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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. An Advanced Biosensor for Molecular Interaction Studies.

    SBC: MOLECULAR SENSING, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Molecular interactions form the foundation of biology and chemistry. They are central to life itself and determine catalytic activity, cellular function, and therapeutic efficacy. The vast majority of diagnostic procedures depend on some type of specific molecular interaction. Therefore, the ability to perform pure liquid-phase molecular binding analysis at hi ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. A universal framework for non-deteriorating time-domain numerical algorithms in Maxwell's electrodynamics

    SBC: COMPUTATIONAL SCIENCES LLC            Topic: A13AT008

    The project will remove a key difficulty that currently hampers many existing methods for computing unsteady electromagnetic waves on unbounded regions. Numerical accuracy and/or stability may deteriorate over long times due to the treatment of artificial outer boundaries. We propose to develop a universal algorithm and software that will correct this problem by employing the Huygens'principl ...

    STTR Phase I 2013 Department of DefenseArmy
  3. Construction of 3-D Terrain Models from BIG Data Sets

    SBC: Scalable Algorithmics USA            Topic: A13AT005

    The objective of this proposal is to design, analyze, and implement scalable algorithms for analysis-driven construction of high-resolution 3D terrain models from BIG terrain data sets, and to build a software infrastructure for making analysis-prepared terrain models available to data consumers on multiple platforms. Analysis-driven modeling means that the construction of the model is influence ...

    STTR Phase I 2013 Department of DefenseArmy
  4. Controlling mechanical signal transduction to treat osteoarthritis

    SBC: Cytex Therapeutics, Inc.            Topic: NIA

    DESCRIPTION (provided by applicant): Controlling mechanical signal transduction to treat osteoarthritis Abstract The TRPV4 calcium (Ca++) permeable ion channel has been shown to be expressed and functional in chondrocytes, the cells responsible for the maintenance of cartilage in weight-bearing joints. Trauma of joints with subsequent damage of cartilage, as well as chronically increased joint loa ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Cryodeposit Mitigation and Removal Techniques for Radiometric Calibration Chambers

    SBC: OPTICAL SCIENCES CORPORATION            Topic: AF12BT10

    ABSTRACT: Optical Sciences Corporation (OSC) and the University of Alabama in Huntsville"s Center for Applied Optics (UAH/CAO) will demonstrate the feasibility and present a plan for developing optical instrumentation for the monitoring, mitigation, and removal of cryodeposits accumulated on optical and mechanical surfaces in cryogenic-vacuum radiometric calibration chambers. OSC will investigat ...

    STTR Phase I 2013 Department of DefenseAir Force
  6. Droplet-Based Automation of Complex Workflows for Synthetic Biology

    SBC: ADVANCED LIQUID LOGIC            Topic: ST12B003

    Large-scale genome engineering represents a broad group of technologies, all of which stand to impact the manufacturing of a range of biological and chemical products. While the power of these methods to increase the production of biologically-driven manufacturing processes has been previously demonstrated, they are often developed and optimized toward a single target, or single methodology. Curre ...

    STTR Phase I 2013 Department of DefenseDefense Advanced Research Projects Agency
  7. Electro-Optic Terminal Protection for Radar Systems Phase II

    SBC: ARC TECHNOLOGY LLC            Topic: MDA10T001

    The potential threat of directed energy weapons (DEW) and other high peak power electromagnetic transient signals require radar systems to implement front door protection against high power signals. Fast ultra wideband (UWB) and high power microwave (HPM) signals are not successfully blocked by most current protection technologies. The Phase I work demonstrated a quasi-passive, solid state e ...

    STTR Phase II 2013 Department of DefenseMissile Defense Agency
  8. Evaluation of a new class of molecules for treating MRSA infective endocarditis

    SBC: AGILE SCIENCES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Patients with infective endocarditis (IE) have a poor prognosis with one third of the patients succumbing to the infection within the first year. Treatments for endocarditis involve antibiotic therapy and/or surgery that cost upwards of 100,000 per patient; however, many cases do not respond to the antibiotic treatment and surgery poses high risks. Cases of en ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. First-Principles-Based Framework for Discovery and Design of Sustainable Non-Rare-Earth High-Temperature Alloy Systems

    SBC: CFD RESEARCH CORPORATION            Topic: OSD12T06

    In this STTR Phase I project, CFD Research Corporation and University of Nebraska at Omaha will develop a preliminary computationally-driven first-principles framework for discovery and design of non-RE-containing alloys for high temperature applications. While rare-earth (RE) based alloys have played a pivotal role in modern defense and high-tech industry, sustainability of RE-based materials is ...

    STTR Phase I 2013 Department of DefenseAir Force
  10. Fluorescence Intensity-based Scoring of Macromolecule Crystallization Plates

    SBC: iXpressGenes, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Crystallization, followed by subsequent structure determination, is a major step in understanding the structure- function relationship of macromolecules. Understanding macromolecule structure has become a key part in the development of new pharmaceuticals, and is a major area of NIH research. Crystallization however is also the rate limiting step, despite techn ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
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