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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of an Orally Available Therapeutic for Neutralizing C. difficile Toxin B

    SBC: NECTAGEN INC            Topic: NIAID

    Infection with the bacterium C. difficile is the most common and increasingly prevalent cause of diarrhea. In the United States, cases of C. difficile infection (CDI) are estimated to number 500,000 annually and to result in an estimated 15,000 to 30,000 deaths. The cost of these cases is thought to exceed $4.8 billion annually. CDI continues to cause discomfort, serious illness and sometimes deat ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Real-time Multimodal Diffuse Reflectance and Polarization Imaging Based Nerve Identification in Surgical Field of View

    SBC: YAYA SCIENTIFIC LLC            Topic: NIBIB

    PROJECT SUMMARY We propose to develop a novel non-contact, label-free multimodality imager that provides real-time intraoperative identification of nerves within the surgical field-of-view to facilitate the prevention of unintended nerve damage (termed iatrogenic nerve injury) during surgical procedures, as they are a major source of postsurgical complications, e.g., chronic pain. In the United St ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. STARTUP Central

    SBC: CONTINUUM EDUCATIONAL TECHNOLOGIES, PBC            Topic: 500

    PROJECT SUMMARY Continuum Educational Technologies’ (Continuum) will work with the University of Kansas (KU) on the proposed I-RED program entitled Smart Tools to Accelerate Research Translation by Uplifting Participants for the Central IDeA State Region (STARTUP Central) program to stimulate technological innovation in the IDeA state regions by addressing the entrepreneurial educational needs o ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  4. Optimizing Small Molecule Mechanomimetics to Treat Age-related Osteoporosis.

    SBC: OAK RIDGE THERAPEUTIC DISCOVERY LLC            Topic: NIA

    Abstract There is an unmet need to develop treatments for senile osteoporosis, a disorder characterized by an age-related reciprocal decrease in osteogenesis and increase in bone marrow fat. Senile osteoporosis resembles disuse osteopenia, suggesting its pathogenesis involves impaired bone mechanosensing. We discovered that the polycystin heterotrimeric complex (1PC1+3PC2) functions as a mechanose ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  5. Developing a selective TRPC3 ion channel inhibitor for epilepsy treatment

    SBC: SEAK Therapeutics, LLC            Topic: 106

    Project SummaryEpilepsy is one of the most common brain disorders. Current drugs have limited efficacy. Identifying new targeted drugs that can be used as safer, more effective therapies is in urgent unmet need. Selective inhibition of the transient receptor potential canonical 3 (TRPC3) emerges as a novel strategy to impede epilepsy. However, the currently best selective TRPC3 inhibitor, Pyr3, ha ...

    STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Electrochemical Biosensor Based Rapid Diagnostic Platform for Quantitative Detection Controlled Substance Related Metabolites

    SBC: FOOTHOLD LABS INC            Topic: AFX20DTCSO1

    Electrochemistry-based sensors have been shown to provide reliable, rugged, low-cost solutions for analyte detection. Common uses for electrochemical sensors are smoke and carbon monoxide detectors, industrial gas sensors, and insulin monitors. However, e

    STTR Phase II 2023 Department of DefenseAir Force
  7. Lightweight Multifunctional EMI-shielding Coatings Enabled by Domestic, Sustainable, & Low-Cost Carbon Nanotubes

    SBC: SKYNANO LLC            Topic: AFX23DTCSO1

    Electromagnetic Interface (EMI) Shielding is critical for maintenance of critical infrastructure and to prevent from external signals from disrupting electronics devices.  State of the art EMI shielding includes heavy metal-based materials, which add mass

    STTR Phase I 2023 Department of DefenseAir Force
  8. Domestic source of semiconducting carbon nanotubes for advanced chemical sensors

    SBC: AMERICAN NANOTECHNOLOGIES INC            Topic: AFX23DTCSO1

    Semiconducting carbon nanotubes (s-CNTs) have been used to build thin, flexible sensors relevant to the DoD mission. These include both physical sensors, such as stress/strain and temperature sensors, and chemical sensors, such as biomarker or toxic compo

    STTR Phase I 2023 Department of DefenseAir Force
  9. A New Rapid Conversion Technology for High Volume, Low Cost Carbon Fiber

    SBC: ReMaxCo Technologies, LLC            Topic: AF21ATCSO2

    Carbon fiber is now used extensively in military vehicles, structures and equipment, and its use will only expand due to its combination of light weight and high strength. However, the challenge of widespread adoption both in the military and in the comme

    STTR Phase I 2022 Department of DefenseAir Force
  10. Keeping Cool without Fossil Fuel- concentrated solar powered air-conditioning for reduced power consumption in austere operating conditions and at fixed USAF bases

    SBC: HyperBorean, LLC            Topic: AF21BTCSO1

    HyperBorean has developed air cooling solutions which operate off-grid and are powered by sources of no-cost heat in lieu of electricity. Sources of heat input for HyperBorean’s systems include concentrated solar and the waste heat generated by internal c

    STTR Phase I 2022 Department of DefenseAir Force
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