitrypsin Gene Therapy for Cystic Fibrosis

    SBC: Generx+, Inc.            Topic: N/A

    DESCRIPTION (Applicant's Abstract): The investigators have developed a plasmid vector that expresses the normal human alpha-1 antitrypsin (AAT) gene in human respiratory epithelium when delivered as a plasmid-cationic liposome complex. In subjects with inherited AAT deficiency, they showed that liposome mediated transfer of the normal AAT gene to the nasal respiratory epi ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  9. Aluminum Metal Matrix Composite UV Mirrors for Small Sats

    SBC: Outpost Technologies, Inc.            Topic: N23AT022

    Outpost Technologies, the CAO, and EO Solutions shall produce UV-class flat optical mirrors meeting the requirements above using proven flight-heritage material, machining, polishing, and coating processes.  Aluminum metal matrix composites (AlMMCs) have unique material properties that provide both mechanically and thermally stable substrates for mirror systems, especially in harsh launch and the ...

    STTR Phase I 2023 Department of DefenseNavy
  10. An Advanced Biosensor for Molecular Interaction Studies

    SBC: MOLECULAR SENSING, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Molecular interactions are central to the understanding of basic biology and cellular function, are paramount to all molecular assays (research and in vitro diagnostics), are essential in biomarker discovery and critical toward evaluating therapeutics. However, the tools available to quantify these interactions have limitations, in so far as they either rely up ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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