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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A biochemical companion diagnostic platform to measure kinase inhibitor pharmacodynamics in leukemia

    SBC: MICROFLUIDIC INNOVATIONS, LLC            Topic: 102

    DESCRIPTION provided by applicant Kinase inhibitors created a new paradigm in chemotherapy and are a major focus of new oncology drug development The Bcr Abl inhibitor imatinib was a breakthrough drug for chronic myelogenous leukemia with overwhelming early results however at least of patients are either intolerant resistant or experience recurrence within years and individual respo ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Acceleration of Commercial Low-Rank Matrix Solver via SLATE

    SBC: IERUS TECHNOLOGIES, INC            Topic: 07a

    Performing accurate simulations of large- and multi-scale electromagnetics problems has far-reaching implications The same physics governs applications as diverse as rare earth content reduction in DC motor design; wireless propagation in dense urban environments and novel antenna design, both key issues in the pending 5G communications boom; electromagnetic sounding for subsurface exo-terrestrial ...

    STTR Phase I 2020 Department of Energy
  3. A Contaminant Tolerant Solvent for Carbon Capture in Existing Coal-Fired Power Plants

    SBC: Green Technology Ltd Co.            Topic: 23a

    This Small Business Innovation Research Phase I project will study the feasibility of a novel contaminant-tolerant solvent/stripping chemical hybrid process for post-combustion CO2 capture from utility flue gas. The process will use a proprietary solvent technology to achieve DOEs goal of 90% or greater CO2 emissions reduction at existing coal-fired power plants with no more than a 30% increase in ...

    STTR Phase I 2011 Department of Energy
  4. A Contaminant Tolerant Solvent for Carbon Capture in Existing Coal-Fired Power Plants

    SBC: Green Technology Ltd Co.            Topic: 23a

    In the context of post-combustion CO2 capture processes, solvents with fast CO2 absorption rates will require more energy for regeneration. This challenge is exacerbated when aqueous solvents are applied to the capture of post-combustion CO2 from a utility gas stream, which contains such unique characteristics as high volumetric flow rate, low CO2 vapor pressure, and the presence of gas contaminan ...

    STTR Phase II 2012 Department of Energy
  5. A Continuous Low-Inventory Tritium Fuel Cycle for Fusion

    SBC: Cryogenic Applications F, Inc.            Topic: N/A

    A Continuous Low-Inventory Tritium Fuel Cycle for Fusion DOE Grant No. DE-FG02-98ER86075 Amount: $99,999 Small Business Cryogenic Applications F, Inc. 450 Bacon Springs Lane Clinton, TN 37716-5311 Dr. Christopher A. Foster, Principal Investigator Dr. Christopher A. Foster, Business Official (423) 435-5433 Research Institution Los Alamos National Laboratory MS C334 P.O. Box 1663 Los Alamos, NM ...

    STTR Phase I 1998 Department of Energy
  6. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  7. Algorithm to Identify Patients at Risk of Medication-Related Hospitalization

    SBC: L. KRENK, INC.            Topic: R

    The long range goal of this fast track research application is to improve healthcare quality and reduce healthcare costs nationwide among those at risk for medication related hospitalizationThe specific objective of this proposed research is to develop an algorithm that uses existing electronic health information to efficiently identify patients at risk of medication related hospitalization so tha ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. A Mesh Free Framework for Mechanical Simulations of Microstructure Data Files

    SBC: CFD Research Corporation            Topic: 07a

    The Exascale Computing Project is tasked to develop the next generation of high performance computing systems capable of computing at 50 to 100 times faster than current HPC systems. Computing at this extreme-scale will significantly enhance the value of materials modeling and simulation to basic materials research and engineering In particular, computing at the extreme scale will enable a higher ...

    STTR Phase I 2019 Department of Energy
  9. A Multi-physics Analysis Capability for Engine Materials

    SBC: Sunergolab Inc.            Topic: 03b

    Computer-aided Engineering software that apply the Finite Element Method to perform a multi-physics analysis have received widespread acceptance for traditional macro-scale material systems. Challenges persist in the modeling of complex coupled processes in environmental/thermal barrier coatings (E/TBCs) used to protect substrate material against the corrosive environment in the hot section parts ...

    STTR Phase I 2019 Department of Energy
  10. A new generation of targeted therapeutics for the treatment of cancer

    SBC: NERX BIOSCIENCES, INC.            Topic: NCI

    DESCRIPTION provided by applicant Development of novel lung cancer therapeutics targeting the DNA damage response Abstract Lung tissue is constantly exposed to a wide variety of inhaled chemical agents While the majority of these maybe innocuous those that damage DNA have severe consequences Thus the DNA damage response DDR and DNA repair in these tissues is extremely important The vast ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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