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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Bacitracin derivative for systemic use

    SBC: AUREOGEN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The number of patients treated for antibiotics-resistant infections has increased drastically in recent years. What started as a problem primarily associated with hospital-acquired Enterococcus infections, has not only moved into the general community, but also grown to include a number of widespread and serious pathogens. Drug-resistant Streptococci, Staphyloc ...

    SBIR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  2. A biodegradable ophthalmic drug delivery device

    SBC: Notus Laboratories, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Our long-term research goal is to develop an ophthalmic, nanofiber-based, biodegradable device that will provide extended release of therapeutic agents to the posterior segment of the eye via transscleral and intravitr eal approaches. This platform device will address the major technical problem in the treatment of posterior eye diseases (diabetic retinopathy, ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  3. A biologically-inspired, interactive digital device to introduce K12 students to computational neuroscience

    SBC: BACKYARD BRAINS INCORPORATED            Topic: 500

    PROJECT SUMMARY Understanding the brain is a profound and fascinating challenge, captivating the scientific community and the public alike. The lack of effective treatment for most brain disorders makes the training of the next generation of neuroscientists, engineers, and physicians a key concern. However, much of neuroscience is perceived to be too difficult to be taught in school. Having alread ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  4. A biosensor to detect ERE-binding proteins in cancer

    SBC: IA, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Biosensors provide rapid data containing information on molecular interactions that are not easily available using equilibrium assays or histochemical methods. This study will be the first of a series with long-term ob

    SBIR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. ABLE Kids II- Advanced Biofidelic Lower Extremity Kids Prosthesis II

    SBC: ORTHOCARE INNOVATIONS LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): The Advanced Biofidelic Lower Extremity Kids prosthesis (ABLE Kids) project will advance the state-of-the-art of pediatric prosthesis systems by advancing the demonstrably successful Phase I device and refining it intoan ultracompact and lightweight form factor suitable for pediatric use. Through the support of the Shriner's Hospitals in Salt Lake City, U ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Accurate Early Detection of Preeclampsia

    SBC: ARBOGAST PHARMACEUTICALS, INC.            Topic: N/A

    Use of a new noninvasive test for the accurate early detection of preeclampsia is proposed as a tool to screen women during early stages of pregnancy. Preeclampsia affects 10% of the 4 million pregnancies in the U.S. each year and is the leading cause of maternal and neonatal medical complications and death. There is currently no means of detecting preeclampsia prior to onset of clinical symptoms ...

    SBIR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  7. Accurate Prostate Cancer Diagnosis for Active Surveillance Patients Using a Novel

    SBC: ProDevice Medical Supplies and Equipment LLC            Topic: NCI

    Project Abstract Active surveillance (AS) is becoming more accepted as a reasonable treatment option for men with low-risk prostate cancer (i.e. Gleason score 6, clinical stage T2a, PSA lt 10). Many AS protocols at major institutions call for a prostate saturation biopsy after initial diagnosis to confirm that the patient has no areas of higher-risk prostate cancer. For most patients who underwent ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. A chemoenzymatic technology for the efficient synthesis of novel cryptophycins

    SBC: ALLUVIUM BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The cryptophycins are a structurally diverse class of polyketide/non-ribosomal peptide natural products that possess potent anticancer activity. However, despite this impressive activity, the development of the cryptophycins into a beneficial cancer chemotherapeutic agent has suffered from clinically significant neurotoxicity that correlates with treatment. Non ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. A circular array desktop ultrasound tomography system for cross sectional imaging of small animals

    SBC: Sonamed Technologies, LLC            Topic: 100

    The long term goal of the proposed project is the development of a desktop circular array Small Animal Ultrasound Tomography System SAUTS to produce high resolution cross sectional diagnostic images of mice and other small laboratory animals The SAUTS images will look familiar to the radiologist resembling those produced by Micro CT or MRI They will be easy to interpret as the circular tomog ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. A Commercially-Viable MEMS-based Ultrasonic Volume Flow Sensor

    SBC: Sonetics Ultrasound, INC            Topic: NIBIB

    DESCRIPTION (provided by applicant): The goal of the proposed program is to address several technical feasibility questions (in Phase I), and then demonstrate (in a subsequent Phase II) a compact affordable device for operator-independent monitoring of blood volume flow, particularly in the setting of hemodialysis treatment for those with end-stage renal disease (ESRD). Phase I specific aims will ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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