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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A biochemical companion diagnostic platform to measure kinase inhibitor pharmacodynamics in leukemia

    SBC: MICROFLUIDIC INNOVATIONS, LLC            Topic: 102

    DESCRIPTION provided by applicant Kinase inhibitors created a new paradigm in chemotherapy and are a major focus of new oncology drug development The Bcr Abl inhibitor imatinib was a breakthrough drug for chronic myelogenous leukemia with overwhelming early results however at least of patients are either intolerant resistant or experience recurrence within years and individual respo ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. A computational and Experimental Investigation of Transient Nonlinear Viscous Aeroelastic Effects

    SBC: CFD Research Corporation            Topic: N/A

    N/A

    STTR Phase I 1999 Department of DefenseAir Force
  3. A Computational Framework for Multiscale Simulations of Weakly Ionized Plasmas

    SBC: CFD Research Corporation            Topic: AF07T022

    The goal of the proposed research is to develop a unified computational framework integrating adequate physical models for simulating complex non-equilibrium plasmas. Plasma dynamics is characterized by disparate spatial and temporal scales each described by appropriate physical models. The project aims to classify possible scenarios and develop general recipes for clustering phase space to dynami ...

    STTR Phase I 2007 Department of DefenseAir Force
  4. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Adaptive Artificial Intelligence for Next-Generation Conflict Simulation

    SBC: John Tiller Software, Inc            Topic: N/A

    This proposal is for the design and development of a challenging, adaptable, and extendible A/I system for use in state-of-the-art computer-based wargames. The development will result in a 3rd generation computer wargame based on modern air power conflictand the ability to apply the technology developed for this project in other wargames ranging from tactical ground-based warfare to naval conflic ...

    STTR Phase I 2003 Department of DefenseAir Force
  6. Adaptive Artificial Intelligence for Next-Generation Conflict Simulation

    SBC: John Tiller Software, Inc            Topic: AF03T022

    This proposal is for the design and development of a challenging, adaptable, and extendible AI system for use in state-of-the-art computer-based wargames. The development will result in a 3rd generation computer wargame based on modern air power conflict and the ability to apply the technology developed for this project in other wargames ranging from tactical ground-based warfare to naval conflic ...

    STTR Phase II 2004 Department of DefenseAir Force
  7. Adaptive Integrated Multi-Modal Sensing Array

    SBC: Polaris Sensor Technologies, Inc.            Topic: AF08BT02

    Nanoscale infrared detectors are emerging as a potentially powerful alternative to traditional infrared detector technologies. The University of New Mexico has developed dots in a double well (DDWELL) quantum dot infrared photodetectors which have a spectral responsivity that can be tuned by controlling the bias voltage applied. In this Phase II effort, Polaris Sensor and UNM would fabricate a g ...

    STTR Phase II 2010 Department of DefenseAir Force
  8. Adaptive Integrated Multi-Modal Sensing Array

    SBC: Polaris Sensor Technologies, Inc.            Topic: AF08BT02

    Polaris Sensor Technologies is proposing to use quantum dot technology that has been  recently developed which has the ability to tune the spectral response of a sensor in real-time.   In the Phase I we will study the feasibility of integrating such a focal plane to either fixed or adaptive polarization capability.  The adaptive polarization capability would be based on dynamically controllabl ...

    STTR Phase I 2009 Department of DefenseAir Force
  9. Adiabatic Circuits for Ultra-Low Energy Consumption

    SBC: INDIANA INTEGRATED CIRCUITS LLC            Topic: AF18BT013

    Adiabatic reversible logic provides a way to dramatically reduce power dissipation by recovering the energy used to encode information, rather than dissipating the energy to heat, as is done in conventional CMOS. For Phase I we will design test circuits that will evaluate the energy savings in adiabatic reversible logic, as compared to conventional logic. In addition to these smaller circuits, a M ...

    STTR Phase I 2019 Department of DefenseAir Force
  10. Advanced Combat Simulation for More Effective Anti-Terrorist Operations

    SBC: John Tiller Software, Inc            Topic: AF07T023

    This proposal is for the development of an architecture for asymmetric and anti-terrorist simulations and the application of that architecture in the design and development of multiple user-friendly, PC-based, artificially intelligent asymmetric combat simulation systems. This effort will utilize a number of existing, mature computer wargames and will focus on enhancements to those game systems u ...

    STTR Phase I 2007 Department of DefenseAir Force
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