Award Data

GTL has been developing three transformational technologies that have the capability to disrupt the traditional launch vehicle paradigm. BHL composite cryotank technology provides a four times improvement over large Al-Li tanks, offering a 6 percentage point improvement in stage PMF. Superior Stability Engine is an innovative liquid rocket engine configured to maximize combustion stability margi ...

DESCRIPTION (provided by applicant): Current approaches to medical education produce new physicians with insufficient clinical competency to practice effectively with limited supervision, which has serious implications for patient outcomes during hospitaloff hours. Up to 70% of patients admitted to a hospital are admitted on nights or weekends, when staffing is low and residents may be in charge o ...

DESCRIPTION provided by applicant We have shown that immunization of rabbits with multiple antigenic peptides MAPs displaying sequence from domain of protective antigen PA elicit antibodies specific for a linear determinant within the loop of PA that mediate potent neutralization of lethal toxin LeTx in vitro We have now shown in two separate large studies that antibodies aga ...

DESCRIPTION (provided by applicant): Target enrichment for next-generation sequencing enables researchers to reduce the burden of sequence data analysis, obtain higher levels of statistical significance by examining more genomes and increase sequencing coverage depth. The goal of this STTR proposal is to develop and commercialize a novel technology capable of amplification-free megabase target seq ...

HJ Science & Technology proposes a programmable, low-cost, and compact microfluidic platform capable of running automated end-to-end processes and optimization of cellular engineering and synthetic biology applications. In collaboration with Lawrence Berkeley National Laboratory and the Joint Genome Institute, we will establish the feasibility of the proposed microfluidic automation technology by ...

As a result of significant technical effort, the Phase I was successful in delivering a solar simulator prototype that not only proved the initial concept but will significantly reduce future risk and increase our ability to deliver a fully-functional solar simulator in Phase II. The proposed innovation is an LED-based, laboratory-scale, solar simulator. The proposed innovation simulates AM0 re ...

DESCRIPTION provided by applicant In Phase our team was able to enhance the ABM B Alert system for use in on the road evaluations by reducing the overall profile of the hardware system introducing real time commenting for marking events in real world activities and assessing and confirming current artifact rejection algorithms for sufficiency in real world environments In addition the ...

DESCRIPTION provided by applicant Antibody therapy for serious bacterial infections using polyclonal immune antitoxin or anti capsule horse serum actually predates small molecule antibiotic use However for reasons of safety convenient empirical use and cost the development of broader spectrum antibiotics rapidly supplanted the use of immune serum But drug resistance is quickly reducing th ...

DESCRIPTION provided by applicant Metastasis or dissemination of primary tumor cells is the major cause of mortality in cancer patients Circulating tumor cells CTCs in the bloodstream are key players in the establishment of metastatic tumors Recent studies demonstrated that the number of CTCs present in patient blood directly correlate with cancer progression recurrence and survival rate ...

Strain sensor information is used in nature to achieve robust flight, good rejection of wind disturbances, and stable head motion. Similar man-made sensing devices will be used to demonstrate flight control using Fly-by-Feel, with the overall objective of achieving similarly good performance with piloted and autonomous vehicles. The Phase I work demonstrated the feasibility of using strain sensor ...