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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Exploiting Natural Products-Based Therapeutics for Aflatoxin Mitigation

    SBC: CFD RESEARCH CORPORATION            Topic: CBD152003

    Aflatoxins are a paradigm among fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk forthe development of hepatocellular carcinoma. Currently, there are no known countermeasures that can selectively mitigate aflatoxin toxicity andthe available options are only symptomatic treatments. To meet this challenge, we propose to harness the microbio ...

    SBIR Phase I 2016 Department of DefenseOffice for Chemical and Biological Defense
  2. Developing a novel adjuvant system for therapeutic vaccines against lung cancer

    SBC: FasCure Therapeutics LLC            Topic: 102

    DESCRIPTION provided by applicant Therapeutics is focused on the development of adjuvant systems with desired immune activities for targeted indications The Companyandapos s immune stimulatory adjuvant platform builds on combinatorial use of immune agonists with distinct immune targets and mechanisms of action for the generation of therapeutic immune responses Critical to this platform techno ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Dental Adhesives to Prevent Recurrent Caries

    SBC: CuRE Innovations, LLC            Topic: NIDCR

    DESCRIPTION provided by applicant Bacterial related marginal decay is the top reason for failure and retreatment of resin based composite restorations RBCs Retreatment of these restorations costs both the patients and insurance companies billions of dollars per year The weak point of the system is the zone known as the hybrid layer where the adhesive bonds the RBC to the dentin There are ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Novel mechanism for the treatment of epilepsy: New Vitamin K analogs target energetics and have low toxicity due to excellent specificity and low dose requirements compared to current therapies

    SBC: NEUROENE THERAPEUTICS INC            Topic: 106

    DESCRIPTION provided by applicant Epilepsy is the th most common neurological disorder with in people developing epilepsy the occurrence of more than one unprovoked seizure at some point in their lifetime Unfortunately of all patients have intractable medication resistant epilepsy Thus new anti epileptic drugs AEDs that target alternative mechanisms of action are needed ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Long non-coding RNA signatures to classify multiple sclerosis

    SBC: IQuity Labs, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Diagnosis of multiple sclerosis MS rests on clinical symptoms and examinations supported by appropriate magnetic resonance imaging findings or other laboratory tests such as oligoclonal bands in cerebrospinal fluid and evoked potential testing Clinically isolated syndrome CIS is a first neurologic episode lasting at least hours possibly caused by focal ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Nitric oxide releasing nanomatrix wrap to enhance dialysis fistula maturation

    SBC: ENDOMIMETICS LLC            Topic: 400

    DESCRIPTION provided by applicant More than U S patients have end stage renal disease and over utilize hemodialysis as their renal replacement modality of choice The Achilles Heel in the care of dialysis patients is the development of a functioning and durable vascular access preferably an arteriovenous fistula The annual cost of treating vascular access dysfunction totals over ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. An H/F/X/Y Fast-MAS NMR Probe Particularly for Alzheimer’s and Cancer Research

    SBC: DOTY SCIENTIFIC, INC.            Topic: 400

    DESCRIPTION provided by applicant More than of current drugs and a much greater fraction of those in development are fluorinated including such block busters as Prozac Lipitor and Ciprobay Steady progress over the past decade has shown magic angle spinning MAS solid state NMR ssNMR to be arguably the most powerful analytical tool for studying macro molecular structures and their ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. A Quad-Fast-MAS probe for Dramatically Improved Biomolecular Structure Determinations

    SBC: DOTY SCIENTIFIC, INC.            Topic: 400

    DESCRIPTION provided by applicant A Quad Fast MAS probe for Dramatically Improved Biomolecular Structure Determinations Abstract The last years have seen steady progress in applying magic angle spinning MAS NMR to an increasingly wide range of applications in structural biology However the methods are all far from routine and often require mg of a concentrated sample that is extrem ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel Lipotherapy to Reduce Infarct Size Following Myocardial Infarction

    SBC: ENDOPROTECH, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant According to the CDC in ischemic heart disease is the leading cause of death worldwide and in the US approximately patients died of ischemic heart disease It is well established in clinical practice that recanalization of he infarct related artery IRA using percutaneous coronary intervention PCI enhances myocardial salvage and outcomes in pa ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. A Next Generation, Low Cost Tracking System for Healthcare

    SBC: Q-Track Corporation            Topic: 600

    DESCRIPTION provided by applicant The goal of the Phase I study is to determine the feasibility of piloting a low cost Real Time Location System RTLS for use in healthcare based on a novel technology known as Near Field Electromagnetic The proposed QHealth system promises to support a number of healthcare applications such as equipment management workflow optimization hand hygiene complian ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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