Award Data

This proposal is for the design and development of a challenging, adaptable, and extendible A/I system for use in state-of-the-art computer-based wargames. The development will result in a 3rd generation computer wargame based on modern air power conflictand the ability to apply the technology developed for this project in other wargames ranging from tactical ground-based warfare to naval conflic ...

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The ultimate goal of the proposed project is to develop and implement a robust, high-bandwidth, high-resolution, silicon micromachined piezoresistive floating element shear-stress sensor possessing through-wafer backside electrical contacts for themeasurement of unsteady hypersonic flow phenomena. The measurement of wall shear stress is critical to the understanding of shock-wave/boundary layer ...

DESCRIPTION (provided by applicant): Molecular interactions form the foundation of biology and chemistry. They are central to life itself and determine catalytic activity, cellular function, and therapeutic efficacy. The vast majority of diagnostic procedures depend on some type of specific molecular interaction. Therefore, the ability to perform pure liquid-phase molecular binding analysis at hi ...

Atmospheric pressure non-equilibrium plasma sources are being actively developed for a variety of industrial and military applications. Many of these applications employ ultraviolet (UV) radiation or active species (radicals) generated by the plasma. Theefficiency of plasma sources depends on the energy distribution of electrons which are mainly responsible for the production of radicals and excit ...

Idealized analysis has shown that, for the same propellant supply pressure, higher performance can be obtained in a constant-volume combustion device than the traditional constant pressure rocket. CFDRC proposes an effort consisting of multiple levels ofanalysis, followed by design and testing of a rocket engine prototype that will substantiate this claim. Recent relevant experience in advanced ...

DESCRIPTION (provided by applicant): Research Plan: Somatocor will optimize the preparation of a new class of chirally pure non-peptide somatostatin receptor agonists that have therapeutic advantages over the current generation of marketed somatostatin peptide analog drugs. An enantiospecific synthesis will be developed that enables the manufacture of a clinical drug candidate that meets FDA stand ...

DESCRIPTION (provided by applicant): Controlling mechanical signal transduction to treat osteoarthritis Abstract The TRPV4 calcium (Ca++) permeable ion channel has been shown to be expressed and functional in chondrocytes, the cells responsible for the maintenance of cartilage in weight-bearing joints. Trauma of joints with subsequent damage of cartilage, as well as chronically increased joint loa ...

ABSTRACT: Optical Sciences Corporation (OSC) and the University of Alabama in Huntsville"s Center for Applied Optics (UAH/CAO) will demonstrate the feasibility and present a plan for developing optical instrumentation for the monitoring, mitigation, and removal of cryodeposits accumulated on optical and mechanical surfaces in cryogenic-vacuum radiometric calibration chambers. OSC will investigat ...

Modern processor design is trending increasingly toward multicore architectures. This is problematic for programmers because writing a correct parallel program is known to be difficult compared to writing the equivalent sequential program. Additionally, a wide body of sequential code has already been developed that cannot exploit the power offered by these new cores because it was written in a s ...