Award Data

Aflatoxins are a paradigm among fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk forthe development of hepatocellular carcinoma. Currently, there are no known countermeasures that can selectively mitigate aflatoxin toxicity andthe available options are only symptomatic treatments. To meet this challenge, we propose to harness the microbio ...

DESCRIPTION provided by applicant Therapeutics is focused on the development of adjuvant systems with desired immune activities for targeted indications The Companyandapos s immune stimulatory adjuvant platform builds on combinatorial use of immune agonists with distinct immune targets and mechanisms of action for the generation of therapeutic immune responses Critical to this platform techno ...

DESCRIPTION provided by applicant Diagnosis of multiple sclerosis MS rests on clinical symptoms and examinations supported by appropriate magnetic resonance imaging findings or other laboratory tests such as oligoclonal bands in cerebrospinal fluid and evoked potential testing Clinically isolated syndrome CIS is a first neurologic episode lasting at least hours possibly caused by focal ...

DESCRIPTION provided by applicant Melanoma the fastest growing cancer incidence in the world today and the American Cancer Society reports that death rates for melanoma continue to rise Alarmingly melanoma is the most common cancer in young adults under One characteristic of metastatic melanoma cells that is recognized as a potential target for new therapies is upregulation of cell surfac ...

DESCRIPTION provided by applicant Skeletal muscle atrophy is a highly prevalent condition caused by advanced age muscle disuse chronic illness critical illness and malnutrition In addition to being very common muscle atrophy has serious consequences including weakness reduced activity and quality of life falls fractures extended hospitalizatio and rehabilitation nursing home placem ...

DESCRIPTION provided by applicant More than U S patients have end stage renal disease and over utilize hemodialysis as their renal replacement modality of choice The Achilles Heel in the care of dialysis patients is the development of a functioning and durable vascular access preferably an arteriovenous fistula The annual cost of treating vascular access dysfunction totals over ...

DESCRIPTION provided by applicant According to the CDC in ischemic heart disease is the leading cause of death worldwide and in the US approximately patients died of ischemic heart disease It is well established in clinical practice that recanalization of he infarct related artery IRA using percutaneous coronary intervention PCI enhances myocardial salvage and outcomes in pa ...

DESCRIPTION provided by applicant Patients who cannot communicate with doctors nurses other health professionals and caregivers are at increased risk for having adverse medical outcomes Zubow and Hurtig reported that percent of conscious hospitalized patients and percent of intensive care unit patients were unable to independently activate standard nurse call systems Based on t ...

DESCRIPTION provided by applicant The goal of the Phase I study is to determine the feasibility of piloting a low cost Real Time Location System RTLS for use in healthcare based on a novel technology known as Near Field Electromagnetic The proposed QHealth system promises to support a number of healthcare applications such as equipment management workflow optimization hand hygiene complian ...

DESCRIPTION provided by applicant ParaTechs Corporation aims to provide researchers with advanced technology and methods to simplify procedures for laboratory animal models While actively supporting efforts to `reduce replace and refineandapos animal use ParaTechs provides safe and efficient alternatives for surgical procedures We have already brought to market a nonsurgical embryo transfe ...