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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. An Embedded Health Monitoring System for Determining Readiness of Electronic Components

    SBC: NOKOMIS INC            Topic: MDA14T001

    The MDA is in need of a robust, holistic Electronics Health Monitoring (EHM) solution that can address mission readiness concerns. Nokomis solution to this problem provides unique information to operators and maintainers and a more complete picture of component readiness. Nokomis novel methodologies for determining device health, whereby changes in unintended RF emissions signatures are leverage ...

    STTR Phase II 2016 Department of DefenseMissile Defense Agency
  2. A simple and effective diagnostic test for gastrointestinal bleeding to improve patient outcomes

    SBC: CUMBERLAND PHARMACEUTICALS, INC.            Topic: 300

    DESCRIPTION provided by applicant Problem Lower gastrointestinal bleeding is a significant medical problem in the United States accounting for more than hospital admissions and tens of billions of dollars of healthcare spending annually It is common for bleeding from a single site to stop and restart multiple times The three modalities now used to diagnose and locate gastrointestina ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Automated Object Contouring Methods & Software for Thoracic Radiotherapy Planning

    SBC: Quantitative Radiology Solutions LLC            Topic: 102

    DESCRIPTION provided by applicant In nearly million new cancer cases are estimated to occur in the US where nearly two thirds will have treatment by radiation therapy In current clinical practice organ contour delineation on medical images is still performed with low levels of automation due to lack of highly automated commercial contouring software This deteriorates therapy plann ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Biological super-resolution imaging using high-index microspheres for cancer research application

    SBC: SphereVis LLC            Topic: 400

    DESCRIPTION provided by applicant Optical microscopy is the most commonly used imaging technique in life and material sciences however the spatial resolution of any standard microscope is fundamentally limited by the diffraction of light waves which for visible light restricts spatial resolution to nm Surpassing the diffraction limit significantly impacts several disciplines such as me ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Contextual Reasoning for Object Identification

    SBC: NOVATEUR RESEARCH SOLUTIONS LLC            Topic: MDA15T001

    This Small Business Technology Transfer project will develop a mathematical framework and enabling technologies for context-aware target classification and selection for missile defense systems in the presence of counter-measures and clutter in realistic scenarios. Based on statistical relationship learning (SRL) methodology, the proposed framework can reason simultaneously about multiple entries ...

    STTR Phase I 2016 Department of DefenseMissile Defense Agency
  6. Controlled Release Polymer Structures for In Situ Chemical Oxidation of Contaminated Groundwater

    SBC: AXNANO LLC            Topic: NIEHS

    DESCRIPTION provided by applicant The EPA estimates that one out of every four Americans lives within three miles of a hazardous waste site Over brownfield sites are awaiting remediation and sites on the National Priorities List Potential Responsible Parties or the Superfund program are tasked with remediating these sites but insufficient funding and growing number of sites hav ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Developing a novel adjuvant system for therapeutic vaccines against lung cancer

    SBC: FasCure Therapeutics LLC            Topic: 102

    DESCRIPTION provided by applicant Therapeutics is focused on the development of adjuvant systems with desired immune activities for targeted indications The Companyandapos s immune stimulatory adjuvant platform builds on combinatorial use of immune agonists with distinct immune targets and mechanisms of action for the generation of therapeutic immune responses Critical to this platform techno ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Development of An Integrated High Throughput Imaging and Image Analysis Platform for Muscle

    SBC: CytoInformatics LLC            Topic: NIA

    DESCRIPTION provided by applicant There is growing awareness that weakness of muscle is a significant biomedical health issue associated with many different chronic diseases and aging There are a variety of different diseases that affect muscle including muscular dystrophy fibromyalgia cerebral palsy amyotrophic lateral sclerosis and myasthenia gravis each of which carries its own uniqu ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. development of immunodeficient rabbit models

    SBC: Celetrix LLC            Topic: NIAID

    DESCRIPTION provided by applicant Transplantation of human or animal pluripotent stem cells PSCs or their derivatives to model animals constitutes an important preclinical system to model and investigate cell survival development and differentiation in vivo and to assess the safety and efficacy of transplantation based cell therapies Immunodeficient mice are dominantly used in biomedical ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Development of novel research tools and a database for mapping human mitochondrial tRNA modifications by mass spectrometry

    SBC: Ribonova Inc.            Topic: R42

    Summary In this fast track Phase I II STTR project a novel mass spectrometry method and a matched reagent kit will be developed for mapping modified nucleotides in human mitochondrial transfer RNA mt tRNA including the most abundant modification pseudouridine which hitherto has proved to be a technical challenge because it is an isomer of uridine These new research tools will be harnessed to build ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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