Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until September, 2020.

  1. A New Technique for Diabetic Foot Ulcers

    SBC: Noveratech LLC            Topic: 200

    ABSTRACT Diabetes is the leading cause of nontraumatic lower extremity amputations in the United States Diabetic foot ulcers DFUs are responsible for more hospitalizations than any other diabetic complications Currently even the best available treatments achieve only a healing rate for these wounds and this healing is often only temporary with a chance of recurring Our company has ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Actuated Low Stress Endotracheal Tube Cleaner to Improve Neonate Lung Function

    SBC: ACTUATED MEDICAL, INC.            Topic: NICHD

    DESCRIPTION provided by applicant This Phase II SBIR finalizes development and clinically tests Neo ET Clear an Actuated Low Stress Endotracheal Tube ETT Cleaner to Improve Neonate Lung Function Neo ET Clear suctions mucus from mm diameter neonatal endotracheal tubes with significantly reduced deleterious impact on lung function and mechanics as compared to current methods includin ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. A mechanism based computational tool to optimize pulmonary drug delivery

    SBC: CFD Research Corporation            Topic: 300

    DESCRIPTION provided by applicant Pulmonary drug delivery has emerged as a noninvasive alternative route for the treatment of lung diseases asthma COPD CF and lung cancer In order to obtain the desired level of effectiveness and safety of the inhaled drugs an appropriate deposition on the targeted region and subsequent absorption in the targeted region is vital Multiscale multidisciplin ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. An Acoustofluidic Device for Point of Care Sputum Processing and Analysis

    SBC: Ascent Bio-Nano Technologies Inc            Topic: NHLBI

    Project Summary Asthma is a chronic lung disease that causes the airways in the lungs to become inflamed making it difficult to breathe and leading to episodes of intense coughing and wheezing The prevalence of asthma has increased rapidly over the past several decades and more than in Americans are now living with the disease While there is no cure for asthma the symptoms of the disease ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Building Materials from Scrap Tires and Waste Plastics

    SBC: PROFESSIONAL ANALYTICAL AND CONSULTING SERVICES INC            Topic: 15NCER06

    Two major waste streams, thermoplastics and used automotive tires, need a technological and economic method to decrease their entry into our environment. Both have long life-cycles as waste, causing many deleterious environmental problems. The Phase I, II , and Ill goal is to divert plastic and tire waste and its pollution away from landfills and the environment into transformational new technolog ...

    SBIR Phase I 2016 Environmental Protection Agency
  6. Chemical Optimization of a novel class of USP inhibitor for cancer treatment

    SBC: Progenra, Inc            Topic: 102

    DESCRIPTION provided by applicant Numerous regulatory proteins are tightly controlled by ubiquitin conjugation and deconjugation and deviations from this dynamic process are manifested in clinical disorders such as cancer inflammation neurodegenerative disorders and metabolic diseases The deubiquitylase DUB USP plays multiple regulatory roles all of which are pro survival antiapoptotic ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Chikungunya Recombinant Subunit Vaccine

    SBC: Hawaii Biotech, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Chikungunya virus CHIKV is an alphavirus classified as a category C priority pathogen that causes fever rash and arthralgia in humans In the past decade CHIKV outbreaks have spread beyond the endemic regions of Africa and Asia first to the islands in the Indian Ocean and most recently to the Americas The World Health Organization has reported that as ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Development of An Integrated High Throughput Imaging and Image Analysis Platform for Muscle

    SBC: CytoInformatics LLC            Topic: NIA

    DESCRIPTION provided by applicant There is growing awareness that weakness of muscle is a significant biomedical health issue associated with many different chronic diseases and aging There are a variety of different diseases that affect muscle including muscular dystrophy fibromyalgia cerebral palsy amyotrophic lateral sclerosis and myasthenia gravis each of which carries its own uniqu ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Development of Tumor Proliferation PET Tracer FLT using a Low Cost Single Dose Automatic Production and Quality Control Biomarker Generator System

    SBC: ABT Molecular Imaging            Topic: 102

    DESCRIPTION provided by applicant Worldwide a person dies from cancer every seconds Positron emission tomography PET is an effective tool that is critical in diagnosing cancer and monitoring treatment efficacy PET imaging relies on use of short lived radioisotopes Commercial distribution of the most commonly used radio tracer F FDG has resulted in patient population coverage in ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Discovery of inhibitors of BK polyomavirus

    SBC: VenatoRx Pharmaceuticals, Inc.            Topic: NIAID

    PROJECT SUMMARY Novel inhibitors of BK polyomavirus BKPyV are urgently needed to prevent the occurrence of virus induced nephropathy allograft failure and hemorrhagic cystitis following transplantation The objective of this Phase I SBIR feasibility study is to identify drug like compounds that specifically inhibit BKPyV replication During the course of this Phase I funding period we will exe ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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