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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A chimeric protein for the selective expansion of regulatory T cells

    SBC: SAHANE BIOTECH INC            Topic: NIAID

    DESCRIPTION provided by applicant Type diabetes T D is a chronic disease caused by the autoimmune destruction of the insulin producing beta cells in the pancreas Current treatment options for T D are severely limited All patients diagnosed with T DM are placed on life long insulin therapy and the current standard of care for adult patients with T DM is intensive diabetes therapy to avoid ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Adiponectin Secretion Enhancer Synthetic Organic Drug Discovery and Development

    SBC: DISCOVERYBIOMED, INC.            Topic: 200

    DESCRIPTION provided by applicant DiscoveryBioMed Inc DBM completed recently Phase I SBIR funded goals milestones specific experimental aims and efforts to screen synthetic organic small molecules on immortalized and primary differentiated human adipocyte platforms and to validate the high throughput screening HTS based Drug Discovery output with a Critical Path of bioassays dete ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. A Force-controlled Probe Based Platform for Single-Cell Biomolecular Delivery

    SBC: INFINITESIMAL, LLC            Topic: 100

    DESCRIPTION provided by applicant This proposed Phase II project will lead to a commercial product capable of transfecting individual target cells This new biotool uses a patented microfabricated chip called a nanofountain probe NFP to deliver molecules into live individual target cells by single cell electroporation which induces temporary nanopores in the cell membrane via the applicat ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. A Holographic Waveguide Display Based Low Vision Eyewear

    SBC: BIOLIGHT ENGINEERING LLC            Topic: N

    DESCRIPTION provided by applicant Low vision rehabilitation is the only proven way to restore functional vision and maintain a high quality of life in patients with permanent vision impairment Low vision aids are devices that manipulate visual information for example magnify images to compensate for impaired vision The patientandapos s willingness to accept a low vision aid ability to ada ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. A mechanism based computational tool to optimize pulmonary drug delivery

    SBC: CFD RESEARCH CORPORATION            Topic: 300

    DESCRIPTION provided by applicant Pulmonary drug delivery has emerged as a noninvasive alternative route for the treatment of lung diseases asthma COPD CF and lung cancer In order to obtain the desired level of effectiveness and safety of the inhaled drugs an appropriate deposition on the targeted region and subsequent absorption in the targeted region is vital Multiscale multidisciplin ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Aminomethyl benzamides as novel anti Ebola agents

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    Ebola EBOV and Marburg MARV viruses belong to the family Filoviridae and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction with an incubation period of days Because of the safety concerns these viruses are designated as the biosafety level agents Currently there is no effective vaccine or therapeutic treatment against filoviral infection and pathogenes ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Aminopiperidines as novel anti influenza agents

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    Influenza A viruses belong to the orthomyxoviridae family with a negative sense segmented RNA genome which can cause seasonal or pandemic flu with high morbidity and significant mortality Vaccination is the most prevalent prophylactic means for controlling influenza infections However an effective vaccine usually takes at least months to develop for the circulating strains Furthermore vac ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. A mobile app to reduce treatment-related financial burden for cancer patients

    SBC: Vivor, Llc            Topic: NCI

    There is a fundamental knowledge gap in how to immediately reduce cancer patientsandapos treatment related financial burden Cancer patients pay more out of pocket for their care than those with other chronic illnesses Half of all elderly cancer patients have high treatment related out of pocket financial burden This financial burden has well defined harmful effects even among insured cancer pa ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. A new biomarker for diabetic foot ulcers

    SBC: Noveratech L.L.C.            Topic: 100

    DESCRIPTION provided by applicant This proposal is submitted in response to the new NIDDK announcement PA calling for development of methodologies or biomarkers to help understand the pathophysiology of T D type diabetes T D complications An estimated of the million diabetic patients in this country will develop diabetic foot ulcers DFU at some point in their lives ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  10. A new technique for diabetic foot ulcers

    SBC: Noveratech L.L.C.            Topic: 200

    DESCRIPTION provided by applicant This proposal is submitted in response to the new NIDDK announcement PA calling for development of new diagnostic monitoring and therapeutics technologies for the complications of type diabetes T D An estimated of the million diabetic patients in this country will develop diabetic foot ulcers DFU at some point in their lives Curr ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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