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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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AAV2-ASPA-Based Metabolic Intervention for Alzheimer's Disease
SBC: ASKLEPIOS BIOPHARMACEUTICAL, INC. Topic: NIAAbstract We propose to initiate preclinical development of a gene therapeutic targeted to Alzheimer's Disease. The World Health Organization's and Alzheimer's Disease International's report on Dementia (2012) recognizes that the global burden of AlzheimerDisease is forecast to worsen significantly with prevalence predicted to double every 20 years. Interventions that could prov ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Advanced Electroanalytical Methods for Failure Mode Analysis and Screening of Base Metal Capacitors
SBC: MAINSTREAM ENGINEERING CORP Topic: MDA14T003Over 95% of the multilayer ceramic capacitors manufactured worldwide use base metal electrode (BME) technology and they are one of the key components in much of the modern electronics. BME capacitors have, over the last 20 years, made significant improvements in performance and reliability; making them more competitive for a wide range of applications. However, there remains significant concerns ...
STTR Phase I 2015 Department of DefenseMissile Defense Agency -
An Advanced Biosensor for Molecular Interaction Studies.
SBC: MOLECULAR SENSING, INC. Topic: NIGMSDESCRIPTION (provided by applicant): Molecular interactions form the foundation of biology and chemistry. They are central to life itself and determine catalytic activity, cellular function, and therapeutic efficacy. The vast majority of diagnostic procedures depend on some type of specific molecular interaction. Therefore, the ability to perform pure liquid-phase molecular binding analysis at hi ...
STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health -
A Novel, Microscale, Distributable Sensor Technology for Ionizing Radiation
SBC: CFD RESEARCH CORPORATION Topic: DTRA14B004Terrorist use of radioactive nuclear materials via nuclear and/or radiological dispersion devices (dirty bombs) is a serious threat. Therefore, it is critical to detect the proliferation of nuclear material. Critical challenges facing this objective include: (a) high sensitivity detection of signature emissions (e.g., gamma rays) from common radioactive isotopes behind shielding, and (b) cost-effe ...
STTR Phase I 2015 Department of DefenseDefense Threat Reduction Agency -
A novel therapeutic approach for Acute Lung Injury/ARDS
SBC: BIOMARCK PHARMACEUTICALS, LTD Topic: NHLBIDESCRIPTION (provided by applicant): The objective of the proposed project is to advance the development of novel peptides targeting MARCKS (Myristoylated Alanine-Rich C Kinase Substrate) protein as platform drug molecules for the treatment of Acute Lung Injury (ALI) and its more severe form, Acute Respiratory Distress Syndrome (ARDS), thereby providing the first pharmacologic therapeutic for this ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Anti-biofilm agents for the treatment of pulmonary infection in cystic fibrosis p
SBC: AGILE SCIENCES, INC. Topic: NIAIDDESCRIPTION provided by applicant The leading cause of mortality in patients with cystic fibrosis CF is pulmonary failure from lung infections and the predominant organism isolated from these infections is the bacterium Pseudomonas aeruginosa Lung infections of CF patients persist over the lifetime of the patients and are impossible to eradicate due to the ability of bacteria to form biofi ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
A Quantitative Optical Sensor to Monitor Tumor Vascular Physiology
SBC: Zenalux Biomedical, Inc. Topic: 102DESCRIPTION provided by applicant In there were new cases of head and neck cancers HNC in the United States Early detection of new and locally recurrent cancers is clinically important to reduce not only cancer related mortality but also treatment associated morbidity as it impacts multiple organ functions including respiration olfaction hearing eating swallowing and speak ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
Assessing muscle health in older adults with electrical impedance myography
SBC: MYOLEX, INC. Topic: NIADESCRIPTION (provided by applicant): Sarcopenia, or the deterioration of muscle health with advancing age, is a major public health concern in the developed world. Some of the most important factors underlying the development of sarcopenia are age- relatedchange in muscle composition, including the replacement of muscle fibers by fat and the loss of muscle force production. Declines in muscle comp ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Contraceptive testing for semen availability in male monkeys
SBC: EPPIN PHARMA INC Topic: NICHDDESCRIPTION provided by applicant The global contraceptives market was valued at $ billion in and is expected to grow at a CAGR of from to to reach an estimated value of $ billion in An important high impact driver of this market is the prevalence of unintended pregnancies In the US there are million unintended pregnancies annually through inconsistent or ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Controlling mechanical signal transduction to treat osteoarthritis
SBC: Cytex Therapeutics, Inc. Topic: NIADESCRIPTION (provided by applicant): Controlling mechanical signal transduction to treat osteoarthritis Abstract The TRPV4 calcium (Ca++) permeable ion channel has been shown to be expressed and functional in chondrocytes, the cells responsible for the maintenance of cartilage in weight-bearing joints. Trauma of joints with subsequent damage of cartilage, as well as chronically increased joint loa ...
STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health