Award Data

DESCRIPTION (provided by applicant): Suicide is the 2nd leading cause of death in persons aged 25-34, the 3rd leading cause of death among people in the age groups 10-14 and 15-24, and the 8th leading cause of male deaths. Faith leaders and clergy have been identified in national strategic public health documents as important front-line gatekeepers for suicide prevention. Preliminary research by t ...

This project will produce a method for constructing treatment plans with a guarantee on the quality of the solution. The plans produced by current techniques can fall short of the optimum or needlessly fail to satisfy constraints. As a result, the search for an improved solution is open-ended, exhausting hospital resources and manpower, and providing no assurance to patient or physician that a b ...

DESCRIPTION (provided by applicant): This project will develop a package of planning products for radiation treatment that will introduce a measure of quality assurance now lacking, provide clinicians the opportunity to raise tumor dose, and expose the tradeoffs among the treatment constraints and objectives. The new approach based on mixed integer programming (MIP) will ensure that the dose distr ...

DESCRIPTION (Verbatim from the Applicant's Abstract): The specific aims of this Phase I STTR project, proposed by the American Magnetics, Inc. in partnership with the MIT Francis Bitter Magnet Laboratory, are: 1) experimental demonstration of feasibility of innovative design and operation features applicable to NMR Nb3Sn-magnet/cryocooler systems; and 2) co ...

DESCRIPTION (Provided by Applicant): Work performed during the Phase I of this project has demonstrated that formamide induces selective denaturation of DNA in apoptotic cells. This novel effect of formamide on the stability of apoptotic DNA combined with the detection of denatured DNA with monoclonal antibody (MAb)against single-stranded DNA, has made it possi ...

DESCRIPTION (Provided by Applicant): Work performed during the Phase I of this project has demonstrated that formamide induces selective denaturation of DNA in apoptotic cells. This novel effect of formamide on the stability of apoptotic DNA combined with the detection of denatured DNA with monoclonal antibody (MAb)against single-stranded DNA, has made it possi ...

DESCRIPTION (provided by applicant): Informed consent has become an essential component of the doctor-patient interaction. The informed consent process requires that patients not only be given information about proposed medical treatment, but that it be presented in an understandable way so the patient can make meaningful choices about medical alternatives. At the heart of the inf ...

DESCRIPTION (provided by applicant): Women face a variety of medical decisions during pregnancy and childbirth. While there are extensive educational resources for pregnant women, modern medicine presents decisions that many women are poorly equipped to make. Issues such as prenatal screening and mode of birth after a cesarean delivery require a significant degree of patient education to enable a ...

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DESCRIPTION (provided by the applicant): Autoimmune diseases, such as systemic lupus erythematosus, rheumatoid arthritis, type I diabetes, and multiple sclerosis, are thought to arise from abnormalities of innate or adaptive immune responses. Autoimmune diseases are often difficult to diagnose, as the symptoms can be typical of other conditions and quite vague, such as musculoskeletal complaints ...