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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. AIMSMART: Adaptive, Interactive MDA Semantic Model-based Articulation

    SBC: CYCORP, INC.            Topic: MDA11T003

    We will develop automatic ontology-aligning software, leveraging the enormous existing Cyc AI system to drive the formulation and ranking (pro/con argumentation) of hypotheses about term-term relationships, especially where the relationship is not simple 1-to-1 correspondence. Multiple Cyc micro-theories (contexts) will be created, to hold incommensurate alternative mappings, and logical conseque ...

    STTR Phase II 2013 Department of DefenseMissile Defense Agency
  2. Alafair Biosciences develops cross-linked polysaccharide hydrogel films to addres

    SBC: ALAFAIR BIOSCIENCES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): The goal of this STTR project is to develop a pre-formed, naturally-based hydrogel postoperative adhesion barrier with improved handling characteristics, laparoscopic deliverability, and consistent efficacy. Our technology is based on a novel, patented process that imparts exceptional elasticity and toughness on normally brittle, weak materials. Postoperative a ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. An Advanced Biosensor for Molecular Interaction Studies.

    SBC: MOLECULAR SENSING, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Molecular interactions form the foundation of biology and chemistry. They are central to life itself and determine catalytic activity, cellular function, and therapeutic efficacy. The vast majority of diagnostic procedures depend on some type of specific molecular interaction. Therefore, the ability to perform pure liquid-phase molecular binding analysis at hi ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel Insulin Pathway Agonist for Alzheimer's Disease

    SBC: MEDCHEM PARTNERS LLC            Topic: NIA

    DESCRIPTION (provided by applicant): Even though the association of -amyloid peptide (A ) deposition and Alzheimer's Disease (AD) underpins the major hypothesis for disease progression and possibly causation and several drugs addressing the formation or removal of -amyloid plaques have entered clinical trials, no effective therapy exists to date for AD. This reality calls for new targets th ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. APPSPIRE: expanding the reach of an innovative tobacco control program for youth

    SBC: Radiant Creative Group, LLC            Topic: NIDA

    DESCRIPTION (provided by applicant): Mobile phone technology offers a variety of opportunities for innovative approaches to health communication and intervention. These opportunities have been amplified by the emergence of next-generation smartphone devices that are capable of rich multimedia and sophisticated interactivity. Smartphone-based programs can be integrated seamlessly into a user's ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. A Small Molecule to Activate Tumor Immunity after PLX403 in V600E BRAF Melanoma

    SBC: ARISAPH PHARMACEUTICALS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): In the United States, around 76,250 new cases of melanoma and 9,180 melanoma-related deaths are predicted for 2012. With the therapeutic options currently available, metastatic melanoma patients face the bleak prospectof at best, 10 month's survival and a one-in-ten chance of surviving for 10 years. Surgery and radiation therapy are the mainstay of treatme ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Aspirin-PC for Chemoprevention of Colorectal Cancer

    SBC: PLx Opco Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Colorectal cancer is the third leading cause of cancer-related deaths in the U.S. Based on numerous epidemiological studies and recent prospective trials; the use of daily aspirin is associated with a significant reduction in colorectl cancer incidence, deaths and metastatic spread to other organs. However, the chronic use of this drug is limited due to the sid ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. A Visualization Tool for Computer-Aided Diagnosis of Focal Cortical Dysplasia

    SBC: CORTICOMETRICS LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): This project proposes to build computer-aided diagnostic (CAD) software for use in identifying cortical malformations known as Focal Cortical Dysplasias (FCDs), which are a common cause of epileptic seizures. The intentis for the software, used by a neuroradiologist at a clinical workstation, to decrease the time- intensive nature of the current diagnostic proc ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Carisbamate Treatment for Alcohol Dependence

    SBC: Medication Discovery Texas, Inc            Topic: NIAAA

    DESCRIPTION (provided by applicant): Though not specifically FDA-approved for this indication, topiramate is among the most effective medication treatments for alcohol dependence. Topiramate is rarely used to treat alcohol dependence, however, because it has prominent side effects including somnolence, dizziness, and cognitive disturbances that require gradual dose titration. Many patients stop ta ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Carisbamate Treatment for Alcohol Dependence

    SBC: Medication Discovery Texas, Inc            Topic: NIAAA

    DESCRIPTION (provided by applicant): Though not specifically FDA-approved for this indication, topiramate is among the most effective medication treatments for alcohol dependence. Topiramate is rarely used to treat alcohol dependence, however, because it has prominent side effects including somnolence, dizziness, and cognitive disturbances that require gradual dose titration. Many patients stop ta ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
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