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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. A chimeric protein for the selective expansion of regulatory T cells

    SBC: Sahane Biotech, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Type diabetes T D is a chronic disease caused by the autoimmune destruction of the insulin producing beta cells in the pancreas Current treatment options for T D are severely limited All patients diagnosed with T DM are placed on life long insulin therapy and the current standard of care for adult patients with T DM is intensive diabetes therapy to avoid ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Advanced Cannula Development for Coronary Sinus Access

    SBC: STRATEGIC PACING SYSTEMS LLC            Topic: NHLBI

    DESCRIPTION provided by applicant This Phase STTR will develop novel techniques for coronary sinus access The coronary sinus provides unique anatomic and physiologic proximity to all four cardiac chambers and the coronary circulation For example the coronary sinus is used for left ventricular lead insertion for biventricular pacing or cardiac resynchronization Mor than such implan ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Aminomethyl benzamides as novel anti Ebola agents

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    Ebola EBOV and Marburg MARV viruses belong to the family Filoviridae and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction with an incubation period of days Because of the safety concerns these viruses are designated as the biosafety level agents Currently there is no effective vaccine or therapeutic treatment against filoviral infection and pathogenes ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Aminopiperidines as novel anti influenza agents

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    Influenza A viruses belong to the orthomyxoviridae family with a negative sense segmented RNA genome which can cause seasonal or pandemic flu with high morbidity and significant mortality Vaccination is the most prevalent prophylactic means for controlling influenza infections However an effective vaccine usually takes at least months to develop for the circulating strains Furthermore vac ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. A mobile app to reduce treatment-related financial burden for cancer patients

    SBC: Vivor, Llc            Topic: NCI

    There is a fundamental knowledge gap in how to immediately reduce cancer patientsandapos treatment related financial burden Cancer patients pay more out of pocket for their care than those with other chronic illnesses Half of all elderly cancer patients have high treatment related out of pocket financial burden This financial burden has well defined harmful effects even among insured cancer pa ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. An Ultra filtrate perfusion bio artificial pancreas for high-density islet replacement without immunosuppression

    SBC: Norfolk Medical Products, INC.            Topic: NIDDK

    DESCRIPTION provided by applicant The Cell SafeTM is a fundamentally new approach in replacement of dysfunctional insulin producing cells in patients with diabetes by transplantation of new islets in a three dimensional scaffold embedded in a highly compatible bioengineered perfusion system that continuously supplies tissue fluid blood ultrafiltrate so that the cells ae protected from immun ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. A simple and effective diagnostic test for gastrointestinal bleeding to improve patient outcomes

    SBC: CUMBERLAND PHARMACEUTICALS INC.            Topic: 300

    DESCRIPTION provided by applicant Problem Lower gastrointestinal bleeding is a significant medical problem in the United States accounting for more than hospital admissions and tens of billions of dollars of healthcare spending annually It is common for bleeding from a single site to stop and restart multiple times The three modalities now used to diagnose and locate gastrointestina ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Caduceus Quest: A serious STEM game to promote reproductive health and STEM and health career interest

    SBC: RESILIENT GAMES STUDIO, LLC            Topic: OD

    DESCRIPTION provided by applicant The proposed Phase I STTR project will develop and test a serious game Caduceus Quest to engage youth in STEM learning facilitate reductions in sexual and reproductive health risk behaviors and promote asset development toward holistic long term well being Caduceus Quest will be a multi platform theory based role playing game in which players build up t ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Developing a method to increase HIV testing among YMSM

    SBC: RESILIENT GAMES STUDIO, LLC            Topic: NICHD

    DESCRIPTION provided by applicant Adolescents are particularly vulnerable to HIV and account for one quarter of all new infections each year Most new infections among adolescents occur among young men who have sex with men YMSM Transmission of HIV can be virtually eliminated by treatment but testing rates are low and a significant proportion of YMSM are unaware of their HIV status P ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Developing an Affordable and Pocketable POC Device for Monitoring Lithium and Sodium in Patients with Bipolar Disorder

    SBC: GlucoSentient, Inc            Topic: 102

    Project Summary Abstract The objective of this Phase I STTR project is to demonstrate feasibility of developing a selective affordable and pocket sized device to enable regular and quantitative monitoring of both Li and Na levels in the blood of patients with bipolar disorder BD which is one of the most common mental illnesses affecting over million Americans costing the healthcare syst ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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