Award Data

DESCRIPTION (provided by applicant): Our long-term research goal is to develop an ophthalmic, nanofiber-based, biodegradable device that will provide extended release of therapeutic agents to the posterior segment of the eye via transscleral and intravitr eal approaches. This platform device will address the major technical problem in the treatment of posterior eye diseases (diabetic retinopathy, ...

DESCRIPTION (provided by applicant): The Advanced Biofidelic Lower Extremity Kids prosthesis (ABLE Kids) project will advance the state-of-the-art of pediatric prosthesis systems by advancing the demonstrably successful Phase I device and refining it intoan ultracompact and lightweight form factor suitable for pediatric use. Through the support of the Shriner's Hospitals in Salt Lake City, U ...

Use of a new noninvasive test for the accurate early detection of preeclampsia is proposed as a tool to screen women during early stages of pregnancy. Preeclampsia affects 10% of the 4 million pregnancies in the U.S. each year and is the leading cause of maternal and neonatal medical complications and death. There is currently no means of detecting preeclampsia prior to onset of clinical symptoms ...

PROJECT SUMMARY / ABSTRACT This proposal will result in a major new clinical decision support software system, Acuity, which will assist Behavior Analysts (BAs) and Behavior Technicians (BTs) in the delivery of Applied Behavior Analysis (ABA), which is the leading treatment for autism. This is a proposal to develop software and perform a functional impact and implementation outcomes study on 34 BA ...

DESCRIPTION (provided by applicant): Clinical dilemma: Recent advances in biologic therapies for rheumatic diseases provide a means for more profound disease management. Proper diagnosis is a necessary aspect of choosing the proper biologic therapy. While disease diagnosis, based on clinical findings and laboratory tests, is effective in a significant number of patients, it can be problematic in ...

Project Summary AbstractThe objective of this proposal is to transform a hand held surgical robotic system for transurethral laser prostate surgery from a lab prototype into a commercial productThe system will feature needle sized arms deployed through the endoscope port and will enable independent tissue manipulationlaser aimingand visualizationmaking surgery more accurate and ef cientClinical si ...

The long range goal of this fast track research application is to improve healthcare quality and reduce healthcare costs nationwide among those at risk for medication related hospitalizationThe specific objective of this proposed research is to develop an algorithm that uses existing electronic health information to efficiently identify patients at risk of medication related hospitalization so tha ...

The long-range goal of this fast-track research application is to improve healthcare quality and reduce healthcare costs nationwide among those at risk for medication-related hospitalization. The specific objective of this proposed research is to develop an algorithm that uses existing electronic health information to efficiently identify patients at risk of medication-related hospitalization so t ...

THE DISPOSAL OF MUNICIPAL SOLID WASTE (MSW) IS A COSTLY PROBLEM FOR ALL MUNICIPALITIES. THE U.S. ENVIRONMENTAL PROTECTION AGENCY HAS RECOMMENDED THAT SOURCE REDUCTION, RECYCLING, VOLUME REDUCTION, AND LANDFILLING BE APPLIED, IN THAT ORDER, IN THE TREATMENT OF MSW. RECYCLING HAS RECENTLY BECOME A MAJOR COMPONENT OF MUNICIPAL WASTE MANAGEMENT PROGRAMS. HIGH COSTS OF LABOR INTENSIVE CURBSIDE RECYCLIN ...

DESCRIPTION (Applicant's Abstract): The investigators have developed a plasmid vector that expresses the normal human alpha-1 antitrypsin (AAT) gene in human respiratory epithelium when delivered as a plasmid-cationic liposome complex. In subjects with inherited AAT deficiency, they showed that liposome mediated transfer of the normal AAT gene to the nasal respiratory epi ...