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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. A biochemical companion diagnostic platform to measure kinase inhibitor pharmacodynamics in leukemia

    SBC: MICROFLUIDIC INNOVATIONS, LLC            Topic: 102

    DESCRIPTION provided by applicant Kinase inhibitors created a new paradigm in chemotherapy and are a major focus of new oncology drug development The Bcr Abl inhibitor imatinib was a breakthrough drug for chronic myelogenous leukemia with overwhelming early results however at least of patients are either intolerant resistant or experience recurrence within years and individual respo ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Acute-infarct selective cardiac MRI contrast agent

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this project is to demonstrate the ability of our acute myocardial infarct selective paramagnetic contrast agent Gadolinium ABE DTTA to differentiate between acute and chronic infarcts in a reliable manner using contrast enhanced magnetic resonance imaging ceMRI In our Phase I data we have shown that Gd ABE DTTA exclusively highlight ...

    STTR Phase II 2010 Department of Health and Human ServicesNational Institutes of Health
  3. Advanced Materials for the Design of Lightweight JP5/JP8/DS2 Fueled Engines for UAVs

    SBC: ENGINE RESEARCH ASSOCIATES INC            Topic: N10AT001

    Develop a high power to weight, compact, heavy fuel MCC engine using advanced high strength materials. This new MCC engine design will also offer high durability and high efficiency with an extremely low acoustic and IR signature for use in future small UAVs. The overall objective of this Phase I development program is to develop a JP-5, JP-8 or DS2 MCC engine using advanced high strength to weigh ...

    STTR Phase I 2010 Department of DefenseNavy
  4. Affordable Unmanned Underwater Vehicle (UUV) Power System Architecture

    SBC: PC Krause And Associates, Inc.            Topic: N09T015

    The primary objective of the proposed work is to develop an unmanned underwater vehicle (UUV) power system architecture that is simultaneously scalable to multiple UUV sizes, light weight, affordable, and adaptable. This will be accomplished through the development of “smart” power units (SPU’s) that can be readily interconnected to provide distributed and coordinated power management for t ...

    STTR Phase I 2009 Department of DefenseNavy
  5. A Hierarchical and Extendable, Component-Based Simulation Tool for Aircraft Thermal Management Systems

    SBC: CFD Research Corporation            Topic: N19BT025

    The requirements for thermal management on tactical aircraft systems have reached a level at which integrated system design must be considered early in the aircraft design process. An integrated propulsion, power and thermal modeling and simulation design approach is necessary for reduced size, weight and power requirements. At the same time, there is an urgent need for capabilities that enable an ...

    STTR Phase I 2019 Department of DefenseNavy
  6. AI-Driven, Secure Navy Mission Planning via Deep Reinforcement Learning and Attribute-Based Multi-Level Security

    SBC: EH GROUP            Topic: N19BT029

    Current mission planning systems allow strike planners and operations centers to perform time-sensitive strike planning, execution monitoring, and validate mission effects using XML-based tools that visualize time critical attack plan and track plan status vs. execution. In this proposed STTR Phase I design for the Next Generation Navy Mission Planning (NGNMPS) system, we will identify expanded op ...

    STTR Phase I 2019 Department of DefenseNavy
  7. Air Cycle Machine Low Friction, Medium Temperature, Foil Bearing Coating

    SBC: IBC Materials & Technologies, LLC            Topic: N16AT005

    In this proposed SBIR program, IBC Materials & Technologies, in conjunction with our industry partner Mechanical Solutions, Inc. (MSI) and Texas A&M University, will leverage our knowledge and experience in the domain of industrial metallic coatings to develop a metallurgical coating solution for the Air Foil Bearing. IBC has deep expertise in a variety of industrial coating processes including mu ...

    STTR Phase I 2016 Department of DefenseNavy
  8. Algorithm to Identify Patients at Risk of Medication-Related Hospitalization

    SBC: L. KRENK, INC.            Topic: R

    The long range goal of this fast track research application is to improve healthcare quality and reduce healthcare costs nationwide among those at risk for medication related hospitalizationThe specific objective of this proposed research is to develop an algorithm that uses existing electronic health information to efficiently identify patients at risk of medication related hospitalization so tha ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Analysis & Adaptation of Advanced Fischer Tropsch Catalyst Structures and Resulting BOP Reductions to Fulfill Future Navy Fuel Needs

    SBC: INTRAMICRON INC            Topic: N07T027

    Microfibrous Entrapped Catalysts (MFEC) are proposed for detailed analysis to determine their potential to meet future Navy fuel needs by means of highly selective Fischer Tropsch Synthesis (FTS). MFEC are comprised of small grains of supported catalysts (ca. 10-200 micron diameter) entrapped within sinter-locked networks of micron diameter metal fibers. Metal fibers comprise only 5-10 vol% of the ...

    STTR Phase I 2008 Department of DefenseNavy
  10. Analysis & Adaptation of Advanced Fischer Tropsch Catalyst Structures and Resulting BOP Reductions to Fulfill Future Navy Fuel Needs

    SBC: INTRAMICRON INC            Topic: N07T027

    In the Phase I study, IntraMicron found that Microfibrous Entrapped Catalysts (MFEC) increased effective thermal conductivity by 3~12 times, improved selectivity and product yield, and significantly reduced the Balance of Plant (BOP) compared with packed beds; Ceramatec prepared novel catalysts for highly selective jet fuel production and designed a FTS modular reactor with fast external heat tran ...

    STTR Phase II 2009 Department of DefenseNavy
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