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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A mechanism based computational tool to optimize pulmonary drug delivery

    SBC: CFD RESEARCH CORPORATION            Topic: 300

    DESCRIPTION provided by applicant Pulmonary drug delivery has emerged as a noninvasive alternative route for the treatment of lung diseases asthma COPD CF and lung cancer In order to obtain the desired level of effectiveness and safety of the inhaled drugs an appropriate deposition on the targeted region and subsequent absorption in the targeted region is vital Multiscale multidisciplin ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. A method for accurate and sensitive detection of HIV drug-resistant minority variants

    SBC: Medosome Biotec, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Drug resistance to HIV is a major threat to achieving long term viral suppression in HIV individuals Up to of newly infected individuals acquire HIV with resistance to at least one of the major antiretroviral classes and incomplete viral suppression and virologic failure are often associated with drug resistance Therefore current DHHS guideline recomme ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. A New Technique for Diabetic Foot Ulcers

    SBC: Noveratech L.L.C.            Topic: 200

    ABSTRACT Diabetes is the leading cause of nontraumatic lower extremity amputations in the United States Diabetic foot ulcers DFUs are responsible for more hospitalizations than any other diabetic complications Currently even the best available treatments achieve only a healing rate for these wounds and this healing is often only temporary with a chance of recurring Our company has ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. A Next Generation, Low Cost Tracking System for Healthcare

    SBC: Q-Track Corporation            Topic: 600

    DESCRIPTION provided by applicant The goal of the Phase I study is to determine the feasibility of piloting a low cost Real Time Location System RTLS for use in healthcare based on a novel technology known as Near Field Electromagnetic The proposed QHealth system promises to support a number of healthcare applications such as equipment management workflow optimization hand hygiene complian ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. An Innovative Device Integrating Cryopreservation, Storage, and Artificial Insemination of Mouse Sperm

    SBC: PARATECHS CORP            Topic: 100

    DESCRIPTION provided by applicant ParaTechs Corporation aims to provide researchers with advanced technology and methods to simplify procedures for laboratory animal models While actively supporting efforts to `reduce replace and refineandapos animal use ParaTechs provides safe and efficient alternatives for surgical procedures We have already brought to market a nonsurgical embryo transfe ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. A Novel Lipotherapy to Reduce Infarct Size Following Myocardial Infarction

    SBC: ENDOPROTECH, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant According to the CDC in ischemic heart disease is the leading cause of death worldwide and in the US approximately patients died of ischemic heart disease It is well established in clinical practice that recanalization of he infarct related artery IRA using percutaneous coronary intervention PCI enhances myocardial salvage and outcomes in pa ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel STAT3 Inhibitor Targeting its DNA-Binding Site for Drug Development

    SBC: QRKANSWER LLC            Topic: NCI

    DESCRIPTION provided by applicant Cancer is a major public health problem and a leading cause of mortality claiming more than half million lives every year in the US While major progresses have been made in developing targeted anticancer therapeutics many cancers such as lung cancers have no effective treatments Unfortunately many ideal oncogenic targets including transcription factors for ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. A Predictive In Vitro Model for Screening Personalized Responses to CFTR-directed Therapeutics

    SBC: CFD RESEARCH CORPORATION            Topic: NHLBI

    Abstract The objective of this study is to develop a novel predictive in vitro model for personalized responses to CFTR directed therapeutics This proposal responds to RFA HL Human Cellular Models for Predicting Individual Responses to Cystic Fibrosis Transmembrane Conductance Regulator Directed Therapeutics Cystic fibrosis CF is a life shortening genetic disease caused by loss of ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. A simple and effective diagnostic test for gastrointestinal bleeding to improve patient outcomes

    SBC: CUMBERLAND PHARMACEUTICALS, INC.            Topic: 300

    DESCRIPTION provided by applicant Problem Lower gastrointestinal bleeding is a significant medical problem in the United States accounting for more than hospital admissions and tens of billions of dollars of healthcare spending annually It is common for bleeding from a single site to stop and restart multiple times The three modalities now used to diagnose and locate gastrointestina ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Chemical enhancement of CRISPR/Cas9 mediated site-specific genome engineering

    SBC: NERX BIOSCIENCES, INC.            Topic: 200

    DESCRIPTION provided by applicant Chemical enhancement of CRISPR Cas mediated site specific genome engineering Abstract Programmable nucleases including Zinc Finger Nucleases TALENs meganucleases and the CRISPR Cas system allow for site specific genome engineering The ability to make targeted genetic modifications has opened up a wide variety of options for scientists in industry and aca ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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