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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Target Identification for Novel Small Molecule Therapeutic for Alzheimer's disease
SBC: CoPlex Therapeutics, LLC Topic: NIAABSTRACT Traditional approaches to drug development for Alzheimer s disease are becoming increasingly expensive and in many cases disappointingly unsuccessful Based on preliminary in vitro and in vivo studies we have identified a novel small molecule methyl dimethyl oxo dihydrobenzo c naphthyridine carboxylate UK that significantly decreases A production and pro in ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
A New Prostate Cancer Treatment to Improve Outcomes and Reduce Side-effects
SBC: PXALPHA, L.L.C. Topic: 102PROJECT SUMMARY ABSTRACT Among men prostate cancer is the most common non skin cancer and second leading cause of cancer death with over new diagnoses expected in Approximately of men will be diagnosed with prostate cancer in their lifetime Current treatment options for prostate cancer however have sub optimal incidences of side effects that have a significant impact on pa ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
A brief iPad based screening measure for HIV associated neurocognitive disorders
SBC: Digital Artefacts LLC Topic: 105Despite significance advances in anti retroviral treatments HIV associated neurocognitive disorder HAND remains prevalent and can affect a broad range of everyday activities An effective brief cognitive screen that could be implemented in busy HIV clinics where clinicians have limited time to provide care for patients with complex medical psychiatric and cognitive conditions has the poten ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Precision, pulmonary disease evaluation and lung cancer detection using quantitative low-dose CT
SBC: VIDA DIAGNOSTICS, INC. Topic: 102DESCRIPTION provided by applicant Lung cancer is responsible for more cancer deaths than breast prostate and colon cancers combined Minimal improvements in the five year survival rate for lung cancer have occurred over the past thirty years Recently a mortality benefit has been demonstrated for lung cancer screening using low dose computed tomography LDCT in people with high cancer risk ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
An Automated Patient Chart Error Detection System for Radiation Therapy
SBC: Infondrian LLC Topic: 101Project Summary Abstract Every year approximately severe mistreatments happen in radiation therapy Radiation therapy lawsuits rank in the top third of all medical specialties with an average of $ per claim settled or litigated The current method for detecting treatment errors is by a weekly patient chart check where each treatment record is manually reviewed on a weekly basis Thi ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
CardioPort to Enable Intracardiac Beating Heart and Minimally Invasive Open Heart Surgery
SBC: Nido Surgical, Inc Topic: NHLBIDESCRIPTIONprovided by applicantThe goal of this Fast Track STTR project is to develop a novel CardioPortTM surgical device that will enable minimally invasive beating heart repair without use of cardiopulmonary bypassCPBThere is a critical unmet need for new instruments to improve the surgical repair of heart defects in childrenCurrent best surgical practices involve either open heart surgery wit ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of PAR Pepducins for the Treatment of Atopic Dermatitis
SBC: OASIS PHARMACEUTICALS, LLC Topic: NIAMSDESCRIPTION provided by applicant Atopic dermatitis AD or severe eczema is a very common life long skin disease with of adults in the US requiring systemic therapy Clinical manifestations of AD include multiple inflamed lesions erosions accompanied by lichenification thick leathery skin fibrotic papules and severely dry skin with increased susceptibility to infection A major uncont ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Therapeutics for inflammatory bowel disease from the microbiome
SBC: SYMBIOTIX BIOTHERAPIES, INC. Topic: 300PROJECT SUMMARY ABSTRACT Interactions between the gut microbiome and the immune system have been linked to inflammatory bowel disease IBD IBD is a chronic and progressive gastrointestinal disease characterized by uncontrolled activation of the intestinal immune system resulting in severe medical complications affecting over million patients in the United States It is a disease of high u ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Simultaneous Proportional and Independent sEMG Based Hand Wrist Prosthesis Control
SBC: LIBERATING TECHNOLOGIES INC Topic: NICHDDESCRIPTION provided by applicant Surface electromyogram sEMG controlled powered hand wrist prostheses are used by upper limb amputees to return partial upper limb function Conventional transradial prostheses can use surface EMG amplitudes from the residual forearm flexors and extensors to control hand closing and opening respectively Additional degrees of freedom DoFs e g wrist rota ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Macromolecule Crystallization Screening Results Analysis
SBC: iXpressGenes, Inc. Topic: 100Project Summary Crystallization followed by subsequent structure determination is a major step in understanding the structure function relationship of macromolecules Understanding macromolecule structure has become a key part in the development of new pharmaceuticals and is a major area of NIH research Crystallization however is also the rate limiting step despite technological efforts to a ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health