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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Accelerate Adoption of Galaxy Pro in the Biomedical Research Marketplace

    SBC: GalaxyWorks LLC            Topic: NHGRI

    Project Summary Galactic Core LLC aims to develop a robust, scalable, and managed service for performing enterprise-grade biomedical data analysis. The service will be based on the popular open-source Galaxy application (​https://galaxyproject.org/​), offering unlimited data storage and compute capabilities with an extremely powerful, flexible, and collaborative environment for analyzing data. ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A Chaperonin/Osmolyte Protein Folding Screen- STTR Phase I

    SBC: EDGE BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): One of the largest bottlenecks in high-throughput protein structure determination (structural genomics) and in subsequent drug targeting (pharmocogenomics) is the acquisition of soluble correctly folded functional protein products. Unfortunately, a large amount of the protein expression systems that are commonly used yield insoluble or soluble misfolded protein ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  3. A daily client check-in system for outpatient substance abuse treatment

    SBC: COG ANALYTICS, LLC            Topic: NIDA

    Abstract Alcohol and illicit drug use remain highly prevalent in the US, and epidemiological surveillance surveys estimate that over 20.6 million individuals (~ 8% of the US population) meet standard diagnostic thresholds for substance use disorders (SAMHSA, 2011). Outpatient substance abuse treatment is the predominate method of treatment in the US for SUDs, typically involving intermittent cont ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A dual-polarized Doppler Radar system for fall detection in an indoor environment

    SBC: MS Technologies Corporation            Topic: NIA

    DESCRIPTION provided by applicant Falls are a leading cause of injuries and deaths among older adults OAs and will be an increasing public health concern given projections of future increases in the number of OAs in the US Fall detection and or surveillance systems are needed to enhance an OAandapos s confidence and independence and to facilitate rapid post fall responses This project wil ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Advanced Software for Enabling Quantitative 3D Stress Echocardiography

    SBC: IGI TECHNOLOGIES, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Through more than 5 years of research, we have developed a new cardiovascular procedure termed quantitative three-dimensional (3D) stress echocardiography (echo). Because of exceedingly high computational demands, the procedure remains clinically nonviable despite our mature academic research. The objective of this STTR project is to remove the computation bott ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  6. A Global Test of Hemostatic Risk

    SBC: Haematologic Technologies, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Although the vast majority of patients who suffer from venous or arterial thrombosis have haemostatic systems that fall within the "normal" range of routine screening tools such as PT, aPTT, and factor assays, thrombosis is the major cause of death in Western countries. In contrast, the propensity to bleed (i.e., hemophilia) is more easily diagnosed by traditio ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. A Global Test of Hemostatic Risk

    SBC: Haematologic Technologies, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Phase I funding for this project supported successful studies that were aimed at demonstrating the feasibility of developing an easy to use, global test in the arena of clinical hemostasis that would be sensitive to antithrombotic drugs, bleeding disorders and thrombotic pathologies. This test comprises a measurement of the rate of thrombin generation and/or to ...

    STTR Phase II 2007 Department of Health and Human ServicesNational Institutes of Health
  8. AIDen: An AI-empowered detection and diagnosis system for jaw lesions using CBCT

    SBC: MS Technologies Corporation            Topic: NIDCR

    Dental CBCT is a 3D imaging modality widely adopted to help dentists detect and diagnose jaw lesions. Due to minimum information loss (compared to conventional 2D radiography) and low radiation exposure (compared to conventional CT), it has become the “go-to” radiographic technique in various dental fields. Gaps: Accompanying the clear benefits of dental CBCT is an overwhelming amount of 3D da ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Alpha-1 Antitrypsin Gene Therapy for Cystic Fibrosis

    SBC: Generx+, Inc.            Topic: N/A

    DESCRIPTION (Applicant's Abstract): The investigators have developed a plasmid vector that expresses the normal human alpha-1 antitrypsin (AAT) gene in human respiratory epithelium when delivered as a plasmid-cationic liposome complex. In subjects with inherited AAT deficiency, they showed that liposome mediated transfer of the normal AAT gene to the nasal respiratory epi ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  10. Aminonaphthyridine compounds as potential therapeutics for lung and thyroid cancers

    SBC: KinaRx, LLC            Topic: 102

    Over the past three decades a growing number of cancer-driving protein kinases have been successfully targeted as reflected in the approval of 49 kinase inhibitors by the Food and Drug Administration (FDA). Recent approval of the first tyrosine kinase inhibitor (Larotrectinib) for treatment of any cancer bearing mutation in neurotrophic receptor kinase validated a novel paradigm of precision targe ...

    STTR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
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