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DOE NE-75 is seeking advanced radioisotope space power conversion systems in the 10-500 watt electric range to support NASA science missions. Current radioisotope thermoelectric generators (RTGs) for these applications are very reliable, but extremely inefficient. Due to the cost and limited availability of radioisotope fuel, robust and reliable dynamic power conversion systems are needed that can ...

DESCRIPTION provided by applicant Cardiovascular diseases and Asthma affects between and million people in the United States including million children during the past years its incidence worldwide has doubled Asthma is responsible for million person days of restricted activity and deaths per year amounting to $ billion in direct heath related costs there is uncertainty about the specific factors ...

There is an unmet demand for ultra-low-power, ultra-compact and low-cost radios to address emerging sensing and communication needs for military and commercial applications such as IoT/IoE. To overcome the limitations in existing bulky and power hungry radios, we propose a disruptive solution by integration of a nano-scaled THz transceiver, on-chip antenna, and energy harvesting circuits in a form ...

DESCRIPTION provided by applicant Problem Lower gastrointestinal bleeding is a significant medical problem in the United States accounting for more than hospital admissions and tens of billions of dollars of healthcare spending annually It is common for bleeding from a single site to stop and restart multiple times The three modalities now used to diagnose and locate gastrointestina ...

The goal of this project is to develop a quantitative molecular breast imaging PET QMBI PET scanner to improve the way in which breast cancer therapies are matched to individual patients by providing evaluation of therapy efficacy during the window of opportunity between diagnosis and surgical resection More than women in the US with invasive disease start therapy for breast cancer each ...

DESCRIPTIONprovided by applicantThe primary goal of this proposal is to develop and finalize configuration of a rapid molecular diagnostics test to predict antibiotic resistance of th major human uropathogensEscherichia coliKlebsiella pneumoniaeEnterobacter spp and Pmirabilisby determining the sub species clonal identityclonotypeof the infecting bacteria directly from urine samplesCurrentlythe emp ...

There are many challenges in creating Air Force systems that are resilient against cyber threats. The cyber environment and its threats are highly dynamic, requiring practices and training to be dynamic as well. Cyber threats must be considered during th...

DESCRIPTION provided by applicant Therapeutics is focused on the development of adjuvant systems with desired immune activities for targeted indications The Companyandapos s immune stimulatory adjuvant platform builds on combinatorial use of immune agonists with distinct immune targets and mechanisms of action for the generation of therapeutic immune responses Critical to this platform techno ...

Next-generation turbulent combustion models must enable accurate prediction of lean blow-out and flashback for complex geometries, fuels and operating conditions relevant to the Air Force. Improved models are needed to better predict kinetically and hydr...