Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Antibody targeting of ADAM for treatment of triple negative breast cancer

    SBC: Adecto Pharmaceuticals, Inc.            Topic: NCI

    DESCRIPTION provided by applicant Triple negative breast cancers TNBCs account for of breast cancer deaths and lack targeted therapies Drs Sonenshein Mineva and Romagnoli and their co workers recently identified the non essential cell surface protein ADAM A Disintegrin and Metalloprotease as a pivotal promoter of breast tumor growth and metastasis and validated it as a target o ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Compact CMOS-Compatible Optical Transceiver

    SBC: Physical Sciences Inc.            Topic: AF14AT13

    Physical Sciences Inc. (PSI) and the research group of Professor Richard Osgood at Columbia University propose to develop a compact optical transceiver based on devices fabricated on a complementary metal-oxide semiconductor (CMOS) platform. The recent development of novel integrated structures in silicon including waveguides, resonators, and photodetectors will enable dramatic reductions in size, ...

    STTR Phase II 2016 Department of DefenseAir Force
  3. CyberSTEPS- Cyber Skills Training with Electronic Performance Support

    SBC: Tier 1 Performance Solutions, LLC            Topic: AF16AT08

    There are many challenges in creating Air Force systems that are resilient against cyber threats. The cyber environment and its threats are highly dynamic, requiring practices and training to be dynamic as well. Cyber threats must be considered during th...

    STTR Phase I 2016 Department of DefenseAir Force
  4. Developing Therapeutics That Target RAD To Treat Leukemia and Lymphoma

    SBC: Cyteir Therapeutics, Inc.            Topic: NCI

    DESCRIPTION provided by applicant Genomic instability is a hallmark of cancer and represents a targetable vulnerability yet is underdeveloped as a therapeutic area The central goal of this Phase program is to complete the early preclinical development of a new class of new cancer therapeutics that uniquely target RAD delivering effective cancer cell selective therapy in subsets of bioma ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Development of An Integrated High Throughput Imaging and Image Analysis Platform for Muscle

    SBC: CytoInformatics LLC            Topic: NIA

    DESCRIPTION provided by applicant There is growing awareness that weakness of muscle is a significant biomedical health issue associated with many different chronic diseases and aging There are a variety of different diseases that affect muscle including muscular dystrophy fibromyalgia cerebral palsy amyotrophic lateral sclerosis and myasthenia gravis each of which carries its own uniqu ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Development of PAR Pepducins for the Treatment of Atopic Dermatitis

    SBC: OASIS PHARMACEUTICALS, LLC            Topic: NIAMS

    DESCRIPTION provided by applicant Atopic dermatitis AD or severe eczema is a very common life long skin disease with of adults in the US requiring systemic therapy Clinical manifestations of AD include multiple inflamed lesions erosions accompanied by lichenification thick leathery skin fibrotic papules and severely dry skin with increased susceptibility to infection A major uncont ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Development of Adaptive Closure Models for Large Eddy Simulations of Lean Blow-Out Conditions

    SBC: CFD Research Corporation            Topic: AF16AT14

    Next-generation turbulent combustion models must enable accurate prediction of lean blow-out and flashback for complex geometries, fuels and operating conditions relevant to the Air Force. Improved models are needed to better predict kinetically and hydr...

    STTR Phase I 2016 Department of DefenseAir Force
  8. DREAMIT- Design, Reconfigure and Evaluate Autonomous Models in Training

    SBC: Tier 1 Performance Solutions, LLC            Topic: AF15AT14

    Our Phase I work focused on improving modeling and simulations so that the impact of autonomous systems in the battlespace could be better understood. As we have trained our attention on Phase II, it has become increasingly clear that the work we are doing to improve the modeling and simulation of autonomous systems also provides significant leverage for the development of the intelligent behavior ...

    STTR Phase II 2016 Department of DefenseAir Force
  9. ENHANCING MOTION IMAGERY CLASSIFIERS BY PRINCIPAL COMPONENT FEATURE CLUSTERING

    SBC: Longshortway Inc.            Topic: AF15AT35

    LongShortWay Inc. and Northeastern University propose a family of feature reduction and ensemble classifier methods based on Principal Component and Dynamic Logic feature clustering algorithms. New methods combine feature clustering with non-linear feature reduction via manifold learning, and bagging, boosting, and stacking ensemble algorithms.

    STTR Phase II 2016 Department of DefenseAir Force
  10. High Strength and High Modulus Carbon Fiber

    SBC: VURONYX TECHNOLOGIES LLC            Topic: AF16AT27

    In this Phase 1 proposal, Vuronyx Technologies in collaboration with Georgia Institute of Technology, Atlanta (GT) intends to fabricate composite panels using high strength and high modulus carbon fibers synthesized from polyacrylonitrile (PAN) precursor...

    STTR Phase I 2016 Department of DefenseAir Force
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