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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Advanced Diagnostic for Performance and Combustion Characterization in Rotational Detonation Rocket Engine (RDRE)

    SBC: Exo-Atmospheric Technologies LLC            Topic: AF19AT011

    Rotating Detonation Rocket Engines (RDRE)are being developed to take advantage of the near instantaneous heat release potential of detonation waves versus conventional deflagration-based chemicalreactions in combustion applications. However, the detonation product environment is extreme and current instrumentation to measure wall / surface conditions within the detonation chamber are lacking. Thep ...

    STTR Phase I 2019 Department of DefenseAir Force
  2. Power-Dense Electrostatic Rotating Machines

    SBC: C-Motive Technologies, Inc.            Topic: N19AT007

    Next-generation naval ships will require electric machinery with at least 50% greater power density than is available today. Such machines must deliver up to 10s of MW at 100-200 rpm with very high energy efficiency, extremely low noise signature, and reasonable cost. Electrostatic machine technology is often overlooked but is perfectly suited to achieving these goals. C-Motive Technologies propos ...

    STTR Phase I 2019 Department of DefenseNavy
  3. Integrated system for field, clinic and laboratory preparation of biological specimens for microscopy

    SBC: Microscopy Innovations, LLC            Topic: DHP16C004

    Biological tissues collection is problematic and risky even under ideal conditions; when collection occurs in remote locations, or by minimally- trained personnel, as may occur in response to an emerging disease threat, risks are magnified. This proposal addresses this issue by developing a Field Fixation Unit (FFU) for specimen collection that utilizes single-use capsules pre-loaded with fixative ...

    STTR Phase II 2018 Department of DefenseDefense Health Program
  4. Hierarchical, Layout-Aware, Radiation Effects Tools Vertically Integrated into an EDA Design Flow for Rad-Hard by Design

    SBC: Reliable MicroSystems, LLC            Topic: DTRA16A003

    The goal of this workis to establish a radiation-aware capability in a commercial EDA design flow that will enable first-pass success in radiation resiliency for DoD ASIC designs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications.Such an integrated capability does not presently exist.The ...

    STTR Phase II 2018 Department of DefenseDefense Threat Reduction Agency
  5. Enabling point of care molecular diagnostics by developing an adaptive PCR instrument and on demand kit reagents

    SBC: BIOVENTURES, INC            Topic: 172

    Because of its high sensitivity polymerase chain reaction PCR is the gold standard for the diagnosis of many infectious diseases but generally only implemented in well equipped laboratories One of the major roadblocks for expanding PCR to point of care markets is the lack of simple robust single tube PCR designs which preserve its laboratory based high sensitivity and specificity In this F ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. A Novel Strategy to Identify Substances that Improve Mitochnodrial Fitness

    SBC: CYTEGEN CORP            Topic: NIA

    Project Summary Abstract Mitochondrial dysfunction causes mitochondrial diseases and is tightly linked to aging and neurodegenerative disorders such as Parkinsonandapos s and Alzheimerandapos s Recent discoveries support that mitochondrial dysfunction can be overcome to treat age related decline Cytegenandapos s hypothesis is that exercise induces the secretion of blood borne proteins that act ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. Highly sensitive isothermal method and instrument for field diagnostics to facilitate malaria eradication

    SBC: CASCADE BIOSYSTEMS, INC.            Topic: NIAID

    Plasmodium falciparum is the most virulent form of malaria causing million deaths per year Success with patient treatment and a malaria eradication campaign depends significantly on our ability to detect new infections as early as possible in the field rural areas including asymptomatic cases preferably using a small amount of blood e g from a finger prick and to clearly discrim ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. A cloud based software platform to enhance reproducibility collaboration and translation of stem cell research

    SBC: Cellara, LLC            Topic: 400

    Project Summary Stem cell research has shown great potential to help treat or even cure a wide array of health conditions including cardiovascular and neurological disease cancer and diabetes This field is now beginning to move rapidly from the re search stage to clinical translation and commercial applications However it has been widely recognized that stem cell scientists have difficulty ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Graphene based Nanosensor Device for Rapid Onsite Detection of Dissolved Lead in Tap Water

    SBC: NANOAFFIX SCIENCE LLC            Topic: NIEHS

    PROJECT SUMMARY There is an increasing public concern about monitoring water quality in the entire drinking water supply system especially at the point of use spurred by recent water catastrophes such as the one in Flint Michigan that has caused severe health issues for thousands of children due to the unsafe level of lead in contaminated drinking water Current quantitative detection methods ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Field, clinic and lab preparation of emerging pathogens and other biological specimens for microscopy

    SBC: Microscopy Innovations, LLC            Topic: DHP16C004

    Biological tissues collection is problematic and risky even under ideal conditions: when collection occurs in remote locations, or by minimally-trained personnel, as may occur in response to an emerging disease threat, risks are magnified. This proposal addresses this issue by developing a Field Fixation Unit (FFU) for specimen collection that utilizes single-use capsules pre-loaded with fixative. ...

    STTR Phase I 2017 Department of DefenseDefense Health Program

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