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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A biochemical companion diagnostic platform to measure kinase inhibitor pharmacodynamics in leukemia

    SBC: MICROFLUIDIC INNOVATIONS, LLC            Topic: 102

    DESCRIPTION provided by applicant Kinase inhibitors created a new paradigm in chemotherapy and are a major focus of new oncology drug development The Bcr Abl inhibitor imatinib was a breakthrough drug for chronic myelogenous leukemia with overwhelming early results however at least of patients are either intolerant resistant or experience recurrence within years and individual respo ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Accelerated preconditioned RANS simulations for Hypersonic Flight Vehicles

    SBC: RESEARCH IN FLIGHT LLC            Topic: AFX23DTCSO1

    Research in Flight and Utah State University are proposing the development of an accelerated preconditioner for high-fidelity numerical simulations of hypersonic air vehicles in early design stages. This capability will assist hypersonic aircraft OEM to o

    STTR Phase I 2023 Department of DefenseAir Force
  3. Accurate Protein Identification using Peptide Separation Information and Tandem M

    SBC: PREDICTIVE PHYSIOLOGY AND MEDICINE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A significant problem currently hindering proteomics studies is the identification of peptides and proteins from mass spectral data. This problem is manifest in the difficulty to establish confidence limits of protein a nd peptide identifications. A serious concern is the tendency for the occurrence of false positive assignments. The development of an integrate ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin

    SBC: VAXIN INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  5. A computational and Experimental Investigation of Transient Nonlinear Viscous Aeroelastic Effects

    SBC: CFD RESEARCH CORPORATION            Topic: N/A

    N/A

    STTR Phase I 1999 Department of DefenseAir Force
  6. A Computational Framework for Multiscale Simulations of Weakly Ionized Plasmas

    SBC: CFD RESEARCH CORPORATION            Topic: AF07T022

    The goal of the proposed research is to develop a unified computational framework integrating adequate physical models for simulating complex non-equilibrium plasmas. Plasma dynamics is characterized by disparate spatial and temporal scales each described by appropriate physical models. The project aims to classify possible scenarios and develop general recipes for clustering phase space to dynami ...

    STTR Phase I 2007 Department of DefenseAir Force
  7. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Reliable diagnostic differentiation between acute and chronic myocardial infarcts would be of great benefit for cardiac surgeons and interventional cardiologists. Such differentiation could be used to make decisions about which vessels and in what order would be reopened or bypassed. MRI is an intrinsically noninvasive diagnostic tool and the Delayed Enhancemen ...

    STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Adaptable Cyber Defense for Autonomous Air Operations

    SBC: OCEANIT LABORATORIES INC            Topic: AF19CT003

    In this Phase I SBIR, Oceanit will develop a novel, powerful, adaptable cyber defense capability to support autonomous Air Force weapons systems.

    STTR Phase I 2020 Department of DefenseAir Force
  10. Adaptive Artificial Intelligence for Next-Generation Conflict Simulation

    SBC: John Tiller Software, Inc            Topic: N/A

    This proposal is for the design and development of a challenging, adaptable, and extendible A/I system for use in state-of-the-art computer-based wargames. The development will result in a 3rd generation computer wargame based on modern air power conflictand the ability to apply the technology developed for this project in other wargames ranging from tactical ground-based warfare to naval conflic ...

    STTR Phase I 2003 Department of DefenseAir Force
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