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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. STTR Phase I:Refrigerant Ionic liquid Separation

    SBC: ICONIUM ENGINEERING COMPANY            Topic: CT

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to provide the refrigerant industry with the first commercial designs for separating complex, multi-component, azeotropic refrigerant mixtures for economical recycling. The American Innovation and Manufacturing Act authorizes the Environmental Protection Agency (EPA) to phase down prod ...

    STTR Phase I 2023 National Science Foundation
  2. STTR Phase I:Multifunctional Lipid Nanoparticle Delivery System for Targeted Delivery of Vascular RNA Therapeutics

    SBC: Richard Fisher            Topic: BM

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is that the proposed delivery system will advance many RNA therapeutic solutions to address intimal hyperplasia (IH) and other vascular conditions. Vascular disease is the most common disease pathology in the US, costing the country’s healthcare system over $437 billion dollars annually. Bec ...

    STTR Phase I 2023 National Science Foundation
  3. Development of an Orally Available Therapeutic for Neutralizing C. difficile Toxin B

    SBC: NECTAGEN INC            Topic: NIAID

    Infection with the bacterium C. difficile is the most common and increasingly prevalent cause of diarrhea. In the United States, cases of C. difficile infection (CDI) are estimated to number 500,000 annually and to result in an estimated 15,000 to 30,000 deaths. The cost of these cases is thought to exceed $4.8 billion annually. CDI continues to cause discomfort, serious illness and sometimes deat ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Real-time Multimodal Diffuse Reflectance and Polarization Imaging Based Nerve Identification in Surgical Field of View

    SBC: YAYA SCIENTIFIC LLC            Topic: NIBIB

    PROJECT SUMMARY We propose to develop a novel non-contact, label-free multimodality imager that provides real-time intraoperative identification of nerves within the surgical field-of-view to facilitate the prevention of unintended nerve damage (termed iatrogenic nerve injury) during surgical procedures, as they are a major source of postsurgical complications, e.g., chronic pain. In the United St ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. STARTUP Central

    SBC: CONTINUUM EDUCATIONAL TECHNOLOGIES, PBC            Topic: 500

    PROJECT SUMMARY Continuum Educational Technologies’ (Continuum) will work with the University of Kansas (KU) on the proposed I-RED program entitled Smart Tools to Accelerate Research Translation by Uplifting Participants for the Central IDeA State Region (STARTUP Central) program to stimulate technological innovation in the IDeA state regions by addressing the entrepreneurial educational needs o ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Optimizing Small Molecule Mechanomimetics to Treat Age-related Osteoporosis.

    SBC: OAK RIDGE THERAPEUTIC DISCOVERY LLC            Topic: NIA

    Abstract There is an unmet need to develop treatments for senile osteoporosis, a disorder characterized by an age-related reciprocal decrease in osteogenesis and increase in bone marrow fat. Senile osteoporosis resembles disuse osteopenia, suggesting its pathogenesis involves impaired bone mechanosensing. We discovered that the polycystin heterotrimeric complex (1PC1+3PC2) functions as a mechanose ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Developing a selective TRPC3 ion channel inhibitor for epilepsy treatment

    SBC: SEAK Therapeutics, LLC            Topic: 106

    Project SummaryEpilepsy is one of the most common brain disorders. Current drugs have limited efficacy. Identifying new targeted drugs that can be used as safer, more effective therapies is in urgent unmet need. Selective inhibition of the transient receptor potential canonical 3 (TRPC3) emerges as a novel strategy to impede epilepsy. However, the currently best selective TRPC3 inhibitor, Pyr3, ha ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  8. STTR Phase I:Innovative dispersion technology for the sustainable repurposing of off-spec and recycled carbon fiber into low-cost, defect-free, nonwoven fabrics

    SBC: ENDEAVOR COMPOSITES, INC.            Topic: AM

    The Broader impact of this Small Business Technology Transfer (STTR) Phase I project is to intercepting landfill-destined carbon fiber – designated as off-spec fibers - and repurpose it into sustainable nonwoven fabrics. Off-spec carbon fiber constitutes 30% of carbon fiber production. These sustainable fabrics will be categorized based on their performance characteristics into multiple tiers th ...

    STTR Phase I 2022 National Science Foundation
  9. STTR Phase I:Feasibility of multi-layer microplate test for rapid detection and enumeration of Salmonella spp. in raw poultry and processing environment samples

    SBC: SECURE FOOD SOLUTIONS, INCORPORATED            Topic: BT

    The broader impact of this Small Business Technology Transfer (STTR) Phase I project will be reduced incidence of infections and outbreaks from Salmonella, one of the most frequently reported bacterial causes of food-borne illness in the US. Each year Salmonella causes over 1.35 M illnesses and 26,500 hospitalizations, with 20 percent of infections attributable to poultry. Given that the number of ...

    STTR Phase I 2022 National Science Foundation
  10. STTR Phase I:Digital Mental Health for Children and Adolescents

    SBC: BlueWonder Creative, LLC            Topic: DH

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is improved children’s mental and behavioral health via the creation of a platform that unifies the silos of healthcare and education to put children and families first.Due in part to the current pandemic, there is an increased need to support children’s mental and behavioral health.The en ...

    STTR Phase I 2022 National Science Foundation
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