Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. Development of An Integrated High Throughput Imaging and Image Analysis Platform for Muscle

    SBC: CytoInformatics LLC            Topic: NIA

    DESCRIPTION provided by applicant There is growing awareness that weakness of muscle is a significant biomedical health issue associated with many different chronic diseases and aging There are a variety of different diseases that affect muscle including muscular dystrophy fibromyalgia cerebral palsy amyotrophic lateral sclerosis and myasthenia gravis each of which carries its own uniqu ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications

    SBC: GENECAPTURE            Topic: CBD15C001

    The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

    STTR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  3. Innovative Mitigation of Radiation Effects in Advanced Technology Nodes

    SBC: Reliable MicroSystems, LLC            Topic: DTRA16A003

    Establish a radiation-aware analysis capability in a commercial EDA design flow that will enable first-pass success in radiation-hardened by design (RHBD) for DoD ASICs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications. Layout-aware, calibrated single-event radiation models that captur ...

    STTR Phase I 2016 Department of DefenseDefense Threat Reduction Agency
  4. Macromolecule Crystallization Screening Results Analysis

    SBC: IXPRESSGENES, INC.            Topic: 100

    Project Summary Crystallization followed by subsequent structure determination is a major step in understanding the structure function relationship of macromolecules Understanding macromolecule structure has become a key part in the development of new pharmaceuticals and is a major area of NIH research Crystallization however is also the rate limiting step despite technological efforts to a ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. SMALL MOLECULE ANTAGONISTS OF PF FOR THE TREATMENT AND PREVENTION OF HIT

    SBC: Fox Chase Chemical Diversity Center, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant We have discovered the first ever inhibitors of PF a platelet protein central to the pathophysiology of heparin induced thrombocytopenia HIT Heparin is a naturally occurring anticoagulant that prevents the formation of clots and extension of existing clots within the vasculature and major medical applications of heparin include dialysis cardiac catheteri ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Small Molecule Inhibitors of HIV Nef Virulence Factor for Treatment of HIV AIDS

    SBC: Fox Chase Chemical Diversity Center, Inc.            Topic: 100

    DESCRIPTION provided by applicant While HIV AIDS can be managed with antiretroviral drugs these agents do not clear the virus and require life long administration Recently we discovered a completely new class of compounds that interfere with the HIV virulence factor called Nef This viral protein is critical to HIV replication in vivo immune escape of HIV infected cells and AIDS progre ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. STTR Phase I: Automated object contouring methods and software for head and neck radiotherapy planning

    SBC: Quantitative Radiology Solutions LLC            Topic: BM

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is in the field of radiation therapy (RT) for head & neck cancer patients. RT planning involves designing a radiation treatment regimen so that tumors are irradiated to definitive doses while minimizing irradiation to normal structures. For devising an optimal RT plan, target tumors and critic ...

    STTR Phase I 2016 National Science Foundation
  8. STTR Phase I: CMOS-Compatible Oxide Films for Tunable Microwave Technology

    SBC: epoXtal LLC            Topic: MI

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is to reduce the cost of RF hardware, enabling wider adoption of new generations of mobile devices and services for Internet of Things applications. The project has the potential to help transform a number of sectors, including medicine and healthcare monitoring and diagnostics, transportation ...

    STTR Phase I 2016 National Science Foundation
  9. STTR Phase I: Cooperative Selection of Aptamer Pairs by Unlocking Parallel Enrichment Paths

    SBC: Proximity Biosciences LLC            Topic: BT

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to develop reliable technology for the production of aptamer pairs. Aptamers are core reagents in emerging markets, regarded as alternatives to monoclonal antibodies in therapeutics, diagnostics, and imaging. They possess several appealing qualities: Ease of in vitro synthesis, flexibl ...

    STTR Phase I 2016 National Science Foundation
  10. STTR Phase I: Corrosion Inhibition of Stainless Steel Alloys in High Temperature Chloride Salts for Concentrated Solar Power Applications

    SBC: DYNALENE INC.            Topic: CT

    The broader impact/commercial potential of this Small Business Innovation Research Phase I project is through the development of cost effective, high temperature molten salt heat transfer fluids for concentrated solar power plants that would make solar power an economical and viable source of renewable energy for mass consumption. With the worldwide growing need for energy, alternative sources of ...

    STTR Phase I 2016 National Science Foundation
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