Award Data

ABSTRACT: The overall goal of the proposed effort is to develop and demonstrate a general-purpose, fast, and reliable management and learning software tool for analyzing massive data sets generated by dynamic multi-disciplinary simulation. In Phase I, key technology elements were developed and proof-of-principle was successfully demonstrated. Data management software encapsulating salient feature ...

? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...

DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

DESCRIPTION provided by applicant Metastasis or dissemination of primary tumor cells is the major cause of mortality in cancer patients Circulating tumor cells CTCs in the bloodstream are key players in the establishment of metastatic tumors Recent studies demonstrated that the number of CTCs present in patient blood directly correlate with cancer progression recurrence and survival rate ...

DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

The project will remove a key difficulty that currently hampers many existing methods for computing unsteady electromagnetic waves on unbounded regions. Numerical accuracy and/or stability may deteriorate over long times due to the treatment of artificial outer boundaries. We propose to develop a universal algorithm and software that will correct this problem by employing the Huygens' principle an ...

Tier1 Performance Solutions proposes to develop CSAT (Common Situation Awareness Tool), a solution that supports more effective event integration and task management, in order to improve situation awareness and knowledge sharing for missile defense system users and stakeholders. At the core of the CSAT solution is an active knowledge management platform designed so that all users share a common sc ...

ABSTRACT: The goal of this project is to develop theoretical models for electrode erosion in high-pressure arcs and incorporate them into computational tools for simulations of arc heaters. The complexity of the electrode material removal process is associated with the multi-phase nature of the arc-electrode interactions, melting and vaporization of the electrodes near the arc foot. Available mod ...

This STTR Phase I proposal proposes to design and develop reactive filter media using nanofiber technology to capture corrosion inducing particulate matter present in coastal region air. The fibrous filter media will be functionalized using ion exchange chemistry which is known to react with salt ions. The media will be characterized for its filtration performance, resistance to airflow, and dus ...

ABSTRACT: Due to scarcity of spectrum, Dynamic Spectrum Access (DSA) becomes a needed technology to improve the utilization of electromagnetic spectrum for DoD satellite communication. However, current DSA approaches are developed for terrestrial communications without addressing the unique challenges for SATCOM environments such as error-prone spectrum sensing, high mobility, and large coverage. ...