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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  2. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Reliable diagnostic differentiation between acute and chronic myocardial infarcts would be of great benefit for cardiac surgeons and interventional cardiologists. Such differentiation could be used to make decisions about which vessels and in what order would be reopened or bypassed. MRI is an intrinsically noninvasive diagnostic tool and the Delayed Enhancemen ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  4. Adenovirus vectored vaccines for Alzheimer's disease

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Alzheimer disease (AD) is the most common neurodegenerative disease in the elderly. To date, no satisfactory treatment is available for AD. One of the pathological hallmarks of AD is deposits of amyloid protein (Aa) in neuritic plaques and cerebral vessels. Increasing lines of evidence support the notion that Aa and its precursor (APP) play pathogenetic roles i ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. A device containing an immobilized chelator to remove aluminum from total parente

    SBC: ALKYMOS, INC            Topic: NICHD

    DESCRIPTION (provided by applicant): A high percentage of the ~ 500,000 children born prematurely each year in the US require intravenous feeding after birth because they do not tolerate oral feeding. This is accomplished with a total parenteral nutrition (TPN) solution, which is prepared from component solutions: small and large volume parenterals (SVPs and LVPs). Aluminum (Al) is a common contam ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  6. A device containing immobilized chelator to remove aluminum from TPN solutions

    SBC: ALKYMOS, INC            Topic: N/A

    DESCRIPTION (provided by applicant): A high percentage of the ~ 470,000 children born prematurely each year in the US require intravenous feeding after birth because they do not tolerate oral feeding. This is accomplished with a total parenteral nutrition (TPN) solution, which is prepared from component solutions: small and large volume parenterals (SVPs and LVPs). Aluminum (Al) is a common conta ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Advanced Data Association Algorithms to Address Emerging Threats

    SBC: Archarithms, Inc            Topic: MDA19T001

    The proposed approach provides innovative sensor data association algorithms capable of performing correct data association in multi-target tracking environments with one or more sensors. Current air and missile threats have the ability to fly non-ballistic, highly maneuvering hypersonic trajectories, and the ability to maintain closely spaced trajectories. Improved detection/track association is ...

    STTR Phase I 2020 Department of DefenseMissile Defense Agency
  8. Advanced Hit Detection Systems

    SBC: FREENT TECHNOLOGIES, INC.            Topic: MDA13015

    FreEnt Technologies, Inc. (FreEnt) and Johns Hopkins Universitys Applied Physics Laboratory (APL) are proposing a multiple-hit detection sensor called the Optical Lethality Measurement System (OLMS). This system is based on the Planar Optical Penetration Sensor (POPS) technology (originally developed and patented by APL) and prior art associated with the Blast Initiation Detector (BID). The BID is ...

    STTR Phase II 2017 Department of DefenseMissile Defense Agency
  9. Advanced Interceptor Infra-Red Search and Track System (IRSTS) for Missile Defense Applications

    SBC: Oceanit Laboratories, Inc.            Topic: MDA08T002

    The Oceanit¡¦s/APL Foveal InfraRed Search and Track (FIRST) prototype is a dual channel cryogenic WFOV optical sensor system. FIRST provides multifaceted support for an airborne IR search and track and uses the unique Multi-target-tracking Optical Sensor-array Technology (MOST) sensor chip, which has been developed at MDA. FIRST supports instantaneous field-of-view up to 90 degrees, with 360 deg ...

    STTR Phase II 2010 Department of DefenseMissile Defense Agency
  10. Advanced Interceptor Infra-Red Search and Track System (IRSTS) for Missile Defense Applications

    SBC: Oceanit Laboratories, Inc.            Topic: MDA08T002

    The Oceanit / John’s Hopkins, Applied Physics Laboratory (Oceanit / APL) team proposes a Foveal IRSTS (FIRST system) that can provide extremely accurate tracking information as well as providing discrimination and kill assessment metrics. Custom algorithms and processing methods will take advantage of a custom dual-format architecture to address and develop new optical processing methods and cap ...

    STTR Phase I 2009 Department of DefenseMissile Defense Agency
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